Critical evaluation of 1H NMR metabonomics of serum as a methodology for disease risk assessment and diagnostics (Q37004712)

17 August 2017

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title

Critical evaluation of 1H NMR metabonomics of serum as a methodology for disease risk assessment and diagnostics (English)

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17 August 2017

1

Mika Ala-Korpela

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language of work or name

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1 January 2008

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Clinical Chemistry and Laboratory Medicine

17 August 2017

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17 August 2017

46

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17 August 2017

1

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17 August 2017

27-42

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Understanding 'Global' Systems Biology: Metabonomics and the Continuum of Metabolism

17 August 2017

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Metabonomics: NMR spectroscopy and pattern recognition analysis of body fluids and tissues for characterisation of xenobiotic toxicity and disease diagnosis

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Pharmaco-metabonomic phenotyping and personalized drug treatment

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A metabolomics perspective of human brain tumours

21 January 2018

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The Cinderella story of metabolic profiling: does metabolomics get to go to the functional genomics ball?

21 January 2018

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https://api.crossref.org/works/10.1515%2FCCLM.2008.006

Lipoprotein particle analysis by nuclear magnetic resonance spectroscopy.

21 January 2018

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https://api.crossref.org/works/10.1515%2FCCLM.2008.006

The inherent accuracy of 1H NMR spectroscopy to quantify plasma lipoproteins is subclass dependent.

21 January 2018

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Quantification of plasma lipids and apolipoproteins by use of proton NMR spectroscopy, multivariate and neural network analysis.

21 January 2018

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https://api.crossref.org/works/10.1515%2FCCLM.2008.006

Lipoprotein subclass profiles of hyperlipidemic diabetic mice measured by nuclear magnetic resonance spectroscopy

21 January 2018

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https://api.crossref.org/works/10.1515%2FCCLM.2008.006

Quantification of lipoprotein subclasses by proton nuclear magnetic resonance-based partial least-squares regression models.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FCCLM.2008.006

Nuclear magnetic resonance lipoprotein abnormalities in prediabetic subjects in the Insulin Resistance Atherosclerosis Study

21 January 2018

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https://api.crossref.org/works/10.1515%2FCCLM.2008.006

Low-density lipoprotein particle number and risk for cardiovascular disease

21 January 2018

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https://api.crossref.org/works/10.1515%2FCCLM.2008.006

Measurement issues related to lipoprotein heterogeneity

21 January 2018

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https://api.crossref.org/works/10.1515%2FCCLM.2008.006

LDL particle subclasses, LDL particle size, and carotid atherosclerosis in the Multi-Ethnic Study of Atherosclerosis (MESA).

21 January 2018

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https://api.crossref.org/works/10.1515%2FCCLM.2008.006

Increased small low-density lipoprotein particle number: a prominent feature of the metabolic syndrome in the Framingham Heart Study

21 January 2018

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https://api.crossref.org/works/10.1515%2FCCLM.2008.006

Value of low-density lipoprotein particle number and size as predictors of coronary artery disease in apparently healthy men and women: the EPIC-Norfolk Prospective Population Study

21 January 2018

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The effect of atorvastatin on serum lipids, lipoproteins and NMR spectroscopy defined lipoprotein subclasses in type 2 diabetic patients with ischaemic heart disease

21 January 2018

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https://api.crossref.org/works/10.1515%2FCCLM.2008.006

Nuclear magnetic resonance-determined lipoprotein subclass profile in the DCCT/EDIC cohort: associations with carotid intima-media thickness.

21 January 2018

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https://api.crossref.org/works/10.1515%2FCCLM.2008.006

Insulin resistance and adiposity influence lipoprotein size and subclass concentrations. Results from the Insulin Resistance Atherosclerosis Study

21 January 2018

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Comparison of ultracentrifugation and nuclear magnetic resonance spectroscopy in the quantification of triglyceride-rich lipoproteins after an oral fat load.

21 January 2018

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https://api.crossref.org/works/10.1515%2FCCLM.2008.006

Effect of orlistat on postprandial lipemia, NMR lipoprotein subclass profiles and particle size

21 January 2018

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https://api.crossref.org/works/10.1515%2FCCLM.2008.006

Disparate LDL Phenotypic Classification among 4 Different Methods Assessing LDL Particle Characteristics

21 January 2018

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Study of agreement between LDL size as measured by nuclear magnetic resonance and gradient gel electrophoresis.

21 January 2018

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https://api.crossref.org/works/10.1515%2FCCLM.2008.006

Lipoprotein subclasses and atherosclerosis

21 January 2018

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https://api.crossref.org/works/10.1515%2FCCLM.2008.006

Low-grade albuminuria and incidence of cardiovascular disease events in nonhypertensive and nondiabetic individuals: the Framingham Heart Study

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FCCLM.2008.006

1H NMR metabonomics of plasma lipoprotein subclasses: elucidation of metabolic clustering by self-organising maps.

21 January 2018

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https://api.crossref.org/works/10.1515%2FCCLM.2008.006

Characterization and molecular detection of atherothrombosis by magnetic resonance--potential tools for individual risk assessment and diagnostics

21 January 2018

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Chemometrics in metabonomics.

21 January 2018

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https://api.crossref.org/works/10.1515%2FCCLM.2008.006

A novel Bayesian approach to quantify clinical variables and to determine their spectroscopic counterparts in 1H NMR metabonomic data.

21 January 2018

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https://api.crossref.org/works/10.1515%2FCCLM.2008.006

Quantification of biomedical NMR data using artificial neural network analysis: lipoprotein lipid profiles from 1H NMR data of human plasma

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FCCLM.2008.006

Statistical total correlation spectroscopy: an exploratory approach for latent biomarker identification from metabolic 1H NMR data sets

21 January 2018

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Statistical heterospectroscopy, an approach to the integrated analysis of NMR and UPLC-MS data sets: application in metabonomic toxicology studies

21 January 2018

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NMR spectral quantitation by principal component analysis

21 January 2018

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Chemometric contributions to the evolution of metabonomics: mathematical solutions to characterising and interpreting complex biological NMR spectra

21 January 2018

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Independent component analysis for automated decomposition of in vivo magnetic resonance spectra.

21 January 2018

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Independent component analysis to proton spectroscopic imaging data of human brain tumours

21 January 2018

1 reference

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Evaluation of the orthogonal projection on latent structure model limitations caused by chemical shift variability and improved visualization of biomarker changes in 1H NMR spectroscopic metabonomic studies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FCCLM.2008.006

Sample classification based on Bayesian spectral decomposition of metabonomic NMR data sets

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FCCLM.2008.006

Visualizing metabolic changes in breast-cancer tissue using 1H-NMR spectroscopy and self-organizing maps

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FCCLM.2008.006

Application of self-organizing maps for the detection and classification of human blood plasma lipoprotein lipid profiles on the basis of 1H NMR spectroscopy data

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FCCLM.2008.006

Automated analysis of proton NMR spectra from combinatorial rapid parallel synthesis using self-organizing maps

21 January 2018

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https://api.crossref.org/works/10.1515%2FCCLM.2008.006

Metabonomics technologies and their applications in physiological monitoring, drug safety assessment and disease diagnosis

21 January 2018

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Neural networks evaluating NMR data: an approach to visualize similarities and relationships of sol-gel derived inorganic-organic and organometallic hybrid polymers

21 January 2018

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Serum 1H-nuclear magnetic spectroscopy followed by principal component analysis and hierarchical cluster analysis to demonstrate effects of statins on hyperlipidemic patients

21 January 2018

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Proton NMR analysis of plasma is a weak predictor of coronary artery disease.

21 January 2018

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Sex and age differences in lipoprotein subclasses measured by nuclear magnetic resonance spectroscopy: the Framingham Study.

21 January 2018

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Application of chemometrics to 1H NMR spectroscopic data to investigate a relationship between human serum metabolic profiles and hypertension

21 January 2018

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Evolving concepts in the triad of atherosclerosis, inflammation and thrombosis

21 January 2018

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Molecular, cellular and functional imaging of atherothrombosis

21 January 2018

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From vulnerable plaque to vulnerable patient: a call for new definitions and risk assessment strategies: Part I.

21 January 2018

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The role of analytical sciences in medical systems biology

21 January 2018

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Impact of analytical bias in metabonomic studies of human blood serum and plasma.

21 January 2018

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Proton nuclear magnetic resonance spectroscopy of body fluids in the field of inborn errors of metabolism.

21 January 2018

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Pattern recognition and biomarker validation using quantitative 1H-NMR-based metabolomics

21 January 2018

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Analytical strategies in metabonomics

21 January 2018

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Detection of malignant tumors. Water-suppressed proton nuclear magnetic resonance spectroscopy of plasma

21 January 2018

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An NMR blood test for cancer: a critical assessment

21 January 2018

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Detection of epithelial ovarian cancer using 1H-NMR-based metabonomics

21 January 2018

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Cancer biomarkers: knowing the present and predicting the future

21 January 2018

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The challenges of modeling mammalian biocomplexity

21 January 2018

1 reference

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Applying biofluid 1H NMR-based metabonomic techniques to distinguish between HIV-1 positive/AIDS patients on antiretroviral treatment and HIV-1 negative individuals

21 January 2018

1 reference

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Lipoprotein subclasses and particle sizes and their relationship with coronary artery calcification in men and women with and without type 1 diabetes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FCCLM.2008.006

Serum lipoproteins in the diabetes control and complications trial/epidemiology of diabetes intervention and complications cohort: associations with gender and glycemia

21 January 2018

1 reference

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Diabetic retinopathy and serum lipoprotein subclasses in the DCCT/EDIC cohort

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FCCLM.2008.006

Apolipoprotein C-III protein concentrations and gene polymorphisms in type 1 diabetes: associations with lipoprotein subclasses.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FCCLM.2008.006

Effects of insulin resistance and type 2 diabetes on lipoprotein subclass particle size and concentration determined by nuclear magnetic resonance

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FCCLM.2008.006

Use of relaxation-edited one-dimensional and two dimensional nuclear magnetic resonance spectroscopy to improve detection of small metabolites in blood plasma

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FCCLM.2008.006

Metabolic profiling of plasma from discordant schizophrenia twins: correlation between lipid signals and global functioning in female schizophrenia patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FCCLM.2008.006

The application of NMR-based metabonomics in neurological disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FCCLM.2008.006

Analytical reproducibility in (1)H NMR-based metabonomic urinalysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FCCLM.2008.006

A 1H NMR-based metabonomic study of urine and plasma samples obtained from healthy human subjects

21 January 2018

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https://api.crossref.org/works/10.1515%2FCCLM.2008.006

1H NMR studies of human blood plasma. Assignment of resonances for lipoproteins.

21 January 2018

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https://api.crossref.org/works/10.1515%2FCCLM.2008.006

Factors affecting 1H NMR spectra of blood plasma: cancer, diet and freezing.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FCCLM.2008.006

Optimisation of collection, storage and preparation of rat plasma for 1H NMR spectroscopic analysis in toxicology studies to determine inherent variation in biochemical profiles

21 January 2018

1 reference

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Global systems biology, personalized medicine and molecular epidemiology

21 January 2018

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Expanding the cardiovascular mandate: from treatment to the protection of health

21 January 2018

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Use of1H NMR-determined diffusion coefficients to characterize lipoprotein fractions in human blood plasma

21 January 2018

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Statistical Correlation and Projection Methods for Improved Information Recovery from Diffusion-Edited NMR Spectra of Biological Samples

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FCCLM.2008.006

Rapid and noninvasive diagnosis of the presence and severity of coronary heart disease using 1H-NMR-based metabonomics

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FCCLM.2008.006

Metabolic characterisation of plasma in juveniles with glycogen storage disease type 1a (GSD1a) by high-resolution1H NMR spectroscopy

21 January 2018

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Should advanced lipoprotein testing be used in clinical practice?

21 January 2018

1 reference

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Metabonomics, dietary influences and cultural differences: a 1H NMR-based study of urine samples obtained from healthy British and Swedish subjects

21 January 2018

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21 January 2018

Identifiers

DOI

10.1515/CCLM.2008.006

1 reference

17 August 2017

1 reference

PubMed ID

18020967