Mechanistic role of calpains in postischemic neurodegeneration (Q37029897)

17 August 2017

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title

Mechanistic role of calpains in postischemic neurodegeneration (English)

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17 August 2017

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Matthew B Bevers

1

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17 August 2017

Robert W Neumar

series ordinal

2

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17 August 2017

publication date

12 December 2007

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Journal of Cerebral Blood Flow & Metabolism

17 August 2017

published in

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17 August 2017

volume

28

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17 August 2017

issue

4

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17 August 2017

page(s)

655-673

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NMDA-receptor activation induces calpain-mediated beta-catenin cleavages for triggering gene expression.

17 August 2017

cites work

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21 January 2018

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Disruption of the mouse mu-calpain gene reveals an essential role in platelet function

21 January 2018

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Cleavage of the plasma membrane Na+/Ca2+ exchanger in excitotoxicity

21 January 2018

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Postischemic administration of AK275, a calpain inhibitor, provides substantial protection against focal ischemic brain damage

21 January 2018

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Temporal ordering of pathogenic events following transient global ischemia

21 January 2018

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Translational suppression of calpain I reduces NMDA-induced spectrin proteolysis and pathophysiology in cultured hippocampal slices

21 January 2018

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Spectrin-based membrane skeleton: a multipotential adaptor between plasma membrane and cytoplasm

21 January 2018

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Bell-shaped calcium-response curves of Ins(1,4,5)P3- and calcium-gated channels from endoplasmic reticulum of cerebellum

21 January 2018

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Calpain-mediated proteolysis of GluR1 subunits in organotypic hippocampal cultures following kainic acid treatment.

21 January 2018

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Synergistic activation of caspase-3 by m-calpain after neonatal hypoxia-ischemia: a mechanism of "pathological apoptosis"?

21 January 2018

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Microtubule-associated protein 2 (MAP2) associates with the NMDA receptor and is spatially redistributed within rat hippocampal neurons after oxygen-glucose deprivation.

21 January 2018

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Critical role of calpain I in mitochondrial release of apoptosis-inducing factor in ischemic neuronal injury.

21 January 2018

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Bid is cleaved by calpain to an active fragment in vitro and during myocardial ischemia/reperfusion

21 January 2018

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Cleavage of Bax is mediated by caspase-dependent or -independent calpain activation in dopaminergic neuronal cells: protective role of Bcl-2.

21 January 2018

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Direct cleavage by the calcium-activated protease calpain can lead to inactivation of caspases

21 January 2018

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Determination of peptide substrate specificity for mu-calpain by a peptide library-based approach: the importance of primed side interactions

21 January 2018

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Spectrin and calpain: a 'target' and a 'sniper' in the pathology of neuronal cells.

21 January 2018

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The MAP2/Tau family of microtubule-associated proteins

21 January 2018

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Proteolysis of the protein inhibitor of calcium-dependent proteases produces lower molecular weight fragments that retain inhibitory activity

21 January 2018

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21 January 2018

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Interactions of postsynaptic density-95 and the NMDA receptor 2 subunit control calpain-mediated cleavage of the NMDA receptor.

21 January 2018

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Developmental and cell-selective variations in N-methyl-D-aspartate receptor degradation by calpain

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600595

A survey of calpain inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600595

m-Calpain is required for preimplantation embryonic development in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600595

Poly(ADP-ribose) polymerase gene disruption renders mice resistant to cerebral ischemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600595

Ischemia-induced increase in long-term potentiation is warded off by specific calpain inhibitor PD150606.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600595

Inositol 1,4,5-Trisphosphate-Activated Calcium Channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600595

Isoform specific function of calpain 2 in regulating membrane protrusion

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600595

Ischemia-reperfusion-induced calpain activation and SERCA2a degradation are attenuated by exercise training and calpain inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600595

Differential distribution of calpain small subunit 1 and 2 in rat brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600595

Immunohistochemical distribution of calcium-activated neutral proteinases and endogenous CANP inhibitor in the rabbit hippocampus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600595

Mitochondrial localization of mu-calpain

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600595

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600595

N-terminal cleavage of GSK-3 by calpain: a new form of GSK-3 regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600595

Lack of phenotype for LTP and fear conditioning learning in calpain 1 knock-out mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600595

Specific proteolysis of the NR2 subunit at multiple sites by calpain

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600595

Proteolysis of the N-methyl-d-aspartate receptor by calpain in situ

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600595

Hydroxyl radical production and lipid peroxidation parallels selective post-ischemic vulnerability in gerbil brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600595

N-methyl-D-aspartate receptor-induced proteolytic conversion of postsynaptic class C L-type calcium channels in hippocampal neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600595

Expression and functional characteristics of calpain 3 isoforms generated through tissue-specific transcriptional and posttranscriptional events

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600595

Selective coupling of mu-calpain activation with the NMDA receptor is independent of translocation and autolysis in primary cortical neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600595

Distinct mechanistic roles of calpain and caspase activation in neurodegeneration as revealed in mice overexpressing their specific inhibitors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600595

Activation of m-calpain is required for chromosome alignment on the metaphase plate during mitosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600595

Calcium-activated proteolysis in rat neocortex induced by transient focal ischemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600595

Differential compartmentalization of the calpain/calpastatin network with the endoplasmic reticulum and Golgi apparatus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600595

Association of the calpain/calpastatin network with subcellular organelles

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600595

Crystal structure of calpain reveals the structural basis for Ca(2+)-dependent protease activity and a novel mode of enzyme activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600595

Calpain-cleaved collapsin response mediator protein-3 induces neuronal death after glutamate toxicity and cerebral ischemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600595

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600595

Structure-activity relationship study and drug profile of N-(4-fluorophenylsulfonyl)-L-valyl-L-leucinal (SJA6017) as a potent calpain inhibitor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600595

Suppressive effect of E-64c on ischemic degradation of cerebral proteins following occlusion of the middle cerebral artery in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600595

The inositol tris/tetrakisphosphate pathway--demonstration of Ins(1,4,5)P3 3-kinase activity in animal tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600595

Prolonged positive modulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors induces calpain-mediated PSD-95/Dlg/ZO-1 protein degradation and AMPA receptor down-regulation in cultured hippocampal slices

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600595

Calpain 3 is expressed in astrocytes of rat and Microcebus brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600595

The novel calpain inhibitor SJA6017 improves functional outcome after delayed administration in a mouse model of diffuse brain injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600595

Inhibition of proteolysis protects hippocampal neurons from ischemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600595

Neurotoxicity induces cleavage of p35 to p25 by calpain

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600595

Distribution of plasma membrane Ca2+ pump (PMCA) isoforms in the gerbil brain: effect of ischemia-reperfusion injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600595

Postischemic treatment with calpain inhibitor MDL 28170 ameliorates brain damage in a gerbil model of global ischemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600595

Effects of transient global ischemia and kainate on poly(ADP-ribose) polymerase (PARP) gene expression and proteolytic cleavage in gerbil and rat brains

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600595

Expression of Ca(2+)-permeable AMPA receptor channels primes cell death in transient forebrain ischemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600595

Calpain-mediated truncation of rat brain AMPA receptors increases their Triton X-100 solubility

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600595

Benzoylalanine-derived ketoamides carrying vinylbenzyl amino residues: discovery of potent water-soluble calpain inhibitors with oral bioavailability

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600595

Characterization and expression of calpain 10. A novel ubiquitous calpain with nuclear localization

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600595

Detection and localization of calpain 3-like protease in a neuronal cell line: possible regulation of apoptotic cell death through degradation of nuclear IkappaBalpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600595

Six-hour window of opportunity for calpain inhibition in focal cerebral ischemia in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600595

Procaspase-3 and poly(ADP)ribose polymerase (PARP) are calpain substrates

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600595

Involvement of micro-calpain (CAPN 1) in muscle cell differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600595

Cross-talk between two cysteine protease families. Activation of caspase-12 by calpain in apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600595

Effects of dantrolene on extracellular glutamate concentration and neuronal death in the rat hippocampal CA1 region subjected to transient ischemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600595

A novel water-soluble and cell-permeable calpain inhibitor protects myocardial and mitochondrial function in postischemic reperfusion

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600595

Calpain activity in the rat brain after transient forebrain ischemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600595

Cross-talk between calpain and caspase proteolytic systems during neuronal apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600595

Role of the ryanodine receptor in ischemic brain damage--localized reduction of ryanodine receptor binding during ischemia in hippocampus CA1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600595

Differential roles of nuclear and cytoplasmic cyclin-dependent kinase 5 in apoptotic and excitotoxic neuronal death

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600595

Histochemical study of Ca(2+)-ATPase activity in ischemic CA1 pyramidal neurons in the gerbil hippocampus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600595

Evolutionary origin of a calcium-dependent protease by fusion of genes for a thiol protease and a calcium-binding protein?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600595

Crystal structure of a micro-like calpain reveals a partially activated conformation with low Ca2+ requirement

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600595

Proteolysis by calpains: a possible contribution to degradation of p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600595

Global ischemia-induced inhibition of the coupling ratio of calcium uptake and ATP hydrolysis by rat whole brain microsomal Mg(2+)/Ca(2+) ATPase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600595

Calpain cleavage of the B isoform of Ins(1,4,5)P3 3-kinase separates the catalytic domain from the membrane anchoring domain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600595

Calpain-mediated cleavage of the cyclin-dependent kinase-5 activator p39 to p29

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600595

The GluR2 (GluR-B) hypothesis: Ca(2+)-permeable AMPA receptors in neurological disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600595

3. Life or death decisions: the cast of poly(ADP-ribose)polymerase (PARP) as a therapeutic target for brain ischaemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600595

Distribution of calcium-activated protease calpain in the rat brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600595

The ultrastructural localization of calcium-activated protease "calpain" in rat brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600595

Microtubular proteolysis in focal cerebral ischemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600595

Mitochondrial generation of reactive oxygen species after brain ischemia in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600595

Calpain I induces cleavage and release of apoptosis-inducing factor from isolated mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600595

Activation of neutrophil calpain following its translocation to the plasma membrane induced by phorbol ester or fMet-Leu-Phe

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600595

Glutamate-induced protease-mediated loss of plasma membrane Ca2+ pump activity in rat hippocampal neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600595

Protective effects of calpain inhibitors against neuronal damage caused by cytotoxic hypoxia in vitro and ischemia in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600595

Digestion of cardiac and skeletal muscle junctional sarcoplasmic reticulum vesicles with calpain II. Effects on the Ca2+ release channel.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600595

Ca(2+)-induced inhibition of apoptosis in human SH-SY5Y neuroblastoma cells: degradation of apoptotic protease activating factor-1 (APAF-1).

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600595

Implication of calpain in caspase activation during B cell clonal deletion

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600595

Apoptosis in retinal degeneration involves cross-talk between apoptosis-inducing factor (AIF) and caspase-12 and is blocked by calpain inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600595

Interferon-inducible protein 9 (CXCL11)-induced cell motility in keratinocytes requires calcium flux-dependent activation of mu-calpain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600595

Tat-calpastatin fusion proteins transduce primary rat cortical neurons but do not inhibit cellular calpain activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600595

Cyclosporin A protects against ischemia-reperfusion injury in the brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600595

Generation of constitutively active calcineurin by calpain contributes to delayed neuronal death following mouse brain ischemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600595

Distribution of calpain I, an enzyme associated with degenerative activity, in rat brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600595

Proteins released from degenerating neurons are surrogate markers for acute brain damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600595

Excitatory amino acids activate calpain I and induce structural protein breakdown in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600595

The crystal structure of calcium-free human m-calpain suggests an electrostatic switch mechanism for activation by calcium

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600595

Specific aspartyl and calpain proteases are required for neurodegeneration in C. elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600595

Calpain mediates excitotoxic DNA fragmentation via mitochondrial pathways in adult brains: evidence from calpastatin mutant mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600595

Proteases involved in long-term potentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600595

On the sequential determinants of calpain cleavage

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600595

Calpain inhibitor (BSF 409425) diminishes ischemia/reperfusion-induced damage of rabbit heart mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600595

Cyclosporin A dramatically ameliorates CA1 hippocampal damage following transient forebrain ischaemia in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600595

Activation of calpain may alter the postsynaptic density structure and modulate anchoring of NMDA receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600595

The critical role of calpain versus caspase activation in excitotoxic injury induced by nitric oxide

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600595

Caspase-mediated fragmentation of calpain inhibitor protein calpastatin during apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600595

Critical role of calpain-mediated cleavage of calcineurin in excitotoxic neurodegeneration.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600595

Regulation of N-methyl-D-aspartate receptors by calpain in cortical neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600595

Calpain-mediated mGluR1alpha truncation: a key step in excitotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600595

Ca2+-dependent proteases in ischemic neuronal death: a conserved 'calpain-cathepsin cascade' from nematodes to primates

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600595

Calpain inhibitor entrapped in liposome rescues ischemic neuronal damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600595

Apoptosis-inducing factor mediates poly(ADP-ribose) (PAR) polymer-induced cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600595

Calpain regulation of AMPA receptor channels in cortical pyramidal neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600595

Specific proteolysis of neuronal protein GAP-43 by calpain: characterization, regulation, and physiological role.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600595

Calpain-mediated collapsin response mediator protein-1, -2, and -4 proteolysis after neurotoxic and traumatic brain injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600595

Decrease of PKC precedes other cellular signs of calpain activation in area CA1 of the hippocampus after transient cerebral ischemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600595

The calpain small subunit gene is essential: its inactivation results in embryonic lethality.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600595

Processing of cdk5 Activator p35 to Its Truncated Form (p25) by Calpain in Acutely Injured Neuronal Cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600595

Calpain inhibitor AK295 protects neurons from focal brain ischemia. Effects of postocclusion intra-arterial administration

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600595

7 January 2021

Delayed antagonism of calpain reduces excitotoxicity in cultured neurons

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600595

7 January 2021

Poly(ADP-ribose) polymerase: early involvement in glutamate-induced neurotoxicity in cultured cerebellar granule cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600595

7 January 2021

Reduced [3H]IP3 binding but unchanged IP3 receptor levels in the rat hippocampus CA1 region following transient global ischemia and tolerance induction

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600595

7 January 2021

Differential proteolysis of the full-length form of the L-type calcium channel alpha 1 subunit by calpain

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600595

7 January 2021

Calpain activation contributes to dendritic remodeling after brief excitotoxic injury in vitro

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600595

7 January 2021

Neuronal nitric oxide synthase and calmodulin-dependent protein kinase IIalpha undergo neurotoxin-induced proteolysis.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600595

7 January 2021

Distribution of calpains I and II in rat brain

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600595

7 January 2021

Calpain-dependent proteolytic cleavage of the p35 cyclin-dependent kinase 5 activator to p25

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600595

7 January 2021

Regional differences in gene expression for calcium activated neutral proteases (calpains) and their endogenous inhibitor calpastatin in mouse brain and spinal cord

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600595

7 January 2021

Calpain-mediated degradation of PSD-95 in developing and adult rat brain

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600595

7 January 2021

All four internally repetitive domains of pig calpastatin possess inhibitory activities against calpains I and II

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600595

7 January 2021

Selective nuclear transport of mu-calpain

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600595

7 January 2021

Alteration of inositol 1,4,5-trisphosphate receptor after six-hour hemispheric ischemia in the gerbil brain

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600595

7 January 2021

Brain mu-calpain autolysis during global cerebral ischemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600595

7 January 2021

Rapid reduction in ryanodine binding of hippocampus CA1 in cerebral ischemia.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600595

7 January 2021

Subcellular distribution of calpain and calpastatin immunoreactivity and fodrin proteolysis in rabbit hippocampus after hypoxia and glucocorticoid treatment

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600595

7 January 2021

Blockade of calpain proteolytic activity rescues neurons from glutamate excitotoxicity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600595

7 January 2021

Immunolocalization of calpain I-mediated spectrin degradation to vulnerable neurons in the ischemic gerbil brain.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600595

7 January 2021

Specificity of calcium-activated neutral proteinase (CANP) inhibitors for human mu CANP and mCANP

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600595

7 January 2021

p25/cyclin-dependent kinase 5 promotes the progression of cell death in nucleus of endoplasmic reticulum-stressed neurons

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600595

7 January 2021

Modulation of calpastatin specificity in rat tissues by reversible phosphorylation and dephosphorylation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600595

7 January 2021

The plasma membrane calcium pump is the preferred calpain substrate within the erythrocyte

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600595

7 January 2021

Selective activation induced cleavage of the NR2B subunit by calpain.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600595

7 January 2021

Calpain inhibitors block Ca(2+)-induced suppression of neurite outgrowth in isolated hippocampal pyramidal neurons

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600595

7 January 2021

Domain III of calpain is a ca2+-regulated phospholipid-binding domain

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600595

7 January 2021

Nuclear calpain regulates Ca2+-dependent signaling via proteolysis of nuclear Ca2+/calmodulin-dependent protein kinase type IV in cultured neurons

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600595

7 January 2021

Functional dissection of human protease mu-calpain in cell migration using RNAi

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600595

7 January 2021

The calcium content of mitochondria from brain subregions following short-term forebrain ischemia and recirculation in the rat.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600595

7 January 2021

Identifiers

DOI

10.1038/SJ.JCBFM.9600595

1 reference

17 August 2017

1 reference