Drug transport across the placenta, role of the ABC drug efflux transporters (Q37008886)

17 August 2017

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title

Drug transport across the placenta, role of the ABC drug efflux transporters (English)

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17 August 2017

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Javad Behravan

1

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17 August 2017

Micheline Piquette-Miller

series ordinal

2

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17 August 2017

language of work or name

English

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publication date

1 December 2007

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Expert Opinion on Drug Metabolism & Toxicology

17 August 2017

published in

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17 August 2017

volume

3

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17 August 2017

issue

6

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17 August 2017

page(s)

819-830

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Transport of glyburide by placental ABC transporters: implications in fetal drug exposure.

17 August 2017

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Syncytiotrophoblast is a barrier to maternal-fetal transmission of herpes simplex virus

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Mechanisms of chloride transport across the syncytiotrophoblast basal membrane in the human placenta

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Expression, localization, and function of MRP5 (ABCC5), a transporter for cyclic nucleotides, in human placenta and cultured human trophoblasts: effects of gestational age and cellular differentiation

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Conditionally immortalized syncytiotrophoblast cell lines as new tools for study of the blood-placenta barrier

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Human placental trophoblast culture: One-sided and two-sided models

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Culture of syncytiotrophoblast for the study of human placental transfer. Part II: Production, culture and use of syncytiotrophoblast

21 January 2018

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21 January 2018

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21 January 2018

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Cellular localization of the multidrug-resistance gene product P-glycoprotein in normal human tissues

21 January 2018

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Functional expression and localization of P-glycoprotein at the blood brain barrier

21 January 2018

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Expression of P-glycoprotein in human cerebral cortex microvessels

21 January 2018

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P-glycoprotein and breast cancer resistance protein expression in human placentae of various gestational ages

21 January 2018

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Role of MDR1 and MRP1 in trophoblast cells, elucidated using retroviral gene transfer

21 January 2018

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21 January 2018

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Normal viability and altered pharmacokinetics in mice lacking mdr1-type (drug-transporting) P-glycoproteins

21 January 2018

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Placental P-glycoprotein deficiency enhances susceptibility to chemically induced birth defects in mice

21 January 2018

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P-glycoprotein deficiency in a subpopulation of CF-1 mice enhances avermectin-induced neurotoxicity

21 January 2018

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Disruption of the mouse mdr1a P-glycoprotein gene leads to a deficiency in the blood-brain barrier and to increased sensitivity to drugs

21 January 2018

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21 January 2018

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21 January 2018

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Human placental transport of vinblastine, vincristine, digoxin and progesterone: contribution of P-glycoprotein.

21 January 2018

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21 January 2018

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Explaining interindividual variability of docetaxel pharmacokinetics and pharmacodynamics in Asians through phenotyping and genotyping strategies

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Overexpression of a transporter gene in a multidrug-resistant human lung cancer cell line

21 January 2018

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Multidrug resistance proteins: role of P-glycoprotein, MRP1, MRP2, and BCRP (ABCG2) in tissue defense

21 January 2018

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Folate concentration dependent transport activity of the Multidrug Resistance Protein 1 (ABCC1).

21 January 2018

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Folate deprivation results in the loss of breast cancer resistance protein (BCRP/ABCG2) expression. A role for BCRP in cellular folate homeostasis

21 January 2018

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Transport function and substrate specificity of multidrug resistance protein

21 January 2018

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ATP-dependent transport of bilirubin glucuronides by the multidrug resistance protein MRP1 and its hepatocyte canalicular isoform MRP2.

21 January 2018

1 reference

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Arsenic transport by the human multidrug resistance protein 1 (MRP1/ABCC1). Evidence that a tri-glutathione conjugate is required

21 January 2018

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Toxicological relevance of the multidrug resistance protein 1, MRP1 (ABCC1) and related transporters.

21 January 2018

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A mutation in the human canalicular multispecific organic anion transporter gene causes the Dubin-Johnson syndrome

21 January 2018

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The canalicular multispecific organic anion transporter and conjugated hyperbilirubinemia in rat and man.

21 January 2018

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Variable expression of MRP2 (ABCC2) in human placenta: influence of gestational age and cellular differentiation.

21 January 2018

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A family of drug transporters: the multidrug resistance-associated proteins.

21 January 2018

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21 January 2018

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Characterization of the transport properties of cloned rat multidrug resistance-associated protein 3 (MRP3).

21 January 2018

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Tissue distribution and induction of human multidrug resistant protein 3

21 January 2018

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MRP3, an organic anion transporter able to transport anti-cancer drugs

21 January 2018

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Thiopurine metabolism and identification of the thiopurine metabolites transported by MRP4 and MRP5 overexpressed in human embryonic kidney cells.

21 January 2018

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Multidrug-resistance protein 5 is a multispecific organic anion transporter able to transport nucleotide analogs

21 January 2018

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Multidrug resistance protein 4 (MRP4/ABCC4) mediates efflux of bimane-glutathione.

21 January 2018

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Role of glutathione in the multidrug resistance protein 4 (MRP4/ABCC4)-mediated efflux of cAMP and resistance to purine analogues

21 January 2018

1 reference

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Analysis of the structure and expression pattern of MRP7 (ABCC10), a new member of the MRP subfamily

21 January 2018

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Analysis of the drug resistance profile of multidrug resistance protein 7 (ABCC10): resistance to docetaxel

21 January 2018

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A multidrug resistance transporter from human MCF-7 breast cancer cells

21 January 2018

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Multidrug resistance mediated by the breast cancer resistance protein BCRP (ABCG2)

21 January 2018

1 reference

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Characterization of oligomeric human half-ABC transporter ATP-binding cassette G2.

21 January 2018

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The stem cell marker Bcrp/ABCG2 enhances hypoxic cell survival through interactions with heme

21 January 2018

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Bcrp1 gene expression is required for normal numbers of side population stem cells in mice, and confers relative protection to mitoxantrone in hematopoietic cells in vivo

21 January 2018

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Stage-specific distribution of P-glycoprotein in first-trimester and full-term human placenta.

21 January 2018

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Effects of maturation on RNA transcription and protein expression of four MRP genes in human placenta and in BeWo cells

21 January 2018

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Expression level of ABCG2 in the placenta decreases from the mid stage to the end of gestation

21 January 2018

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Lipopolysaccharide treatment downregulates the expression of the pregnane X receptor, cyp3a11 and mdr1a genes in mouse placenta

21 January 2018

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TNF-alpha is a predictor of insulin resistance in human pregnancy

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.3.6.819

Functional assessment of ABCG2 (BCRP) gene polymorphisms to protein expression in human placenta.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.3.6.819

Multidrug resistance phosphoglycoprotein (ABCB1) in the mouse placenta: fetal protection

21 January 2018

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Estrogen-mediated post transcriptional down-regulation of P-glycoprotein in MDR1-transduced human breast cancer cells.

21 January 2018

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Breast cancer resistance protein (Bcrp1/Abcg2) in mouse placenta and yolk sac: ontogeny and its regulation by progesterone

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.3.6.819

The functions and structure of ABC transporters: implications for the design of new inhibitors of Pgp and MRP1 to control multidrug resistance (MDR).

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.3.6.819

Transplacental treatment of fetal tachycardia: implications of drug transporting proteins in placenta

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.3.6.819

Rapid Identification of P-glycoprotein Substrates and Inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.3.6.819

21 January 2018

Identifiers

DOI

10.1517/17425255.3.6.819

1 reference

17 August 2017

1 reference