Hedgehog signaling in development and homeostasis of the gastrointestinal tract (Q36967679)

17 August 2017

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title

Hedgehog signaling in development and homeostasis of the gastrointestinal tract (English)

1 reference

17 August 2017

Gijs R van den Brink

1

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17 August 2017

1 October 2007

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17 August 2017

Physiological Reviews

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17 August 2017

87

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17 August 2017

1343-1375

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17 August 2017

4

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GATA4, 5 and 6 mediate TGFbeta maintenance of endodermal gene expression in Xenopus embryos.

17 August 2017

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00054.2006

Arteries define the position of the thyroid gland during its developmental relocalisation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00054.2006

Sonic hedgehog directs specialised mesoderm differentiation in the intestine and pancreas

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00054.2006

Bmp signaling is required for intestinal growth and morphogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00054.2006

Expression of Cdx-2 in the mouse embryo and placenta: possible role in patterning of the extra-embryonic membranes

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00054.2006

Widespread requirement for Hedgehog ligand stimulation in growth of digestive tract tumours

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00054.2006

Gli2 is targeted for ubiquitination and degradation by beta-TrCP ubiquitin ligase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00054.2006

Linking colorectal cancer to Wnt signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00054.2006

Hedgehog morphogen in cardiovascular disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00054.2006

Repression of smoothened by patched-dependent (pro-)vitamin D3 secretion

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00054.2006

Hedgehog and Bmp genes are coexpressed at many diverse sites of cell-cell interaction in the mouse embryo

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00054.2006

A hedgehog-insensitive form of patched provides evidence for direct long-range morphogen activity of sonic hedgehog in the neural tube.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00054.2006

Paneth cell differentiation in the developing intestine of normal and transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00054.2006

Proteolytic processing yields two secreted forms of sonic hedgehog

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00054.2006

Mechanisms of left-right determination in vertebrates

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00054.2006

Regulation of early lung morphogenesis: questions, facts and controversies

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00054.2006

Mouse Dispatched homolog1 is required for long-range, but not juxtacrine, Hh signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00054.2006

Inhibition of Hedgehog signaling by direct binding of cyclopamine to Smoothened

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00054.2006

Small molecule modulation of Smoothened activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00054.2006

Palmitoylation is required for the production of a soluble multimeric Hedgehog protein complex and long-range signaling in vertebrates

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00054.2006

Vertebrate Hedgehog signalling modulated by induction of a Hedgehog-binding protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00054.2006

Morphogenesis in the fetal rat proximal colon: effects of cytochalasin D.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00054.2006

Cardiac and CNS defects in a mouse with targeted disruption of suppressor of fused

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00054.2006

Teratogen-mediated inhibition of target tissue response to Shh signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00054.2006

Vertebrate Smoothened functions at the primary cilium

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00054.2006

Thyroid Development and Its Disorders: Genetics and Molecular Mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00054.2006

Hedgehog induces opposite changes in turnover and subcellular localization of patched and smoothened

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00054.2006

Sonic hedgehog is required early in pancreatic islet development

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00054.2006

Transcription of sonic hedgehog, a potential factor for gastric morphogenesis and gastric mucosa maintenance, is up-regulated in acidic conditions

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00054.2006

Fetal endoderm primarily holds the temporal and positional information required for mammalian intestinal development

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00054.2006

Oxysterols are novel activators of the hedgehog signaling pathway in pluripotent mesenchymal cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00054.2006

Sonic hedgehog, a member of a family of putative signaling molecules, is implicated in the regulation of CNS polarity

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00054.2006

Hedgehog signaling in skeletal development

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00054.2006

Pax6 controls progenitor cell identity and neuronal fate in response to graded Shh signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00054.2006

Genetic deletion of sonic hedgehog causes hemiagenesis and ectopic development of the thyroid in mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00054.2006

Winged-helix, Hedgehog and Bmp genes are differentially expressed in distinct cell layers of the murine yolk sac

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00054.2006

Small-molecule modulators of Hedgehog signaling: identification and characterization of Smoothened agonists and antagonists

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00054.2006

Epithelial-mesenchymal interactions in differentiation of stomach epithelium in fetal mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00054.2006

Hedgehog signal activation in gastric pit cell and in diffuse-type gastric cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00054.2006

Familial Adenomatous Polyposis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00054.2006

Conservation of the hedgehog/patched signaling pathway from flies to mice: induction of a mouse patched gene by Hedgehog

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00054.2006

Differentiation and self-renewal in the mouse gastrointestinal epithelium

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00054.2006

Antero-posterior patterning of the vertebrate digestive tract: 40 years after Nicole Le Douarin's PhD thesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00054.2006

Mitochondrial DNA mutations are established in human colonic stem cells, and mutated clones expand by crypt fission.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00054.2006

Wnt signaling in the intestinal epithelium: from endoderm to cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00054.2006

Hepatic specification of the gut endoderm in vitro: cell signaling and transcriptional control.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00054.2006

Mutations of the human homolog of Drosophila patched in the nevoid basal cell carcinoma syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00054.2006

De novo crypt formation and juvenile polyposis on BMP inhibition in mouse intestine.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00054.2006

Gli2 and Gli3 localize to cilia and require the intraflagellar transport protein polaris for processing and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00054.2006

BMP signaling inhibits intestinal stem cell self-renewal through suppression of Wnt-beta-catenin signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00054.2006

Notochord repression of endodermal Sonic hedgehog permits pancreas development

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00054.2006

Genetics and biology of pancreatic ductal adenocarcinoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00054.2006

Nodal flow and the generation of left-right asymmetry.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00054.2006

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00054.2006

A cellular framework for gut-looping morphogenesis in zebrafish.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00054.2006

Germline mutations of the gene encoding bone morphogenetic protein receptor 1A in juvenile polyposis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00054.2006

Pathology of genetically engineered mouse models of pancreatic exocrine cancer: consensus report and recommendations.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00054.2006

Signaling from Smo to Ci/Gli: conservation and divergence of Hedgehog pathways from Drosophila to vertebrates

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00054.2006

Hedgehog signalling in the mouse requires intraflagellar transport proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00054.2006

A mouse model of greig cephalopolysyndactyly syndrome: the extra-toesJ mutation contains an intragenic deletion of the Gli3 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00054.2006

Expression of three mouse homologs of the Drosophila segment polarity gene cubitus interruptus, Gli, Gli-2, and Gli-3, in ectoderm- and mesoderm-derived tissues suggests multiple roles during postimplantation development

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00054.2006

Sonic hedgehog induces the segregation of patched and smoothened in endosomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00054.2006

Orchestrating ontogenesis: variations on a theme by sonic hedgehog

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00054.2006

Genetic mosaic analysis reveals that GATA-4 is required for proper differentiation of mouse gastric epithelium.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00054.2006

Human homolog of patched, a candidate gene for the basal cell nevus syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00054.2006

Conditional deletion of beta1 integrins in the intestinal epithelium causes a loss of Hedgehog expression, intestinal hyperplasia, and early postnatal lethality

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00054.2006

The making of the liver: developmental competence in foregut endoderm and induction of the hepatogenic program

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00054.2006

BOC, an Ig superfamily member, associates with CDO to positively regulate myogenic differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00054.2006

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00054.2006

GLI3 frameshift mutations cause autosomal dominant Pallister-Hall syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00054.2006

Identifying and counting epithelial cell types in the "corpus" of the mouse stomach

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00054.2006

Combined activities of hedgehog signaling inhibitors regulate pancreas development

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00054.2006

Hedgehog signaling regulates expansion of pancreatic epithelial cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00054.2006

Mouse dispatched mutants fail to distribute hedgehog proteins and are defective in hedgehog signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00054.2006

Hedgehog and PI-3 kinase signaling converge on Nmyc1 to promote cell cycle progression in cerebellar neuronal precursors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00054.2006

Gli3 null mice display glandular overgrowth of the developing stomach

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00054.2006

Intercellular signals regulating pancreas development and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00054.2006

Pancreas development is promoted by cyclopamine, a hedgehog signaling inhibitor

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00054.2006

Pax6 is essential for establishing ventral-dorsal cell boundaries in pituitary gland development

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00054.2006

No evidence for mutations or altered expression of the Suppressor of Fused gene (SUFU) in primitive neuroectodermal tumours

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00054.2006

Induction of pancreatic differentiation by signals from blood vessels.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00054.2006

Role of endothelial cells in early pancreas and liver development

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00054.2006

Autoproteolysis in hedgehog protein biogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00054.2006

Secretion and localized transcription suggest a role in positional signaling for products of the segmentation gene hedgehog

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00054.2006

Cholesterol modification of sonic hedgehog is required for long-range signaling activity and effective modulation of signaling by Ptc1

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00054.2006

Cholesterol modification restricts the spread of Shh gradient in the limb bud.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00054.2006

Specification of ventral neuron types is mediated by an antagonistic interaction between Shh and Gli3

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00054.2006

Sonic hedgehog is essential to foregut development

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00054.2006

Mouse intraflagellar transport proteins regulate both the activator and repressor functions of Gli transcription factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00054.2006

The Hedgehog response network: sensors, switches, and routers

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00054.2006

Frequent activation of the hedgehog pathway in advanced gastric adenocarcinomas.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00054.2006

Hedgehog-mediated patterning of the mammalian embryo requires transporter-like function of dispatched

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00054.2006

Epithelial hedgehog signals pattern the intestinal crypt-villus axis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00054.2006

Cis elements of the villin gene control expression in restricted domains of the vertical (crypt) and horizontal (duodenum, cecum) axes of the intestine.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00054.2006

Thymus organogenesis and molecular mechanisms of thymic epithelial cell differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00054.2006

Novel lipid modifications of secreted protein signals

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00054.2006

A novel somatic mouse model to survey tumorigenic potential applied to the Hedgehog pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00054.2006

Numb is a suppressor of Hedgehog signalling and targets Gli1 for Itch-dependent ubiquitination.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00054.2006

Cloning, expression, and chromosomal location of SHH and IHH: two human homologues of the Drosophila segment polarity gene hedgehog

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00054.2006

Anal atresia, vertebral, genital, and urinary tract anomalies: a primary polytopic developmental field defect identified through an epidemiological analysis of associations

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00054.2006

Loss of the retrograde motor for IFT disrupts localization of Smo to cilia and prevents the expression of both activator and repressor functions of Gli

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00054.2006

Two populations of node monocilia initiate left-right asymmetry in the mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00054.2006

Maturation of human fetal esophagus maintained in organ culture

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00054.2006

Purified Wnt5a protein activates or inhibits beta-catenin-TCF signaling depending on receptor context

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00054.2006

Anorectal malformations caused by defects in sonic hedgehog signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00054.2006

Essential function of Gli2 and Gli3 in the formation of lung, trachea and oesophagus

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00054.2006

Hh pathway expression in human gut tissues and in inflammatory gut diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00054.2006

Randomization of left-right asymmetry due to loss of nodal cilia generating leftward flow of extraembryonic fluid in mice lacking KIF3B motor protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00054.2006

Mutations affecting segment number and polarity in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00054.2006

Expression of Sonic hedgehog pathway genes is altered in colonic neoplasia

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00054.2006

Foxf1 and Foxf2 control murine gut development by limiting mesenchymal Wnt signaling and promoting extracellular matrix production

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00054.2006

Hedgehog signalling: how to get from Smo to Ci and Gli.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00054.2006

Sonic hedgehog signaling regulates Gli2 transcriptional activity by suppressing its processing and degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00054.2006

Lipoprotein particles are required for Hedgehog and Wingless signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00054.2006

Gene expression profile analysis of mouse colon embryonic development

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00054.2006

Hedgehog/Ras interactions regulate early stages of pancreatic cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00054.2006

Sonic hedgehog regulates branching morphogenesis in the mammalian lung

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00054.2006

A novel function for Hedgehog signalling in retinal pigment epithelium differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00054.2006

Hedgehog patterning activity: role of a lipophilic modification mediated by the carboxy-terminal autoprocessing domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00054.2006

The product of hedgehog autoproteolytic cleavage active in local and long-range signalling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00054.2006

Epithelial cells and their neighbors I. Role of intestinal myofibroblasts in development, repair, and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00054.2006

Hedgehog signalling in colorectal tumour cells: induction of apoptosis with cyclopamine treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00054.2006

The VATER association. Vertebral defects, Anal atresia, T-E fistula with esophageal atresia, Radial and Renal dysplasia: a spectrum of associated defects

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00054.2006

The phenotypic spectrum of GLI3 morphopathies includes autosomal dominant preaxial polydactyly type-IV and postaxial polydactyly type-A/B; No phenotype prediction from the position of GLI3 mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00054.2006

Development of esophageal epithelium in the fetal and neonatal mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00054.2006

Distinct mesodermal signals, including BMPs from the septum transversum mesenchyme, are required in combination for hepatogenesis from the endoderm

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00054.2006

Hedgehog signaling pathway is essential for pancreas specification in the zebrafish embryo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00054.2006

Genetic analysis reveals that PAX6 is required for normal transcription of pancreatic hormone genes and islet development

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00054.2006

Intraflagellar transport and cilium-based signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00054.2006

Evidence that loss of sonic hedgehog is an indicator of Helicobater pylori-induced atrophic gastritis progressing to gastric cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00054.2006

Mechanisms, mechanics and function of epithelial-mesenchymal transitions in early development

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00054.2006

Stomach development is dependent on fibroblast growth factor 10/fibroblast growth factor receptor 2b-mediated signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00054.2006

Regulation and function of the sonic hedgehog signal transduction pathway in isolated gastric parietal cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00054.2006

Genetic elimination of Suppressor of fused reveals an essential repressor function in the mammalian Hedgehog signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00054.2006

The Drosophila hedgehog gene is expressed specifically in posterior compartment cells and is a target of engrailed regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00054.2006

Patched acts catalytically to suppress the activity of Smoothened

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00054.2006

FGF-induced vesicular release of Sonic hedgehog and retinoic acid in leftward nodal flow is critical for left-right determination.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00054.2006

A dual role of FGF10 in proliferation and coordinated migration of epithelial leading edge cells during mouse eyelid development

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00054.2006

Mutations in SUFU predispose to medulloblastoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00054.2006

Multisite protein kinase A and glycogen synthase kinase 3beta phosphorylation leads to Gli3 ubiquitination by SCFbetaTrCP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00054.2006

The cell surface membrane proteins Cdo and Boc are components and targets of the Hedgehog signaling pathway and feedback network in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00054.2006

Hedgehog is an early and late mediator of pancreatic cancer tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00054.2006

Hedgehog signaling regulation of insulin production by pancreatic beta-cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00054.2006

Multiple left-right asymmetry defects in Shh(-/-) mutant mice unveil a convergence of the shh and retinoic acid pathways in the control of Lefty-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00054.2006

MYCN haploinsufficiency is associated with reduced brain size and intestinal atresias in Feingold syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00054.2006

The beta-catenin/TCF-4 complex imposes a crypt progenitor phenotype on colorectal cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00054.2006

Indian Hedgehog is an antagonist of Wnt signaling in colonic epithelial cell differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00054.2006

Sonic hedgehog expression correlates with fundic gland differentiation in the adult gastrointestinal tract

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00054.2006

Sonic hedgehog regulates gastric gland morphogenesis in man and mouse.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00054.2006

Divergence of hedgehog signal transduction mechanism between Drosophila and mammals

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00054.2006

Hedgehog-regulated processing of Gli3 produces an anterior/posterior repressor gradient in the developing vertebrate limb

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00054.2006

Disruption of hedgehog signaling reveals a novel role in intestinal morphogenesis and intestinal-specific lipid metabolism in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00054.2006

Vertebrate endoderm development

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00054.2006

Identification of a small molecule inhibitor of the hedgehog signaling pathway: effects on basal cell carcinoma-like lesions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00054.2006

Activating Smoothened mutations in sporadic basal-cell carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00054.2006

The ihog cell-surface proteins bind Hedgehog and mediate pathway activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00054.2006

Control of gut differentiation and intestinal-type gastric carcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00054.2006

A freely diffusible form of Sonic hedgehog mediates long-range signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00054.2006

Downregulation of Hedgehog signaling is required for organogenesis of the small intestine in Xenopus

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00054.2006

Cdo functions at multiple points in the Sonic Hedgehog pathway, and Cdo-deficient mice accurately model human holoprosencephaly

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00054.2006

Altered localization of Drosophila Smoothened protein activates Hedgehog signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00054.2006

Functional Smoothened is required for expression of GLI3 in colorectal carcinoma cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00054.2006

Pax6 is required for differentiation of glucagon-producing α-cells in mouse pancreas

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00054.2006

PPARβ/δ Regulates Paneth Cell Differentiation Via Controlling the Hedgehog Signaling Pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSREV.00054.2006

10.1152/PHYSREV.00054.2006

21 January 2018

Identifiers

DOI

1 reference

17 August 2017

1 reference

PubMed ID

17928586