HER3 is required for HER2-induced preneoplastic changes to the breast epithelium and tumor formation. (Q36957145)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22461506%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

title

HER3 is required for HER2-induced preneoplastic changes to the breast epithelium and tumor formation (English)

1 reference

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27 January 2020

8

1 reference

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27 January 2020

author name string

David B Vaught

1

1 reference

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27 January 2020

Jamie C Stanford

2

1 reference

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27 January 2020

Christian Young

3

1 reference

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27 January 2020

Donna J Hicks

4

1 reference

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27 January 2020

Frank Wheeler

5

1 reference

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27 January 2020

Cammie Rinehart

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22461506%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

Violeta Sánchez

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22461506%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

William J Muller

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22461506%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

Carlos L Arteaga

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22461506%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

Rebecca S Cook

11

1 reference

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27 January 2020

language of work or name

English

0 references

publication date

29 March 2012

1 reference

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27 January 2020

1 reference

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27 January 2020

volume

72

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27 January 2020

issue

10

1 reference

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27 January 2020

page(s)

2672-2682

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Pertuzumab plus trastuzumab plus docetaxel for metastatic breast cancer

27 January 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3693553

Targeting the HER/EGFR/ErbB family to prevent breast cancer.

29 September 2017

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Phosphoproteomic mass spectrometry profiling links Src family kinases to escape from HER2 tyrosine kinase inhibition.

29 September 2017

1 reference

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ErbB3 ablation impairs PI3K/Akt-dependent mammary tumorigenesis

29 September 2017

1 reference

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Transcriptional and posttranslational up-regulation of HER3 (ErbB3) compensates for inhibition of the HER2 tyrosine kinase

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3693553

Feedback upregulation of HER3 (ErbB3) expression and activity attenuates antitumor effect of PI3K inhibitors

29 September 2017

1 reference

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Resistance to HER2-directed antibodies and tyrosine kinase inhibitors: mechanisms and clinical implications

29 September 2017

1 reference

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New strategies in HER2-overexpressing breast cancer: many combinations of targeted drugs available

29 September 2017

1 reference

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H1047R phosphatidylinositol 3-kinase mutant enhances HER2-mediated transformation by heregulin production and activation of HER3

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3693553

Update of the National Surgical Adjuvant Breast and Bowel Project Study of Tamoxifen and Raloxifene (STAR) P-2 Trial: Preventing breast cancer

29 September 2017

1 reference

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Targeting the PI3K signaling pathway in cancer

29 September 2017

1 reference

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Loss of Phosphatase and Tensin homologue deleted on chromosome 10 engages ErbB3 and insulin-like growth factor-I receptor signaling to promote antiestrogen resistance in breast cancer

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3693553

PTEN deficiency in a luminal ErbB-2 mouse model results in dramatic acceleration of mammary tumorigenesis and metastasis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3693553

Regulation of mammary gland branching morphogenesis by EphA2 receptor tyrosine kinase

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3693553

Effect of lapatinib on the development of estrogen receptor-negative mammary tumors in mice

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3693553

Overcoming resistance to tyrosine kinase inhibitors: lessons learned from cancer cells treated with EGFR antagonists

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3693553

A central role for HER3 in HER2-amplified breast cancer: implications for targeted therapy

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3693553

ERBB3/HER3 and ERBB2/HER2 duet in mammary development and breast cancer

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3693553

Signaling through ShcA is required for transforming growth factor beta- and Neu/ErbB-2-induced breast cancer cell motility and invasion

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3693553

Mammary epithelial-specific disruption of the focal adhesion kinase blocks mammary tumor progression

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3693553

The ErbB2/ErbB3 heterodimer functions as an oncogenic unit: ErbB2 requires ErbB3 to drive breast tumor cell proliferation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3693553

The ErbB receptors and their role in cancer progression.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3693553

Elevated expression of activated forms of Neu/ErbB-2 and ErbB-3 are involved in the induction of mammary tumors in transgenic mice: implications for human breast cancer

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3693553

Generalized lacZ expression with the ROSA26 Cre reporter strain

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3693553

ErbB3 (HER3) interaction with the p85 regulatory subunit of phosphoinositide 3-kinase.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3693553

Cre-mediated gene deletion in the mammary gland

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3693553

Novel activating mutations in the neu proto-oncogene involved in induction of mammary tumors

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3693553

The biology of erbB-2/neu/HER-2 and its role in cancer

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3693553

Cooperative signaling of ErbB3 and ErbB2 in neoplastic transformation and human mammary carcinomas

29 September 2017

1 reference

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Exemestane for breast-cancer prevention in postmenopausal women.

29 September 2017

1 reference

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Gene targeting of ErbB3 using a Cre-mediated unidirectional DNA inversion strategy.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3693553

HER2 status in pure ductal carcinoma in situ and in the intraductal and invasive components of invasive ductal carcinoma determined by fluorescence in situ hybridization and immunohistochemistry.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3693553

Targeted disruption of ErbB2/Neu in the mammary epithelium results in impaired ductal outgrowth

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3693553

Targeted disruption of beta1-integrin in a transgenic mouse model of human breast cancer reveals an essential role in mammary tumor induction.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3693553

HER2-targeted therapy reduces incidence and progression of midlife mammary tumors in female murine mammary tumor virus huHER2-transgenic mice

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3693553

Gene expression profiling of neu-induced mammary tumors from transgenic mice reveals genetic and morphological similarities to ErbB2-expressing human breast cancers

4 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22461506

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Immunohistochemical distribution of c-erbB-2 in in situ breast carcinoma--a detailed morphological analysis

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22461506

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Immunohistochemical demonstration of c-erbB-2 protein in mammary ductal carcinoma in situ

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22461506

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1158/0008-5472.CAN-11-3594

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22461506%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22461506%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

1 reference