Local anesthetics disrupt energetic coupling between the voltage-sensing segments of a sodium channel. (Q37023303)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19088384%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

title

Local anesthetics disrupt energetic coupling between the voltage-sensing segments of a sodium channel (English)

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18 January 2020

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2

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18 January 2020

author name string

Yukiko Muroi

series ordinal

1

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18 January 2020

publication date

15 December 2008

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The Journal of General Physiology

18 January 2020

published in

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18 January 2020

volume

133

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18 January 2020

issue

1

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18 January 2020

page(s)

1-15

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Alpha-scorpion toxin impairs a conformational change that leads to fast inactivation of muscle sodium channels

18 January 2020

cites work

1 reference

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beta-Scorpion toxin modifies gating transitions in all four voltage sensors of the sodium channel

29 September 2017

1 reference

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Binding of a gating modifier toxin induces intersubunit cooperativity early in the Shaker K channel's activation pathway

29 September 2017

1 reference

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The cooperative voltage sensor motion that gates a potassium channel

29 September 2017

1 reference

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Coupling interactions between voltage sensors of the sodium channel as revealed by site-specific measurements

29 September 2017

1 reference

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Molecular action of lidocaine on the voltage sensors of sodium channels

29 September 2017

1 reference

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Tracking voltage-dependent conformational changes in skeletal muscle sodium channel during activation.

29 September 2017

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Tight steric closure at the intracellular activation gate of a voltage-gated K(+) channel

29 September 2017

1 reference

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Immobilizing the moving parts of voltage-gated ion channels

29 September 2017

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Lidocaine alters activation gating of cardiac Na channels

29 September 2017

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Independence and cooperativity in rearrangements of a potassium channel voltage sensor revealed by single subunit fluorescence

29 September 2017

1 reference

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Intrinsic lidocaine affinity for Na channels expressed in Xenopus oocytes depends on alpha (hH1 vs. rSkM1) and beta 1 subunits

29 September 2017

1 reference

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Mutations in the S4 region isolate the final voltage-dependent cooperative step in potassium channel activation

29 September 2017

1 reference

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The position of the fast-inactivation gate during lidocaine block of voltage-gated Na+ channels

29 September 2017

1 reference

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Structural implications of fluorescence quenching in the Shaker K+ channel

29 September 2017

1 reference

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The Structure of the Potassium Channel: Molecular Basis of K+ Conduction and Selectivity

29 September 2017

1 reference

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Uncharged S4 residues and cooperativity in voltage-dependent potassium channel activation

29 September 2017

1 reference

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Role of the S4 in cooperativity of voltage-dependent potassium channel activation

29 September 2017

1 reference

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A unique role for the S4 segment of domain 4 in the inactivation of sodium channels

29 September 2017

1 reference

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Common molecular determinants of local anesthetic, antiarrhythmic, and anticonvulsant block of voltage-gated Na+ channels

29 September 2017

1 reference

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Voltage-dependent open-state inactivation of cardiac sodium channels: gating current studies with Anthopleurin-A toxin

29 September 2017

1 reference

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Modification of inactivation in cardiac sodium channels: ionic current studies with Anthopleurin-A toxin

29 September 2017

1 reference

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Shaker potassium channel gating. III: Evaluation of kinetic models for activation

29 September 2017

1 reference

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Kinetic effects of quaternary lidocaine block of cardiac sodium channels: a gating current study

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2606943

Local anesthetic block of sodium channels in normal and pronase-treated squid giant axons

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2606943

Local anesthetics: hydrophilic and hydrophobic pathways for the drug-receptor reaction

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2606943

Interactions between quaternary lidocaine, the sodium channel gates, and tetrodotoxin

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2606943

Local anesthetics. Effect of pH on use-dependent block of sodium channels in frog muscle

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2606943

The open pore conformation of potassium channels

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2606943

Interaction of Tetraethylammonium Ion Derivatives with the Potassium Channels of Giant Axons

27 June 2018

1 reference

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The Inhibition of Sodium Currents in Myelinated Nerve by Quaternary Derivatives of Lidocaine

27 June 2018

1 reference

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The inner quaternary ammonium ion receptor in potassium channels of the node of Ranvier

27 June 2018

1 reference

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Molecular basis of gating charge immobilization in Shaker potassium channels.

27 June 2018

1 reference

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The penetration of local anesthetics into the red blood cell membrane as studied by fluorescence quenching

27 June 2018

1 reference

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Electrostatic contributions of aromatic residues in the local anesthetic receptor of voltage-gated sodium channels

27 June 2018

1 reference

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Molecular modeling of local anesthetic drug binding by voltage-gated sodium channels

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2606943

Intermolecular electron transfer between coumarin dyes and aromatic amines in Triton-X-100 micellar solutions: evidence for Marcus inverted region.

4 September 2018

1 reference

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Role of amino acid residues in transmembrane segments IS6 and IIS6 of the Na+ channel alpha subunit in voltage-dependent gating and drug block.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2606943

Disparate role of Na(+) channel D2-S6 residues in batrachotoxin and local anesthetic action

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2606943

Molecular determinants of voltage-dependent gating and binding of pore-blocking drugs in transmembrane segment IIIS6 of the Na(+) channel alpha subunit.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2606943

Direct physical measure of conformational rearrangement underlying potassium channel gating

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2606943

Molecular determinants of state-dependent block of Na+ channels by local anesthetics

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2606943

Energetics of pore opening in a voltage-gated K(+) channel

4 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19088384

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1085/JGP.200810103

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19088384%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19088384%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

1 reference