Imidazenil: a low efficacy agonist at alpha1- but high efficacy at alpha5-GABAA receptors fail to show anticonvulsant cross tolerance to diazepam or zolpidem (Q37012643)

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scientific article published on 09 May 2008

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English	Imidazenil: a low efficacy agonist at alpha1- but high efficacy at alpha5-GABAA receptors fail to show anticonvulsant cross tolerance to diazepam or zolpidem	scientific article published on 09 May 2008

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scholarly article

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9 January 2020

Imidazenil: a low efficacy agonist at alpha1- but high efficacy at alpha5-GABAA receptors fail to show anticonvulsant cross tolerance to diazepam or zolpidem (English)

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9 January 2020

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9 January 2020

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James Auta

1

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9 January 2020

Francesco Impagnatiello

2

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9 January 2020

Alessandro Guidotti

4

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9 January 2020

Erminio Costa

5

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9 January 2020

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9 May 2008

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9 January 2020

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6

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Neuropharmacology

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9 January 2020

55

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9 January 2020

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9 January 2020

148-153

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9 January 2020

Enhanced macroscopic desensitization shapes the response of alpha4 subtype-containing GABAA receptors to synaptic and extrasynaptic GABA

1 reference

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L-655,708 enhances cognition in rats but is not proconvulsant at a dose selective for alpha5-containing GABAA receptors.

1 reference

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GABAA receptor subtypes: any clues to the mechanism of benzodiazepine dependence?

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Contribution of the alpha1-GABA(A) receptor subtype to the pharmacological actions of benzodiazepine site inverse agonists

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Trace fear conditioning involves hippocampal alpha5 GABA(A) receptors

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Basic pharmacologic mechanisms involved in benzodiazepine tolerance and withdrawal

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Molecular targets for the myorelaxant action of diazepam.

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Mechanism of action of the hypnotic zolpidem in vivo

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Sedative but not anxiolytic properties of benzodiazepines are mediated by the GABA(A) receptor alpha1 subtype.

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Imidazenil prevention of alprazolam-induced acquisition deficit in patas monkeys is devoid of tolerance

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[3H]L-655,708, a novel ligand selective for the benzodiazepine site of GABAA receptors which contain the alpha 5 subunit

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Pharmacological modulation of the diazepam-insensitive recombinant gamma-aminobutyric acidA receptors alpha 4 beta 2 gamma 2 and alpha 6 beta 2 gamma 2

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Modifications of gamma-aminobutyric acidA receptor subunit expression in rat neocortex during tolerance to diazepam.

1 reference

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Imidazenil, a partial positive allosteric modulator of GABAA receptors, exhibits low tolerance and dependence liabilities in the rat

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1 reference

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12 December 2020

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10.1016/J.NEUROPHARM.2008.05.002

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9 January 2020

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9 January 2020

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9 January 2020

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