Impact of Surface Polyethylene Glycol (PEG) Density on Biodegradable Nanoparticle Transport in Mucus ex Vivo and Distribution in Vivo (Q36961634)

17 August 2017

Impact of Surface Polyethylene Glycol (PEG) Density on Biodegradable Nanoparticle Transport in Mucus ex Vivo and Distribution in Vivo (English)

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17 August 2017

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11

Justin Hanes

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17 August 2017

Qingguo Xu

1

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17 August 2017

Laura M Ensign

2

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17 August 2017

Nicholas J Boylan

3

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17 August 2017

Arne Schön

4

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17 August 2017

Xiaoqun Gong

5

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17 August 2017

Jeh-Chang Yang

6

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17 August 2017

Nicholas W Lamb

7

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17 August 2017

Shutian Cai

8

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17 August 2017

Tao Yu

9

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17 August 2017

Ernesto Freire

10

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17 August 2017

language of work or name

English

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publication date

24 August 2015

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17 August 2017

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17 August 2017

9

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17 August 2017

9

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17 August 2017

9217-9227

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describes a project that uses

17 August 2017

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4890729/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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29 September 2017

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IgG in cervicovaginal mucus traps HSV and prevents vaginal herpes infections

29 September 2017

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Vaginal delivery of paclitaxel via nanoparticles with non-mucoadhesive surfaces suppresses cervical tumor growth

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Scalable method to produce biodegradable nanoparticles that rapidly penetrate human mucus

29 September 2017

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PEGylated PRINT nanoparticles: the impact of PEG density on protein binding, macrophage association, biodistribution, and pharmacokinetics

29 September 2017

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29 September 2017

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The effect of nanoparticle polyethylene glycol surface density on ligand-directed tumor targeting studied in vivo by dual modality imaging.

29 September 2017

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Nanoparticle size and surface chemistry determine serum protein adsorption and macrophage uptake

29 September 2017

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Drug carrier nanoparticles that penetrate human chronic rhinosinusitis mucus

29 September 2017

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Biodegradable nanoparticles composed entirely of safe materials that rapidly penetrate human mucus

29 September 2017

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29 September 2017

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Physical-chemical aspects of protein corona: relevance to in vitro and in vivo biological impacts of nanoparticles

29 September 2017

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The EPR effect: Unique features of tumor blood vessels for drug delivery, factors involved, and limitations and augmentation of the effect

29 September 2017

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Nanoparticles reveal that human cervicovaginal mucus is riddled with pores larger than viruses

29 September 2017

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Biodegradable polymer nanoparticles that rapidly penetrate the human mucus barrier.

29 September 2017

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Self-assembled lipid--polymer hybrid nanoparticles: a robust drug delivery platform.

29 September 2017

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The penetration of fresh undiluted sputum expectorated by cystic fibrosis patients by non-adhesive polymer nanoparticles.

29 September 2017

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Barrier properties of mucus

29 September 2017

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29 September 2017

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Controlled surface modification with poly(ethylene)glycol enhances diffusion of PLGA nanoparticles in human cervical mucus

29 September 2017

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Addressing the PEG mucoadhesivity paradox to engineer nanoparticles that "slip" through the human mucus barrier

29 September 2017

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Factors affecting the clearance and biodistribution of polymeric nanoparticles.

29 September 2017

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Rapid transport of large polymeric nanoparticles in fresh undiluted human mucus

29 September 2017

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Opsonization, biodistribution, and pharmacokinetics of polymeric nanoparticles

29 September 2017

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The rise and rise of drug delivery

29 September 2017

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Transport of PLA-PEG particles across the nasal mucosa: effect of particle size and PEG coating density.

29 September 2017

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Small-scale systems for in vivo drug delivery

29 September 2017

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Microbicide efficacy and toxicity tests in a mouse model for vaginal transmission of Chlamydia trachomatis.

29 September 2017

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Transmucosal delivery systems for calcitonin: a review

29 September 2017

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Biodegradable long-circulating polymeric nanospheres

29 September 2017

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The controlled intravenous delivery of drugs using PEG-coated sterically stabilized nanospheres.

29 September 2017

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Influence of poly(ethylene glycol) grafting density and polymer length on liposomes: relating plasma circulation lifetimes to protein binding.

27 June 2018

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Anti-PEG IgM Response against PEGylated Liposomes in Mice and Rats

27 June 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4890729

Distribution of a vaginal gel (Invisible Condom) before, during and after simulated sexual intercourse and its persistence when delivered by two different vaginal applicators: a magnetic resonance imaging study

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4890729

Vaginal distribution of Replens and K-Y Jelly using three imaging techniques

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4890729

Systematic investigation of the thermodynamics of HSA adsorption to N-iso-propylacrylamide/N-tert-butylacrylamide copolymer nanoparticles. Effects of particle size and hydrophobicity

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4890729

pH triggered release of protective poly(ethylene glycol)-b-polycation copolymers from liposomes

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4890729

Accelerated blood clearance of PEGylated liposomes following preceding liposome injection: effects of lipid dose and PEG surface-density and chain length of the first-dose liposomes.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4890729

Application of NMR spectroscopy to the characterization of PEG-stabilized lipid nanoparticles.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4890729

Biodistribution of long-circulating PEG-grafted nanocapsules in mice: effects of PEG chain length and density.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4890729

Injection of PEGylated liposomes in rats elicits PEG-specific IgM, which is responsible for rapid elimination of a second dose of PEGylated liposomes

4 September 2018

1 reference

12 December 2020

‘Stealth’ corona-core nanoparticles surface modified by polyethylene glycol (PEG): influences of the corona (PEG chain length and surface density) and of the core composition on phagocytic uptake and plasma protein adsorption

1 reference

12 December 2020

Biodistribution properties of nanoparticles based on mixtures of PLGA with PLGA-PEG diblock copolymers

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12 December 2020

Fluorescent Nanocrystals as Colloidal Probes in Complex Fluids Measured by Fluorescence Correlation Spectroscopy

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12 December 2020

Preparation of nanoparticles consisted of poly(L-lactide)-poly(ethylene glycol)-poly(L-lactide) and their evaluation in vitro

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12 December 2020

Vaginal distribution of two volumes of the novel microbicide gel cellulose sulfate (2.5 and 3.5 mL)

1 reference

12 December 2020

Identifiers

DOI

10.1021/ACSNANO.5B03876

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17 August 2017

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17 August 2017

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