Novel selective allosteric activator of the M1 muscarinic acetylcholine receptor regulates amyloid processing and produces antipsychotic-like activity in rats. (Q36959071)

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scientific article published on October 2008

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English	Novel selective allosteric activator of the M1 muscarinic acetylcholine receptor regulates amyloid processing and produces antipsychotic-like activity in rats.	scientific article published on October 2008

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15 January 2020

Novel selective allosteric activator of the M1 muscarinic acetylcholine receptor regulates amyloid processing and produces antipsychotic-like activity in rats (English)

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15 January 2020

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15 January 2020

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15 January 2020

Todd E. Peterson

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Craig W. Lindsley

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Craig W Lindsley

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P. Jeffrey Conn

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P Jeffrey Conn

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Ashley E Brady

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James J Lah

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Allan I Levey

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M Sib Ansari

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Carrie K Jones

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15 January 2020

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Albert A Davis

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15 January 2020

Mohammed Noor Tantawy

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15 January 2020

Alexander S Kane

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15 January 2020

Thomas M Bridges

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J Phillip Kennedy

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Stefania R Bradley

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15 January 2020

Ronald M Baldwin

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15 January 2020

Robert M Kessler

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Ariel Y Deutch

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15 January 2020

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1 October 2008

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15 January 2020

Journal of Neuroscience

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41

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15 January 2020

10422-10433

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15 January 2020

An allosteric potentiator of M4 mAChR modulates hippocampal synaptic transmission

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Structural requirements of transmembrane domain 3 for activation by the M1 muscarinic receptor agonists AC-42, AC-260584, clozapine, and N-desmethylclozapine: evidence for three distinct modes of receptor activation

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A close structural analog of 2-methyl-6-(phenylethynyl)-pyridine acts as a neutral allosteric site ligand on metabotropic glutamate receptor subtype 5 and blocks the effects of multiple allosteric modulators

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Receptor mechanisms in the treatment of schizophrenia.

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The role of M1 muscarinic receptor agonism of N-desmethylclozapine in the unique clinical effects of clozapine

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N-desmethylclozapine, an allosteric agonist at muscarinic 1 receptor, potentiates N-methyl- d -aspartate receptor activity

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Ionotropic glutamate receptors as therapeutic targets in schizophrenia

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Allosteric drugs acting at muscarinic acetylcholine receptors.

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Hyperactivity, elevated dopaminergic transmission, and response to amphetamine in M1 muscarinic acetylcholine receptor-deficient mice

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Therapeutic opportunities from muscarinic receptor research

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Muscarinic receptor subtypes involved in hippocampal circuits

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Identification of a family of muscarinic acetylcholine receptor genes

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Discovery of an ectopic activation site on the M(1) muscarinic receptor

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10.1523/JNEUROSCI.1850-08.2008

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15 January 2020

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15 January 2020

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15 January 2020

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