Molecular genetics of papillary thyroid carcinoma: great expectations (Q36949765)

17 August 2017

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title

Molecular genetics of papillary thyroid carcinoma: great expectations (English)

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17 August 2017

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papillary thyroid cancer

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Vítor Trovisco

1

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17 August 2017

Paula Soares

2

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17 August 2017

Ana Preto

3

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17 August 2017

Patrícia Castro

4

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17 August 2017

Valdemar Máximo

5

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17 August 2017

Manuel Sobrinho-Simões

6

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17 August 2017

1 July 2007

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Arquivos Brasileiros de Endocrinologia e Metabologia

17 August 2017

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17 August 2017

51

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17 August 2017

5

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17 August 2017

643-653

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Origin and progression of thyroid epithelial tumours: cellular and molecular mechanisms

17 August 2017

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302007000500002

Diagnostic criteria in well-differentiated thyroid carcinomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302007000500002

PAX8-PPARgamma rearrangement is frequently detected in the follicular variant of papillary thyroid carcinoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302007000500002

Molecular pathology of well-differentiated thyroid carcinomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302007000500002

Sporadic ret-rearranged papillary carcinoma of the thyroid: a subset of slow growing, less aggressive thyroid neoplasms?

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302007000500002

Molecular pathobiology of thyroid neoplasms

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302007000500002

Neurotrophins and their receptors: signaling trios in complex biological systems.

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302007000500002

RET/PTC rearrangement in thyroid tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302007000500002

Defects in the kidney and enteric nervous system of mice lacking the tyrosine kinase receptor Ret

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302007000500002

Pathogenetic mechanisms in thyroid follicular-cell neoplasia

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302007000500002

ret rearrangements in Japanese pediatric and adult papillary thyroid cancers.

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302007000500002

Cancer after nuclear fallout: lessons from the Chernobyl accident

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302007000500002

RET/papillary thyroid cancer rearrangement in nonneoplastic thyrocytes: follicular cells of Hashimoto's thyroiditis share low-level recombination events with a subset of papillary carcinoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302007000500002

Neurotrophin signalling pathways regulating neuronal apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302007000500002

No correlation between BRAFV600E mutation and clinicopathological features of papillary thyroid carcinomas in Taiwan.

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302007000500002

The TRK-T1 fusion protein induces neoplastic transformation of thyroid epithelium.

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302007000500002

Molecular recognitions in the MAP kinase cascades

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302007000500002

The Raf/MEK/ERK pathway: new concepts of activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302007000500002

Structure and biological activity of v-raf, a unique oncogene transduced by a retrovirus

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302007000500002

Mutations of the BRAF gene in human cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302007000500002

RAF/RAS oncogenes and mismatch-repair status

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302007000500002

Mutations of the BRAF gene in papillary thyroid carcinoma in a Korean population

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302007000500002

BRAF(V599E) mutation is the leading genetic event in adult sporadic papillary thyroid carcinomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302007000500002

Mutations of the BRAF gene in papillary thyroid carcinoma and in Hashimoto's thyroiditis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302007000500002

Low prevalence of BRAF mutations in radiation-induced thyroid tumors in contrast to sporadic papillary carcinomas.

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302007000500002

Low frequency of BRAFT1796A mutations in childhood thyroid carcinomas.

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302007000500002

Frequency of BRAF T1796A mutation in papillary thyroid carcinoma relates to age of patient at diagnosis and not to radiation exposure.

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302007000500002

ret/PTC-1, -2, and -3 oncogene rearrangements in human thyroid carcinomas: implications for metastatic potential?

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302007000500002

Chernobyl and the future: too soon for a final diagnosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302007000500002

RAS point mutations and PAX8-PPAR gamma rearrangement in thyroid tumors: evidence for distinct molecular pathways in thyroid follicular carcinoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302007000500002

Molecular profile and clinical-pathologic features of the follicular variant of papillary thyroid carcinoma. An unusually high prevalence of ras mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302007000500002

Molecular genetic study comparing follicular variant versus classic papillary thyroid carcinomas: association of N-ras mutation in codon 61 with follicular variant.

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302007000500002

PAX8-PPARgamma1 fusion oncogene in human thyroid carcinoma [corrected]

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302007000500002

PAX8-peroxisome proliferator-activated receptor gamma (PPARgamma) disrupts normal PAX8 or PPARgamma transcriptional function and stimulates follicular thyroid cell growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302007000500002

Detection of the PAX8-PPAR gamma fusion oncogene in both follicular thyroid carcinomas and adenomas.

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302007000500002

Diseases of the mitochondrial DNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302007000500002

Somatic mutations of the mitochondrial genome in human colorectal tumours

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302007000500002

Somatic mitochondrial DNA (mtDNA) mutations in papillary thyroid carcinomas and differential mtDNA sequence variants in cases with thyroid tumours.

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302007000500002

Mitochondrial DNA somatic mutations (point mutations and large deletions) and mitochondrial DNA variants in human thyroid pathology: a study with emphasis on Hürthle cell tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302007000500002

Somatic and germline mutation in GRIM-19, a dual function gene involved in mitochondrial metabolism and cell death, is linked to mitochondrion-rich (Hurthle cell) tumours of the thyroid.

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302007000500002

Identification of GRIM-19, a novel cell death-regulatory gene induced by the interferon-beta and retinoic acid combination, using a genetic approach

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302007000500002

PTC is a novel rearranged form of the ret proto-oncogene and is frequently detected in vivo in human thyroid papillary carcinomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302007000500002

Potent mitogenicity of the RET/PTC3 oncogene correlates with its prevalence in tall-cell variant of papillary thyroid carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302007000500002

BRAF mutations in thyroid tumors are restricted to papillary carcinomas and anaplastic or poorly differentiated carcinomas arising from papillary carcinomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302007000500002

BRAF mutations in an Italian cohort of thyroid cancers.

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302007000500002

Familial adenomatous polyposis associated thyroid carcinoma: a distinct type of follicular cell neoplasm

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302007000500002

Somatic but not germline mutation of the APC gene in a case of cribriform-morular variant of papillary thyroid carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302007000500002

Somatic mutation of the APC gene in thyroid carcinoma associated with familial adenomatous polyposis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302007000500002

Detection of BRAF mutation on fine needle aspiration biopsy specimens: a new diagnostic tool for papillary thyroid cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302007000500002

A rapid and simple detection method for the BRAF(T1796A) mutation in fine-needle aspirated thyroid carcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302007000500002

Searching for RET/PTC rearrangements and BRAF V599E mutation in thyroid aspirates might contribute to establish a preoperative diagnosis of papillary thyroid carcinoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302007000500002

Mutational analysis of BRAF in fine needle aspiration biopsies of the thyroid: a potential application for the preoperative assessment of thyroid nodules

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302007000500002

Presence of the BRAF V600E point mutation in morphologically benign appearing thyroid inclusions of cervical lymph nodes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302007000500002

21 January 2018

Cancer statistics, 2005

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302007000500002

Clinical review 170: A systematic review and metaanalysis of the effectiveness of radioactive iodine remnant ablation for well-differentiated thyroid cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302007000500002

Ret/PTC activation does not influence clinical and pathological features of adult papillary thyroid carcinomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302007000500002

BRAF mutation predicts a poorer clinical prognosis for papillary thyroid cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302007000500002

Clinical implication of hot spot BRAF mutation, V599E, in papillary thyroid cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302007000500002

Evidence that one subset of anaplastic thyroid carcinomas are derived from papillary carcinomas due to BRAF and p53 mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302007000500002

BRAF mutations typical of papillary thyroid carcinoma are more frequently detected in undifferentiated than in insular and insular-like poorly differentiated carcinomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302007000500002

Targeted expression of BRAFV600E in thyroid cells of transgenic mice results in papillary thyroid cancers that undergo dedifferentiation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302007000500002

Prevalence and prognostic significance of tall cell variant of papillary thyroid carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302007000500002

New therapeutic approaches for metastatic thyroid carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302007000500002

Discovery of a novel Raf kinase inhibitor

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302007000500002

Mechanism of activation of the RAF-ERK signaling pathway by oncogenic mutations of B-RAF

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302007000500002

BRAF is a therapeutic target in aggressive thyroid carcinoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302007000500002

Inhibitors of Raf kinase activity block growth of thyroid cancer cells with RET/PTC or BRAF mutations in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302007000500002

Activated B-RAF is an Hsp90 client protein that is targeted by the anticancer drug 17-allylamino-17-demethoxygeldanamycin

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302007000500002

V600E B-Raf requires the Hsp90 chaperone for stability and is degraded in response to Hsp90 inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302007000500002

BAY 43-9006 inhibition of oncogenic RET mutants

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302007000500002

A phase II trial of rosiglitazone in patients with thyroglobulin-positive and radioiodine-negative differentiated thyroid cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302007000500002

Troglitazone, the peroxisome proliferator-activated receptor-gamma agonist, induces antiproliferation and redifferentiation in human thyroid cancer cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302007000500002

Novel high-affinity PPARgamma agonist alone and in combination with paclitaxel inhibits human anaplastic thyroid carcinoma tumor growth via p21WAF1/CIP1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302007000500002

Targeting BRAF in thyroid cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302007000500002

Oncogene profile of papillary thyroid carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302007000500002

The BRAF mutation is useful for prediction of clinical recurrence in low-risk patients with conventional papillary thyroid carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302007000500002

The BRAFV600E mutation is not associated with poor prognostic factors in Korean patients with conventional papillary thyroid microcarcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302007000500002

Correlation Between Genetic Alterations and Microscopic Features, Clinical Manifestations, and Prognostic Characteristics of Thyroid Papillary Carcinomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302007000500002

Alternative mutations of BRAF, RET and NTRK1 are associated with similar but distinct gene expression patterns in papillary thyroid cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1590%2FS0004-27302007000500002

The RET/PTC-RAS-BRAF linear signaling cascade mediates the motile and mitogenic phenotype of thyroid cancer cells

21 January 2018

2 references

30 December 2023

https://opencitations.net/index/api/v1/citations/10.1172/JCI200522758

30 December 2023

https://opencitations.net/index/api/v1/citations/10.1172/JCI22758

Identifiers

DOI

10.1590/S0004-27302007000500002

1 reference

17 August 2017

1 reference