Physiological functions of Atg6/Beclin 1: a unique autophagy-related protein (Q36950921)

17 August 2017

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title

Physiological functions of Atg6/Beclin 1: a unique autophagy-related protein (English)

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17 August 2017

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2

Daniel J Klionsky

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author name string

Yang Cao

series ordinal

1

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17 August 2017

1 October 2007

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17 August 2017

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17 August 2017

17

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17 August 2017

10

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17 August 2017

839-849

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https://scigraph.springernature.com/pub.10.1038/cr.2007.78

17 August 2017

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21 January 2018

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An Arabidopsis homolog of yeast ATG6/VPS30 is essential for pollen germination

21 January 2018

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Beclin 1, an autophagy gene essential for early embryonic development, is a haploinsufficient tumor suppressor

21 January 2018

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Functional and physical interaction between Bcl-X(L) and a BH3-like domain in Beclin-1

21 January 2018

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Crystal structure of the Bcl-XL-Beclin 1 peptide complex: Beclin 1 is a novel BH3-only protein

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Molecular mechanisms and regulation of specific and nonspecific autophagy pathways in yeast

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Genetic and phenotypic overlap between autophagy and the cytoplasm to vacuole protein targeting pathway

21 January 2018

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Cytoplasm-to-vacuole targeting and autophagy employ the same machinery to deliver proteins to the yeast vacuole

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Svp1p defines a family of phosphatidylinositol 3,5-bisphosphate effectors

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Protein transport to the yeast vacuole

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Two distinct Vps34 phosphatidylinositol 3-kinase complexes function in autophagy and carboxypeptidase Y sorting in Saccharomyces cerevisiae

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Convergence of multiple autophagy and cytoplasm to vacuole targeting components to a perivacuolar membrane compartment prior to de novo vesicle formation

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The pre-autophagosomal structure organized by concerted functions of APG genes is essential for autophagosome formation

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Hierarchy of Atg proteins in pre-autophagosomal structure organization

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BCL-2 in the crosshairs: tipping the balance of life and death

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Cloning and genomic organization of beclin 1, a candidate tumor suppressor gene on chromosome 17q21

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Autophagic and tumour suppressor activity of a novel Beclin1-binding protein UVRAG

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The evolutionarily conserved domain of Beclin 1 is required for Vps34 binding, autophagy and tumor suppressor function

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Functional specificity of the mammalian Beclin-Vps34 PI 3-kinase complex in macroautophagy versus endocytosis and lysosomal enzyme trafficking

21 January 2018

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Beclin-phosphatidylinositol 3-kinase complex functions at the trans-Golgi network

21 January 2018

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Bcl-2 antiapoptotic proteins inhibit Beclin 1-dependent autophagy

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BH3-only proteins in tumorigenesis and malignant melanoma

21 January 2018

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21 January 2018

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21 January 2018

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Ceramide-mediated macroautophagy involves inhibition of protein kinase B and up-regulation of beclin 1

21 January 2018

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Closed head injury induces upregulation of Beclin 1 at the cortical site of injury.

21 January 2018

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Urocortin inhibits Beclin1-mediated autophagic cell death in cardiac myocytes exposed to ischaemia/reperfusion injury

21 January 2018

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Regulation of intracellular accumulation of mutant Huntingtin by Beclin 1

21 January 2018

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Beta-amyloid is a substrate of autophagy in sporadic inclusion body myositis.

21 January 2018

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Class III phosphoinositide 3-kinase--Beclin1 complex mediates the amino acid-dependent regulation of autophagy in C2C12 myotubes.

21 January 2018

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Distinct roles of autophagy in the heart during ischemia and reperfusion: roles of AMP-activated protein kinase and Beclin 1 in mediating autophagy.

21 January 2018

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A novel protein complex linking the delta 2 glutamate receptor and autophagy: implications for neurodegeneration in lurcher mice

21 January 2018

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Influence of autophagy genes on ion-channel-dependent neuronal degeneration in Caenorhabditis elegans

21 January 2018

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Suppression of basal autophagy in neural cells causes neurodegenerative disease in mice

21 January 2018

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Loss of autophagy in the central nervous system causes neurodegeneration in mice

21 January 2018

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Autophagy genes protect against disease caused by polyglutamine expansion proteins in Caenorhabditis elegans

21 January 2018

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Autophagy in Niemann-Pick C disease is dependent upon Beclin-1 and responsive to lipid trafficking defects

21 January 2018

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PKR-dependent autophagic degradation of herpes simplex virus type 1.

21 January 2018

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https://api.crossref.org/works/10.1038%2FCR.2007.78

Autophagy regulates programmed cell death during the plant innate immune response.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.78

Autophagy recognizes intracellular Salmonella enterica serovar Typhimurium in damaged vacuoles

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.78

The two faces of autophagy: Coxiella and Mycobacterium

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.78

Autophagy vs. Group A Streptococcus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.78

Endogenous MHC class II processing of a viral nuclear antigen after autophagy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.78

Immune surveillance of intracellular pathogens via autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.78

Autophagy genes are essential for dauer development and life-span extension in C. elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.78

Autophagy regulates ageing in C. elegans.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.78

Regulation of an ATG7-beclin 1 program of autophagic cell death by caspase-8

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.78

Role of Bcl-2 family proteins in a non-apoptotic programmed cell death dependent on autophagy genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.78

Inhibition of macroautophagy triggers apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.78

Partial Beclin 1 silencing aggravates doxorubicin- and Fas-induced apoptosis in HepG2 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.78

Autophagy gene-dependent clearance of apoptotic cells during embryonic development

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.78

The role of autophagy in mitochondria maintenance: characterization of mitochondrial functions in autophagy-deficient S. cerevisiae strains

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.78

7 January 2021

Arabidopsis AtBECLIN 1/AtAtg6/AtVps30 is essential for pollen germination and plant development.

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.78

7 January 2021

Promotion of tumorigenesis by heterozygous disruption of the beclin 1 autophagy gene

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.78

7 January 2021

Protection against fatal Sindbis virus encephalitis by beclin, a novel Bcl-2-interacting protein

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.78

7 January 2021

Beclin 1-mediated macroautophagy involves regulation of caspase-9 expression in cervical cancer HeLa cells.

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.78

7 January 2021

BH3-only proteins and BH3 mimetics induce autophagy by competitively disrupting the interaction between Beclin 1 and Bcl-2/Bcl-X(L)

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.78

7 January 2021

Ambra1 regulates autophagy and development of the nervous system

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https://api.crossref.org/works/10.1038%2FCR.2007.78

7 January 2021

Macroautophagy as a pathomechanism in sporadic inclusion body myositis

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.78

7 January 2021

HSV-1 ICP34.5 confers neurovirulence by targeting the Beclin 1 autophagy protein

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.78

7 January 2021

Autophagy: a cell repair mechanism that retards ageing and age-associated diseases and can be intensified pharmacologically

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.78

7 January 2021

The involvement of macroautophagy in aging and anti-aging interventions

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https://api.crossref.org/works/10.1038%2FCR.2007.78

7 January 2021

Inactivation of the autophagy gene bec-1 triggers apoptotic cell death in C. elegans

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.78

7 January 2021

Identifiers

DOI

10.1038/CR.2007.78

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17 August 2017

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PubMed ID

17893711