Imprinting the fate of antigen-reactive B cells through the affinity of the B cell receptor. (Q30437109)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17114443%20AND%20SRC:MED&resulttype=core&format=json

22 December 2019

title

Imprinting the fate of antigen-reactive B cells through the affinity of the B cell receptor (English)

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22 December 2019

2

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22 December 2019

author name string

Brian P O'Connor

1

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22 December 2019

Weijun Zhang

3

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22 December 2019

William Loo

4

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22 December 2019

Danielle Shnider

5

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22 December 2019

Evan F Lind

6

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22 December 2019

Michelle Ratliff

7

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22 December 2019

Randolph J Noelle

8

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22 December 2019

Loren D Erickson

9

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22 December 2019

language of work or name

English

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publication date

1 December 2006

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22 December 2019

published in

Journal of Immunology

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22 December 2019

volume

177

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22 December 2019

issue

11

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22 December 2019

page(s)

7723-7732

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Antigen recognition strength regulates the choice between extrafollicular plasma cell and germinal center B cell differentiation

22 December 2019

cites work

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Memory B cells without somatic hypermutation are generated from Bcl6-deficient B cells

14 July 2018

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14 July 2018

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Very low affinity B cells form germinal centers, become memory B cells, and participate in secondary immune responses when higher affinity competition is reduced

14 July 2018

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14 July 2018

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Two new isotype-specific switching activities detected for Ig class switching

14 July 2018

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Short-circuiting long-lived humoral immunity by the heightened engagement of CD40.

14 July 2018

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XBP1 mRNA is induced by ATF6 and spliced by IRE1 in response to ER stress to produce a highly active transcription factor

14 July 2018

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14 July 2018

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Plasma cell differentiation requires the transcription factor XBP-1

14 July 2018

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B cell immunopoiesis: visualizing the impact of CD40 engagement on the course of T cell-independent immune responses in an Ig transgenic system

14 July 2018

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Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme

14 July 2018

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Evidence for class-specific factors in immunoglobulin isotype switching

14 July 2018

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A monoclonal antibody (MUM1p) detects expression of the MUM1/IRF4 protein in a subset of germinal center B cells, plasma cells, and activated T cells

14 July 2018

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bcl-2 transgene expression inhibits apoptosis in the germinal center and reveals differences in the selection of memory B cells and bone marrow antibody-forming cells

14 July 2018

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Commitment to the B-lymphoid lineage depends on the transcription factor Pax5

14 July 2018

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Antigens varying in affinity for the B cell receptor induce differential B lymphocyte responses.

14 July 2018

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Disruption of the Bcl6 gene results in an impaired germinal center formation

14 July 2018

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The extent of affinity maturation differs between the memory and antibody-forming cell compartments in the primary immune response

14 July 2018

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The BCL-6 proto-oncogene controls germinal-centre formation and Th2-type inflammation

14 July 2018

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Control of inflammation, cytokine expression, and germinal center formation by BCL-6

14 July 2018

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14 July 2018

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14 July 2018

A quasi-monoclonal mouse

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In situ studies of the germinal center reaction

14 July 2018

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Peripheral B cell maturation. II. Heat-stable antigen(hi) splenic B cells are an immature developmental intermediate in the production of long-lived marrow-derived B cells

14 July 2018

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In situ studies of the primary immune response to (4-hydroxy-3-nitrophenyl)acetyl. III. The kinetics of V region mutation and selection in germinal center B cells

14 July 2018

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The bone marrow of multiple myeloma patients contains B cell populations at different stages of differentiation that are clonally related to the malignant plasma cell

14 July 2018

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14 July 2018

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Generation of antibody diversity in the immune response of BALB/c mice to influenza virus hemagglutinin

14 July 2018

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Clonal recruitment and somatic mutation in the generation of immunological memory to the hapten NP

14 July 2018

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V region gene usage and somatic mutation in the primary and secondary responses to influenza virus hemagglutinin.

14 July 2018

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Intraclonal generation of antibody mutants in germinal centres

14 July 2018

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In situ studies of the primary immune response to (4-hydroxy-3-nitrophenyl)acetyl. I. The architecture and dynamics of responding cell populations

14 July 2018

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Maturation of the immune response in germinal centers

14 July 2018

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Analysis of marginal zone B cell development in the mouse with limited B cell diversity: role of the antigen receptor signals in the recruitment of B cells to the marginal zone.

14 July 2018

1 reference

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Blimp-1 Is Required for the Formation of Immunoglobulin Secreting Plasma Cells and Pre-Plasma Memory B Cells

26 November 2018

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B cell selection and affinity maturation during an antibody response in the mouse with limited B cell diversity.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2819292

Reversion of B cell commitment upon loss of Pax5 expression

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2819292

Role of antigen receptor affinity in T cell-independent antibody responses in vivo

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2819292

Low-level hypermutation in T cell-independent germinal centers compared with high mutation rates associated with T cell-dependent germinal centers

26 November 2018

1 reference

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Marginal zone and B1 B cells unite in the early response against T-independent blood-borne particulate antigens

26 November 2018

1 reference

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Dissecting affinity maturation: a model explaining selection of antibody-forming cells and memory B cells in the germinal centre.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2819292

Relaxed negative selection in germinal centers and impaired affinity maturation in bcl-xL transgenic mice

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2819292

In situ studies of the primary immune response to (4-hydroxy-3-nitrophenyl)acetyl. V. Affinity maturation develops in two stages of clonal selection.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2819292

Marginal zone B cells exhibit unique activation, proliferative and immunoglobulin secretory responses.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2819292

The proliferative potential of myeloma plasma cells manifest in the SCID-hu host

26 November 2018

1 reference

12 December 2020

B cells from p50/NF-kappa B knockout mice have selective defects in proliferation, differentiation, germ-line CH transcription, and Ig class switching

1 reference

12 December 2020

Role of BCR affinity in T cell dependent antibody responses in vivo

1 reference

12 December 2020

Clonotypic myeloma cells able to xenograft myeloma to nonobese diabetic severe combined immunodeficient mice copurify with CD34 (+) hematopoietic progenitors

1 reference

12 December 2020

Direct measurement of antibody affinity distribution by hapten-inhibition enzyme immunoassay

1 reference

12 December 2020

Somatic mutation and the maturation of immune response to 2-phenyl oxazolone

1 reference

12 December 2020

B cells genetically deficient in the c-Rel transactivation domain have selective defects in germline CH transcription and Ig class switching

1 reference

12 December 2020

Antigen drives very low affinity B cells to become plasmacytes and enter germinal centers

1 reference

12 December 2020

10.4049/JIMMUNOL.177.11.7723

Identifiers

DOI

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22 December 2019

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22 December 2019

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