Nuclear receptors in macrophages: a link between metabolism and inflammation. (Q37005645)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18022390%20AND%20SRC:MED&resulttype=core&format=json

26 December 2019

review article

1 reference

title

Nuclear receptors in macrophages: a link between metabolism and inflammation (English)

1 reference

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26 December 2019

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2

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26 December 2019

author name string

Attila Szanto

series ordinal

1

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26 December 2019

language of work or name

English

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publication date

20 November 2007

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26 December 2019

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18022390%20AND%20SRC:MED&resulttype=core&format=json

26 December 2019

volume

582

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18022390%20AND%20SRC:MED&resulttype=core&format=json

26 December 2019

page(s)

106-116

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26 December 2019

issue

1

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26 December 2019

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Oxidized LDL regulates macrophage gene expression through ligand activation of PPARgamma

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Peroxisome proliferator-activated receptor gamma ligands inhibit development of atherosclerosis in LDL receptor-deficient mice

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Troglitazone inhibits atherosclerosis in apolipoprotein E-knockout mice: pleiotropic effects on CD36 expression and HDL.

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Conditional disruption of the peroxisome proliferator-activated receptor gamma gene in mice results in lowered expression of ABCA1, ABCG1, and apoE in macrophages and reduced cholesterol efflux.

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Conditional knockout of macrophage PPARgamma increases atherosclerosis in C57BL/6 and low-density lipoprotein receptor-deficient mice

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Crosstalk between LXR and Toll-like Receptor Signaling Mediates Bacterial and Viral Antagonism of Cholesterol Metabolism

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Autoregulation of the human liver X receptor alpha promoter

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21 January 2018

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Synthetic LXR ligand inhibits the development of atherosclerosis in mice

21 January 2018

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Control of cellular cholesterol efflux by the nuclear oxysterol receptor LXR alpha

21 January 2018

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The gene encoding ATP-binding cassette transporter 1 is mutated in Tangier disease

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Mutations in ABC1 in Tangier disease and familial high-density lipoprotein deficiency

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Tangier disease is caused by mutations in the gene encoding ATP-binding cassette transporter 1

21 January 2018

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Human white/murine ABC8 mRNA levels are highly induced in lipid-loaded macrophages. A transcriptional role for specific oxysterols

21 January 2018

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Regulation of ATP-binding cassette sterol transporters ABCG5 and ABCG8 by the liver X receptors alpha and beta.

21 January 2018

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LXR-dependent gene expression is important for macrophage survival and the innate immune response

21 January 2018

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Activation of liver X receptors and retinoid X receptors prevents bacterial-induced macrophage apoptosis

21 January 2018

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A role for the apoptosis inhibitory factor AIM/Spalpha/Api6 in atherosclerosis development

21 January 2018

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An oxysterol signalling pathway mediated by the nuclear receptor LXR alpha

21 January 2018

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Structural requirements of ligands for the oxysterol liver X receptors LXRalpha and LXRbeta

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Activation of the nuclear receptor LXR by oxysterols defines a new hormone response pathway

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Activities of recombinant human cytochrome P450c27 (CYP27) which produce intermediates of alternative bile acid biosynthetic pathways

21 January 2018

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Oxysterols present in atherosclerotic tissue decrease the expression of lipoprotein lipase messenger RNA in human monocyte-derived macrophages

21 January 2018

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Sterol 27-hydroxylase deficiency: a rare cause of xanthomas in normocholesterolemic humans.

21 January 2018

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Cerebrotendinous Xanthomatosis

21 January 2018

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Transcriptional regulation of human CYP27 integrates retinoid, peroxisome proliferator-activated receptor, and liver X receptor signaling in macrophages

21 January 2018

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Adipocyte enhancer-binding protein 1 is a potential novel atherogenic factor involved in macrophage cholesterol homeostasis and inflammation

21 January 2018

1 reference

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Markedly reduced bile acid synthesis but maintained levels of cholesterol and vitamin D metabolites in mice with disrupted sterol 27-hydroxylase gene.

21 January 2018

1 reference

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Disruption of the sterol 27-hydroxylase gene in mice results in hepatomegaly and hypertriglyceridemia. Reversal by cholic acid feeding.

21 January 2018

1 reference

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Identification of bile acid precursors as endogenous ligands for the nuclear xenobiotic pregnane X receptor

21 January 2018

1 reference

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Liver X receptor (LXR) regulation of the LXRalpha gene in human macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2007.11.020

The PPARdelta agonist GW0742X reduces atherosclerosis in LDLR(-/-) mice

21 January 2018

1 reference

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PPARdelta is a very low-density lipoprotein sensor in macrophages

21 January 2018

1 reference

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Transcriptional repression of atherogenic inflammation: modulation by PPARdelta

21 January 2018

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Peroxisome proliferator-activated receptor delta promotes very low-density lipoprotein-derived fatty acid catabolism in the macrophage

21 January 2018

1 reference

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Reduced cholesterol absorption upon PPARdelta activation coincides with decreased intestinal expression of NPC1L1.

21 January 2018

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The role of PPAR-gamma in macrophage differentiation and cholesterol uptake.

21 January 2018

1 reference

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Peroxisome proliferation-activated receptor (PPAR)gamma is not necessary for synthetic PPARgamma agonist inhibition of inducible nitric-oxide synthase and nitric oxide

21 January 2018

1 reference

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A SUMOylation-dependent pathway mediates transrepression of inflammatory response genes by PPAR-gamma

21 January 2018

1 reference

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Parallel SUMOylation-dependent pathways mediate gene- and signal-specific transrepression by LXRs and PPARgamma

21 January 2018

1 reference

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Decreased atherosclerosis in mice deficient in both macrophage colony-stimulating factor (op) and apolipoprotein E

21 January 2018

1 reference

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Granulocyte colony-stimulating factor and granulocyte macrophage colony-stimulating factor exacerbate atherosclerosis in apolipoprotein E-deficient mice.

21 January 2018

1 reference

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Endothelial expression of a mononuclear leukocyte adhesion molecule during atherogenesis

21 January 2018

1 reference

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Absence of P-selectin delays fatty streak formation in mice

21 January 2018

1 reference

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The combined role of P- and E-selectins in atherosclerosis

21 January 2018

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A major role for VCAM-1, but not ICAM-1, in early atherosclerosis

21 January 2018

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Decreased lesion formation in CCR2-/- mice reveals a role for chemokines in the initiation of atherosclerosis

21 January 2018

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A leukocyte homologue of the IL-8 receptor CXCR-2 mediates the accumulation of macrophages in atherosclerotic lesions of LDL receptor-deficient mice

21 January 2018

1 reference

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Decreased atherosclerotic lesion formation in CX3CR1/apolipoprotein E double knockout mice.

21 January 2018

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Macrophage migration inhibitory factor deficiency impairs atherosclerosis in low-density lipoprotein receptor-deficient mice

21 January 2018

1 reference

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MIF is a noncognate ligand of CXC chemokine receptors in inflammatory and atherogenic cell recruitment

21 January 2018

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Oxidized LDL reduces monocyte CCR2 expression through pathways involving peroxisome proliferator-activated receptor gamma

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2007.11.020

The mouse CCR2 gene is regulated by two promoters that are responsive to plasma cholesterol and peroxisome proliferator-activated receptor gamma ligands.

21 January 2018

1 reference

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Expression of peroxisome proliferator-activated receptor-gamma in macrophage suppresses experimentally induced colitis

21 January 2018

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Pattern recognition receptors: doubling up for the innate immune response

21 January 2018

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Molecular cloning of a novel scavenger receptor for oxidized low density lipoprotein, SR-PSOX, on macrophages

21 January 2018

1 reference

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Targeted disruption of the class B scavenger receptor CD36 protects against atherosclerotic lesion development in mice

21 January 2018

1 reference

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Stem cell transplantation reveals that absence of macrophage CD36 is protective against atherosclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2007.11.020

Macrophage scavenger receptor CD36 is the major receptor for LDL modified by monocyte-generated reactive nitrogen species

21 January 2018

1 reference

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Loss of receptor-mediated lipid uptake via scavenger receptor A or CD36 pathways does not ameliorate atherosclerosis in hyperlipidemic mice

21 January 2018

1 reference

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Loss of SR-BI expression leads to the early onset of occlusive atherosclerotic coronary artery disease, spontaneous myocardial infarctions, severe cardiac dysfunction, and premature death in apolipoprotein E-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2007.11.020

Inactivation of macrophage scavenger receptor class B type I promotes atherosclerotic lesion development in apolipoprotein E-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2007.11.020

Dual role for scavenger receptor class B, type I on bone marrow-derived cells in atherosclerotic lesion development

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2007.11.020

Lack of Toll-like receptor 4 or myeloid differentiation factor 88 reduces atherosclerosis and alters plaque phenotype in mice deficient in apolipoprotein E

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2007.11.020

Thematic review series: The immune system and atherogenesis. Paying the price for pathogen protection: toll receptors in atherogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2007.11.020

Modulation of atherosclerosis in mice by Toll-like receptor 2

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2007.11.020

Interleukin-4-dependent production of PPAR-gamma ligands in macrophages by 12/15-lipoxygenase

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2007.11.020

Dual promoter structure of mouse and human fatty acid translocase/CD36 genes and unique transcriptional activation by peroxisome proliferator-activated receptor alpha and gamma ligands

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2007.11.020

The peroxisome proliferator-activated receptor-gamma is a negative regulator of macrophage activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2007.11.020

PPARgamma regulates adipocyte cholesterol metabolism via oxidized LDL receptor 1

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2007.11.020

CXCL16 is a marker of inflammation, atherosclerosis, and acute coronary syndromes in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2007.11.020

IFN-gamma potentiates atherosclerosis in ApoE knock-out mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2007.11.020

Exogenous interferon-gamma enhances atherosclerosis in apolipoprotein E-/- mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2007.11.020

Influence of interferon-gamma on the extent and phenotype of diet-induced atherosclerosis in the LDLR-deficient mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2007.11.020

Reduced atherosclerosis in interleukin-18 deficient apolipoprotein E-knockout mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2007.11.020

Cross-regulatory roles of interleukin (IL)-12 and IL-10 in atherosclerosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2007.11.020

Selective interleukin-12 synthesis defect in 12/15-lipoxygenase-deficient macrophages associated with reduced atherosclerosis in a mouse model of familial hypercholesterolemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2007.11.020

The role of interleukin-4 and interleukin-12 in the progression of atherosclerosis in apolipoprotein E-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2007.11.020

Blockade of interleukin-12 function by protein vaccination attenuates atherosclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2007.11.020

Interleukin 12 induces T-cell recruitment into the atherosclerotic plaque

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2007.11.020

Interleukin-4 deficiency decreases atherosclerotic lesion formation in a site-specific manner in female LDL receptor-/- mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2007.11.020

Functional CD40 ligand is expressed on human vascular endothelial cells, smooth muscle cells, and macrophages: implications for CD40-CD40 ligand signaling in atherosclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2007.11.020

Reduction of atherosclerosis in mice by inhibition of CD40 signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2007.11.020

Requirement for CD154 in the progression of atherosclerosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2007.11.020

Regulation of the Hedgehog and Wingless signalling pathways by the F-box/WD40-repeat protein Slimb

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2007.11.020

15-deoxy-delta 12,14-prostaglandin J2 inhibits multiple steps in the NF-kappa B signaling pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2007.11.020

PPARgamma and PPARdelta negatively regulate specific subsets of lipopolysaccharide and IFN-gamma target genes in macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2007.11.020

Inhibition of IL-10-induced STAT3 activation by 15-deoxy-Delta12,14-prostaglandin J2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2007.11.020

Inhibition of transforming growth factor-beta signaling accelerates atherosclerosis and induces an unstable plaque phenotype in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2007.11.020

Peroxisome proliferator-activated receptor-gamma ligands inhibit TGF-beta 1-induced fibronectin expression in glomerular mesangial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2007.11.020

Pioglitazone attenuates TGF-beta(1)-induction of fibronectin synthesis and its splicing variant in human mesangial cells via activation of peroxisome proliferator-activated receptor (PPAR)gamma

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2007.11.020

PPARgamma agonists prevent TGFbeta1/Smad3-signaling in human hepatic stellate cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2007.11.020

Increased expression of matrix metalloproteinases and matrix degrading activity in vulnerable regions of human atherosclerotic plaques

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2007.11.020

Inflammatory cytokines and oxidized low density lipoproteins increase endothelial cell expression of membrane type 1-matrix metalloproteinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2007.11.020

Activation of PPARalpha or gamma reduces secretion of matrix metalloproteinase 9 but not interleukin 8 from human monocytic THP-1 cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2007.11.020

Antidiabetic PPAR gamma-activator rosiglitazone reduces MMP-9 serum levels in type 2 diabetic patients with coronary artery disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2007.11.020

Liver X receptor-dependent repression of matrix metalloproteinase-9 expression in macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2007.11.020

Gene expression changes in foam cells and the role of chemokine receptor CCR7 during atherosclerosis regression in ApoE-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2007.11.020

Natural killer T cells accelerate atherogenesis in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2007.11.020

CD1d-dependent activation of NKT cells aggravates atherosclerosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2007.11.020

PPAR-gamma agonists inhibit toll-like receptor-mediated activation of dendritic cells via the MAP kinase and NF-kappaB pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2007.11.020

PPARgamma controls CD1d expression by turning on retinoic acid synthesis in developing human dendritic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2007.11.020

Liver X receptors regulate dendritic cell phenotype and function through blocked induction of the actin-bundling protein fascin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2007.11.020

Impaired regulatory T-cell response and enhanced atherosclerosis in the absence of inducible costimulatory molecule.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2007.11.020

Effect of Rosiglitazone on the Risk of Myocardial Infarction and Death from Cardiovascular Causes

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2007.11.020

Natural regulatory T cells control the development of atherosclerosis in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2007.11.020

A role for macrophage scavenger receptors in atherosclerosis and susceptibility to infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2007.11.020