Epigallocatechin-3-gallate inhibits IL-6 synthesis and suppresses transsignaling by enhancing soluble gp130 production. (Q36936364)

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14 January 2020

title

Epigallocatechin-3-gallate inhibits IL-6 synthesis and suppresses transsignaling by enhancing soluble gp130 production (English)

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14 January 2020

2

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14 January 2020

author name string

Salahuddin Ahmed

1

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14 January 2020

Kevin Kwan

3

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14 January 2020

Jeffrey H Ruth

4

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14 January 2020

Phillip L Campbell

5

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14 January 2020

Bradley J Rabquer

6

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14 January 2020

Angela Pakozdi

7

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14 January 2020

Alisa E Koch

8

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14 January 2020

language of work or name

English

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publication date

16 September 2008

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Proceedings of the National Academy of Sciences of the United States of America

14 January 2020

published in

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14 January 2020

volume

105

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14 January 2020

issue

38

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14 January 2020

page(s)

14692-14697

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Transgenic blockade of interleukin 6 transsignaling abrogates inflammation

14 January 2020

cites work

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IL-6 transsignaling: the in vivo consequences

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Distinct contribution of IL-6, TNF-alpha, IL-1, and IL-10 to T cell-mediated spontaneous autoimmune arthritis in mice

29 September 2017

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Pharmacokinetics and safety of green tea polyphenols after multiple-dose administration of epigallocatechin gallate and polyphenon E in healthy individuals

29 September 2017

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Tocotrienols induce IKBKAP expression: a possible therapy for familial dysautonomia

29 September 2017

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The paradigm of IL-6: from basic science to medicine

29 September 2017

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Apoptosis as a therapeutic tool in rheumatoid arthritis

29 September 2017

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Soluble gp130 is the natural inhibitor of soluble interleukin-6 receptor transsignaling responses

29 September 2017

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Cloning of novel soluble gp130 and detection of its neutralizing autoantibodies in rheumatoid arthritis

29 September 2017

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Angiogenesis and arthritis

29 September 2017

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Prevention of collagen-induced arthritis in mice by a polyphenolic fraction from green tea.

29 September 2017

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Interleukin 6 is required for the development of collagen-induced arthritis

29 September 2017

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Cloning and expression of an alternatively spliced mRNA encoding a soluble form of the human interleukin-6 signal transducer gp130

29 September 2017

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29 September 2017

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Targeted disruption of gp130, a common signal transducer for the interleukin 6 family of cytokines, leads to myocardial and hematological disorders

29 September 2017

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Regulation of alternative splicing in vivo by overexpression of antagonistic splicing factors

29 September 2017

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Continuous activation of gp130, a signal-transducing receptor component for interleukin 6-related cytokines, causes myocardial hypertrophy in mice

29 September 2017

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Green tea polyphenol epigallocatechin-3-gallate inhibits the IL-1 beta-induced activity and expression of cyclooxygenase-2 and nitric oxide synthase-2 in human chondrocytes

29 September 2017

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Epigallocatechin-3-gallate inhibits interleukin-1beta-induced expression of nitric oxide synthase and production of nitric oxide in human chondrocytes: suppression of nuclear factor kappaB activation by degradation of the inhibitor of nuclear factor

27 June 2018

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27 June 2018

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Regulation of interleukin-1beta-induced chemokine production and matrix metalloproteinase 2 activation by epigallocatechin-3-gallate in rheumatoid arthritis synovial fibroblasts.

4 September 2018

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Therapeutic potential of (-)-epigallocatechin 3-O-gallate on renal damage in diabetic nephropathy model rats.

4 September 2018

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Treatment of rheumatoid arthritis with humanized anti-interleukin-6 receptor antibody: a multicenter, double-blind, placebo-controlled trial

4 September 2018

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Green tea polyphenol epigallocatechin-3-gallate (EGCG) differentially inhibits interleukin-1 beta-induced expression of matrix metalloproteinase-1 and -13 in human chondrocytes

4 September 2018

1 reference

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Differential effects of FK506 and methotrexate on inflammatory cytokine levels in rat adjuvant-induced arthritis

4 September 2018

1 reference

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IL-4 adenoviral gene therapy reduces inflammation, proinflammatory cytokines, vascularization, and bony destruction in rat adjuvant-induced arthritis

4 September 2018

1 reference

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4 September 2018

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12 December 2020

Interleukin-6 (IL-6) induces the proliferation of synovial fibroblastic cells in the presence of soluble IL-6 receptor

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12 December 2020

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12 December 2020

The synovial expression and serum levels of interleukin-6, interleukin-11, leukemia inhibitory factor, and oncostatin M in rheumatoid arthritis

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12 December 2020

Blockage of interleukin-6 receptor ameliorates joint disease in murine collagen-induced arthritis

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12 December 2020

Delayed onset and reduced severity of collagen-induced arthritis in interleukin-6-deficient mice

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Interleukin-6 promotes cervical tumor growth by VEGF-dependent angiogenesis via a STAT3 pathway

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Soluble IL-6 Receptor Governs IL-6 Activity in Experimental Arthritis: Blockade of Arthritis Severity by Soluble Glycoprotein 130

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Interleukin-6 in synovial fluid and serum of patients with rheumatoid arthritis and other inflammatory arthritides

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Identifiers

DOI

10.1073/PNAS.0802675105

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18796608%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

0 references

1 reference

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14 January 2020

PubMed publication ID

18796608

1 reference