Intracellular signaling pathways pave roads to recovery for mood disorders (Q36939418)

17 August 2017

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title

Intracellular signaling pathways pave roads to recovery for mood disorders (English)

1 reference

17 August 2017

Keith Q Tanis

1

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17 August 2017

Ronald S Duman

series ordinal

2

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17 August 2017

language of work or name

English

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publication date

1 January 2007

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17 August 2017

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17 August 2017

volume

39

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17 August 2017

issue

7

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17 August 2017

page(s)

531-544

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The epidemiology of major depressive disorder: results from the National Comorbidity Survey Replication (NCS-R)

17 August 2017

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Why do we need new and better antidepressants?

21 January 2018

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21 January 2018

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21 January 2018

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Antidepressant-elicited changes in gene expression: remodeling of neuronal circuits as a new hypothesis for drug efficacy

21 January 2018

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The cellular neurobiology of depression

21 January 2018

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Depression: a case of neuronal life and death?

21 January 2018

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Untreated Depression and Hippocampal Volume Loss

21 January 2018

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Long-term treatment with paroxetine increases verbal declarative memory and hippocampal volume in posttraumatic stress disorder

21 January 2018

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Neuroimaging studies of mood disorders

21 January 2018

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Stress-induced changes in cerebral metabolites, hippocampal volume, and cell proliferation are prevented by antidepressant treatment with tianeptine

21 January 2018

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Antidepressants alter cell proliferation in the adult brain in vivo and in neural cultures in vitro.

21 January 2018

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Requirement of hippocampal neurogenesis for the behavioral effects of antidepressants

21 January 2018

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Abnormalities of cAMP signaling in affective disorders: implication for pathophysiology and treatment

21 January 2018

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Novel therapeutic approaches beyond the serotonin receptor.

21 January 2018

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Transmembrane signaling in the brain by serotonin, a key regulator of physiology and emotion

21 January 2018

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Emerging concepts and therapeutic implications of beta-adrenergic receptor subtype signaling

21 January 2018

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Molecular pharmacology of alpha 2-adrenoceptor subtypes

21 January 2018

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Molecular details of cAMP generation in mammalian cells: a tale of two systems

21 January 2018

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PKA isoforms, neural pathways, and behaviour: making the connection

21 January 2018

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https://api.crossref.org/works/10.1080%2F07853890701483270

Regulation of hippocampal synaptic plasticity by cyclic AMP-dependent protein kinases

21 January 2018

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https://api.crossref.org/works/10.1080%2F07853890701483270

Function and regulation of CREB family transcription factors in the nervous system

21 January 2018

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Update on the therapeutic potential of PDE4 inhibitors

21 January 2018

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https://api.crossref.org/works/10.1080%2F07853890701483270

Keynote review: phosphodiesterase-4 as a therapeutic target

21 January 2018

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https://api.crossref.org/works/10.1080%2F07853890701483270

Increased temporal cortex CREB concentrations and antidepressant treatment in major depression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890701483270

G Protein-coupled cyclic AMP signaling in postmortem brain of subjects with mood disorders: effects of diagnosis, suicide, and treatment at the time of death

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890701483270

Adenylyl cyclase activity and G-protein subunit levels in postmortem frontal cortex of suicide victims

21 January 2018

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https://api.crossref.org/works/10.1080%2F07853890701483270

Emerging experimental therapeutics for bipolar disorder: insights from the molecular and cellular actions of current mood stabilizers

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890701483270

Effects of valproic acid on beta-adrenergic receptors, G-proteins, and adenylyl cyclase in rat C6 glioma cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890701483270

Expression of the neurotrophin receptor trkB is regulated by the cAMP/CREB pathway in neurons.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890701483270

Transcriptional regulation of neuronal genes and its effect on neural functions: cumulative mRNA expression of PACAP and BDNF genes controlled by calcium and cAMP signals in neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890701483270

CAAT/enhancer-binding protein delta and cAMP-response element-binding protein mediate inducible expression of the nerve growth factor gene in the central nervous system.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890701483270

Human activin betaA gene. Identification of novel 5' exon, functional promoter, and enhancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890701483270

Insulin-like growth factor-I induces bcl-2 promoter through the transcription factor cAMP-response element-binding protein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890701483270

Electroconvulsive shock increases the phosphorylation of cyclic AMP response element binding protein at Ser-133 in rat hippocampus but not in cerebellum.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890701483270

Expression of the cAMP response element binding protein (CREB) in hippocampus produces an antidepressant effect.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890701483270

Selective phosphorylation of nuclear CREB by fluoxetine is linked to activation of CaM kinase IV and MAP kinase cascades

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890701483270

A role for AMPA receptors in mood disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890701483270

DARPP-32 mediates serotonergic neurotransmission in the forebrain

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890701483270

Involvement of striatal and extrastriatal DARPP-32 in biochemical and behavioral effects of fluoxetine (Prozac).

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890701483270

Role of neurotrophic factors in the etiology and treatment of mood disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890701483270

Reduced activation and expression of ERK1/2 MAP kinase in the post-mortem brain of depressed suicide subjects

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890701483270

Neurotrophin levels in postmortem brains of suicide victims and the effects of antemortem diagnosis and psychotropic drugs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890701483270

MAP kinase activation by fluoxetine and its relation to gene expression in cultured rat astrocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890701483270

Electroconvulsive seizures increase the expression of MAP kinase phosphatases in limbic regions of rat brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890701483270

Mood stabilizer valproate promotes ERK pathway-dependent cortical neuronal growth and neurogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890701483270

A role for MAP kinase signaling in behavioral models of depression and antidepressant treatment.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890701483270

Altered gene expression of brain-derived neurotrophic factor and receptor tyrosine kinase B in postmortem brain of suicide subjects

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890701483270

Decreased serum brain-derived neurotrophic factor levels in major depressed patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890701483270

Alterations of serum levels of brain-derived neurotrophic factor (BDNF) in depressed patients with or without antidepressants

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890701483270

Dysregulation of the fibroblast growth factor system in major depression

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890701483270

Immobilization stress reduced the expression of neurotrophins and their receptors in the rat brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890701483270

Chronic stress in the adult dentate gyrus reduces cell proliferation near the vasculature and VEGF and Flk-1 protein expression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890701483270

Electroconvulsive seizures regulate gene expression of distinct neurotrophic signaling pathways.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890701483270

VEGF is an essential mediator of the neurogenic and behavioral actions of antidepressants

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890701483270

Regulation of activin mRNA and Smad2 phosphorylation by antidepressant treatment in the rat brain: effects in behavioral models.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890701483270

Proteomic analysis of protein changes developing in rat hippocampus after chronic antidepressant treatment: Implications for depressive disorders and future therapies

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890701483270

Antidepressant treatments induce the expression of basic fibroblast growth factor in cortical and hippocampal neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890701483270

Effect of treatment on serum brain-derived neurotrophic factor levels in depressed patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890701483270

The effect of chronic antidepressant treatment on serum brain-derived neurotrophic factor levels in depressed patients: a preliminary study

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890701483270

Chronic lithium treatment increases the expression of brain-derived neurotrophic factor in the rat brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890701483270

A neurotrophic model for stress-related mood disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890701483270

Essential role of BDNF in the mesolimbic dopamine pathway in social defeat stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890701483270

Brain-derived neurotrophic factor in the ventral midbrain-nucleus accumbens pathway: a role in depression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890701483270

Central administration of IGF-I and BDNF leads to long-lasting antidepressant-like effects

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890701483270

Structure and regulation of MAPK phosphatases

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890701483270

21 January 2018

MAP kinase phosphatases

1 reference

https://api.crossref.org/works/10.1080%2F07853890701483270

Protein phosphatases and the regulation of mitogen-activated protein kinase signalling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890701483270

Attenuation of a phosphorylation-dependent activator by an HDAC-PP1 complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890701483270

Trk receptors: roles in neuronal signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890701483270

Regulation of phosphoinositide-specific phospholipase C

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890701483270

Protein kinase C isoforms as therapeutic targets in nervous system disease states

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890701483270

Protein kinase C and the cytoskeleton

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890701483270

Reduced Brain Inositol in Lithium-treated Rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890701483270

Increased brain myo-inositol 1-phosphate in lithium-treated rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890701483270

Chronic lithium and sodium valproate both decrease the concentration of myo-inositol and increase the concentration of inositol monophosphates in rat brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890701483270

Chronic treatment with lithium and pretreatment with excess inositol reduce inositol pool size in astrocytes by different mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890701483270

A common mechanism of action for three mood-stabilizing drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890701483270

The effect of lithium on expression of genes for inositol biosynthetic enzymes in mouse hippocampus; a comparison with the yeast model

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890701483270

Lithium and bipolar mood disorder: the inositol-depletion hypothesis revisited

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890701483270

Lithium treatment inhibits protein kinase C translocation in rat brain cortex

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890701483270

Increased association of brain protein kinase C with the receptor for activated C kinase-1 (RACK1) in bipolar affective disorder

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890701483270

Chronic lithium administration alters a prominent PKC substrate in rat hippocampus

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890701483270

Modulation of protein kinase C isozymes and substrates by lithium: the role of myo-inositol

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890701483270

Ziskind-Somerfeld Research Award. Protein kinase C signaling in the brain: molecular transduction of mood stabilization in the treatment of manic-depressive illness

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890701483270

Direct, activating interaction between glycogen synthase kinase-3beta and p53 after DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890701483270

Glycogen synthase kinase-3beta phosphorylates Bax and promotes its mitochondrial localization during neuronal apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890701483270

The multifaceted roles of glycogen synthase kinase 3beta in cellular signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890701483270

CREB DNA binding activity is inhibited by glycogen synthase kinase-3 beta and facilitated by lithium

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890701483270

Cellular function of phosphoinositide 3-kinases: implications for development, homeostasis, and cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890701483270

Multiplicity of mechanisms of serotonin receptor signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890701483270

Role of protein phosphatase-2A and -1 in the regulation of GSK-3, cdk5 and cdc2 and the phosphorylation of tau in rat forebrain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890701483270

A molecular mechanism for the effect of lithium on development

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890701483270

Lithium inhibits glycogen synthase kinase-3 activity and mimics wingless signalling in intact cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890701483270

Regulation of Akt and glycogen synthase kinase-3 beta phosphorylation by sodium valproate and lithium

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890701483270

Lithium-mediated phosphorylation of glycogen synthase kinase-3beta involves PI3 kinase-dependent activation of protein kinase C-alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890701483270

Lithium activates the serine/threonine kinase Akt-1 and suppresses glutamate-induced inhibition of Akt-1 activity in neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890701483270

In vivo evidence in the brain for lithium inhibition of glycogen synthase kinase-3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890701483270

The mood-stabilizing agent valproate inhibits the activity of glycogen synthase kinase-3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890701483270

Valproate regulates GSK-3-mediated axonal remodeling and synapsin I clustering in developing neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890701483270

Hypoxia activates glycogen synthase kinase-3 in mouse brain in vivo: protection by mood stabilizers and imipramine

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890701483270

In vivo regulation of glycogen synthase kinase-3beta (GSK3beta) by serotonergic activity in mouse brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890701483270

Chronic electroconvulsive seizure up-regulates beta-catenin expression in rat hippocampus: role in adult neurogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890701483270

Activation of protein kinase B (Akt) signaling after electroconvulsive shock in the rat hippocampus

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890701483270

Biphasic changes in the Ser-9 phosphorylation of glycogen synthase kinase-3beta after electroconvulsive shock in the rat brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890701483270

Antipsychotics alter the protein expression levels of beta-catenin and GSK-3 in the rat medial prefrontal cortex and striatum

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890701483270

Convergent evidence for impaired AKT1-GSK3beta signaling in schizophrenia

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890701483270

Rapid antidepressive-like activity of specific glycogen synthase kinase-3 inhibitor and its effect on beta-catenin in mouse hippocampus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890701483270

AR-A014418, a selective GSK-3 inhibitor, produces antidepressant-like effects in the forced swim test

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890701483270

Glycogen synthase kinase-3beta haploinsufficiency mimics the behavioral and molecular effects of lithium

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890701483270

Lithium antagonizes dopamine-dependent behaviors mediated by an AKT/glycogen synthase kinase 3 signaling cascade

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890701483270

Phosphodiesterase: overview of protein structures, potential therapeutic applications and recent progress in drug development

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890701483270

Sustained hippocampal chromatin regulation in a mouse model of depression and antidepressant action

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890701483270

Histone deacetylase is a direct target of valproic acid, a potent anticonvulsant, mood stabilizer, and teratogen

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890701483270

Glycogen synthase kinase 3: a drug target for CNS therapies

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890701483270

Targeting neurotrophic/growth factor expression and signaling for antidepressant drug development

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890701483270

10.1080/07853890701483270

21 January 2018

Identifiers

DOI

1 reference

17 August 2017

1 reference