Polyglutamine disease toxicity is regulated by Nemo-like kinase in spinocerebellar ataxia type 1. (Q37009447)

17 August 2017

Polyglutamine disease toxicity is regulated by Nemo-like kinase in spinocerebellar ataxia type 1. (English)

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17 August 2017

spinocerebellar ataxia

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Hyoungseok Ju

1

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Harry T. Orr

object named as

Harry T Orr

8

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Huda Zoghbi

object named as

Huda Y Zoghbi

9

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author name string

Hiroshi Kokubu

2

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17 August 2017

Tiffany W Todd

3

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17 August 2017

Juliette J Kahle

4

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17 August 2017

Soeun Kim

5

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17 August 2017

Ronald Richman

6

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17 August 2017

Karthik Chirala

7

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17 August 2017

Janghoo Lim

10

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17 August 2017

language of work or name

English

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publication date

1 May 2013

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17 August 2017

Journal of Neuroscience

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17 August 2017

33

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17 August 2017

22

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17 August 2017

9328-9336

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describes a project that uses

17 August 2017

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3710458/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

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ATXN1 protein family and CIC regulate extracellular matrix remodeling and lung alveolarization

29 September 2017

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Vascular endothelial growth factor ameliorates the ataxic phenotype in a mouse model of spinocerebellar ataxia type 1.

29 September 2017

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Regional rescue of spinocerebellar ataxia type 1 phenotypes by 14-3-3epsilon haploinsufficiency in mice underscores complex pathogenicity in neurodegeneration

29 September 2017

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29 September 2017

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SCA1-like disease in mice expressing wild-type ataxin-1 with a serine to aspartic acid replacement at residue 776.

29 September 2017

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Partial loss of ataxin-1 function contributes to transcriptional dysregulation in spinocerebellar ataxia type 1 pathogenesis

29 September 2017

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29 September 2017

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29 September 2017

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Opposing effects of polyglutamine expansion on native protein complexes contribute to SCA1

29 September 2017

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The role of LANP and ataxin 1 in E4F-mediated transcriptional repression

29 September 2017

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Trinucleotide Repeat Disorders

29 September 2017

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29 September 2017

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A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration

29 September 2017

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Identification of a novel phosphorylation site in ataxin-1.

29 September 2017

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Regulation of lymphoid enhancer factor 1/T-cell factor by mitogen-activated protein kinase-related Nemo-like kinase-dependent phosphorylation in Wnt/beta-catenin signaling

29 September 2017

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Polyglutamine pathogenesis: emergence of unifying mechanisms for Huntington's disease and related disorders

29 September 2017

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Polyglutamine expansion down-regulates specific neuronal genes before pathologic changes in SCA1.

29 September 2017

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MAP kinase and Wnt pathways converge to downregulate an HMG-domain repressor in Caenorhabditis elegans

29 September 2017

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WRM-1 activates the LIT-1 protein kinase to transduce anterior/posterior polarity signals in C. elegans

29 September 2017

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Nlk is a murine protein kinase related to Erk/MAP kinases and localized in the nucleus

29 September 2017

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29 September 2017

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29 September 2017

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Homodimerization of Nemo-like kinase is essential for activation and nuclear localization

29 September 2017

1 reference

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Duplication of Atxn1l suppresses SCA1 neuropathology by decreasing incorporation of polyglutamine-expanded ataxin-1 into native complexes

27 June 2018

1 reference

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ATAXIN-1 interacts with the repressor Capicua in its native complex to cause SCA1 neuropathology

4 September 2018

1 reference

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Nemo-like kinase (NLK) acts downstream of Notch/Delta signalling to downregulate TCF during mesoderm induction in the sea urchin embryo.

4 September 2018

1 reference

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Gene profiling links SCA1 pathophysiology to glutamate signaling in Purkinje cells of transgenic mice

4 September 2018

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Serine 776 of ataxin-1 is critical for polyglutamine-induced disease in SCA1 transgenic mice

4 September 2018

1 reference

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A long CAG repeat in the mouse Sca1 locus replicates SCA1 features and reveals the impact of protein solubility on selective neurodegeneration.

4 September 2018

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Abnormal bone marrow stroma in mice deficient for nemo-like kinase, Nlk.

4 September 2018

1 reference

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The tissue polarity gene nemo carries out multiple roles in patterning during Drosophila development

4 September 2018

1 reference

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Identification of genes that modify ataxin-1-induced neurodegeneration.

4 September 2018

1 reference

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The TAK1-NLK-MAPK-related pathway antagonizes signalling between beta-catenin and transcription factor TCF.

4 September 2018

1 reference

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Rotation of photoreceptor clusters in the developing Drosophila eye requires the nemo gene

4 September 2018

1 reference

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10.1523/JNEUROSCI.3465-12.2013

4 September 2018

Identifiers

DOI

1 reference

17 August 2017

1 reference

17 August 2017

PubMed publication ID

23719801

1 reference