Visualizing the effects of antigen affinity on T-dependent B-cell differentiation (Q37008253)

17 August 2017

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title

Visualizing the effects of antigen affinity on T-dependent B-cell differentiation (English)

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17 August 2017

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Robert Brink

1

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17 August 2017

Tri Giang Phan

series ordinal

2

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17 August 2017

Didrik Paus

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3

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17 August 2017

Tyani D Chan

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4

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17 August 2017

20 November 2007

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Immunology & Cell Biology

17 August 2017

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17 August 2017

86

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17 August 2017

31-39

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17 August 2017

1

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The clonal selection theory: 50 years since the revolution

17 August 2017

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https://api.crossref.org/works/10.1038%2FSJ.ICB.7100143

Transgenic mice and analysis of B-cell tolerance

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ICB.7100143

Altered immunoglobulin expression and functional silencing of self-reactive B lymphocytes in transgenic mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100143

Elimination from peripheral lymphoid tissues of self-reactive B lymphocytes recognizing membrane-bound antigens

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ICB.7100143

Predominant autoantibody production by early human B cell precursors

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ICB.7100143

Regulation of B cell self-tolerance by BAFF

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ICB.7100143

Targeted insertion of a variable region gene into the immunoglobulin heavy chain locus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100143

Rearrangement of upstream DH and VH genes to a rearranged immunoglobulin variable region gene inserted into the DQ52-JH region of the immunoglobulin heavy chain locus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100143

21 January 2018

A quasi-monoclonal mouse

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https://api.crossref.org/works/10.1038%2FSJ.ICB.7100143

Affinity dependence of the B cell response to antigen: a threshold, a ceiling, and the importance of off-rate

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ICB.7100143

Very low affinity B cells form germinal centers, become memory B cells, and participate in secondary immune responses when higher affinity competition is reduced

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ICB.7100143

Intraclonal generation of antibody mutants in germinal centres

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ICB.7100143

Maturation of the immune response in germinal centers

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ICB.7100143

In vivo imaging of germinal centres reveals a dynamic open structure

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ICB.7100143

Early high-affinity neutralizing anti-viral IgG responses without further overall improvements of affinity

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ICB.7100143

Kinetic and affinity limits on antibodies produced during immune responses

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ICB.7100143

The extent of affinity maturation differs between the memory and antibody-forming cell compartments in the primary immune response

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100143

bcl-2 transgene expression inhibits apoptosis in the germinal center and reveals differences in the selection of memory B cells and bone marrow antibody-forming cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100143

Fas is required for clonal selection in germinal centers and the subsequent establishment of the memory B cell repertoire.

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ICB.7100143

Role of antigen receptor affinity in T cell-independent antibody responses in vivo

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ICB.7100143

Antigens varying in affinity for the B cell receptor induce differential B lymphocyte responses.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100143

The Cellular Location of Self-antigen Determines the Positive and Negative Selection of Autoreactive B Cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100143

B cell receptor-independent stimuli trigger immunoglobulin (Ig) class switch recombination and production of IgG autoantibodies by anergic self-reactive B cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100143

High affinity germinal center B cells are actively selected into the plasma cell compartment.

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ICB.7100143

Antigen recognition strength regulates the choice between extrafollicular plasma cell and germinal center B cell differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100143

Structure of an antibody-antigen complex: crystal structure of the HyHEL-10 Fab-lysozyme complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100143

Kinetic epitope mapping of the chicken lysozyme.HyHEL-10 Fab complex: delineation of docking trajectories

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100143

The choice of T-cell epitopes utilized on a protein antigen depends on multiple factors distant from, as well as at the determinant site

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100143

Imprinting the fate of antigen-reactive B cells through the affinity of the B cell receptor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100143

Plasma cell ontogeny defined by quantitative changes in blimp-1 expression

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ICB.7100143

Evidence from the generation of immunoglobulin G-secreting cells that stochastic mechanisms regulate lymphocyte differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100143

Intrinsic constraint on plasmablast growth and extrinsic limits of plasma cell survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100143

Generation of migratory antigen-specific plasma blasts and mobilization of resident plasma cells in a secondary immune response.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100143

Imaging of germinal center selection events during affinity maturation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100143

Definition of germinal-center B cell migration in vivo reveals predominant intrazonal circulation patterns.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100143

One cell-one antibody: prelude and aftermath

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100143

7 January 2021

Development and follicular localization of tolerant B lymphocytes in lysozyme/anti-lysozyme IgM/IgD transgenic mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100143

7 January 2021

Immunoglobulin heavy chain gene replacement: a mechanism of receptor editing

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100143

7 January 2021

Cell Selection by Antigen in the Immune Response

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https://api.crossref.org/works/10.1038%2FSJ.ICB.7100143

7 January 2021

Role of BCR affinity in T cell dependent antibody responses in vivo

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100143

7 January 2021

Altered migration, recruitment, and somatic hypermutation in the early response of marginal zone B cells to T cell-dependent antigen

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB.7100143

7 January 2021

Identifiers

DOI

10.1038/SJ.ICB.7100143

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17 August 2017

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