IL10-driven STAT3 signalling in senescent macrophages promotes pathological eye angiogenesis (Q37031844)

17 August 2017

IL10-driven STAT3 signalling in senescent macrophages promotes pathological eye angiogenesis (English)

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17 August 2017

0 references

1 reference

Rei Nakamura

1

1 reference

17 August 2017

Abdoulaye Sene

2

1 reference

17 August 2017

Andrea Santeford

3

1 reference

17 August 2017

Abdelaziz Gdoura

4

1 reference

17 August 2017

Shunsuke Kubota

5

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17 August 2017

Nicole Zapata

6

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17 August 2017

Rajendra S Apte

7

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17 August 2017

language of work or name

English

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publication date

11 August 2015

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17 August 2017

Nature Communications

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17 August 2017

6

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17 August 2017

7847

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Creative Commons Attribution 4.0 International

17 August 2017

start time

11 August 2015

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

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describes a project that uses

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4918330/fullTextXML

inferred from PubMed Central ID database lookup

exact match

https://scigraph.springernature.com/pub.10.1038/ncomms8847

0 references

cites work

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9 September 2017

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Neovascularization in diabetes and its complications. Unraveling the angiogenic paradox.

9 September 2017

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Macrophages are essential for the early wound healing response and the formation of a fibrovascular scar.

9 September 2017

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Impaired cholesterol efflux in senescent macrophages promotes age-related macular degeneration

9 September 2017

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Role of macrophage polarization in tumor angiogenesis and vessel normalization: implications for new anticancer therapies

9 September 2017

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Subretinal drusenoid deposits in non-neovascular age-related macular degeneration: morphology, prevalence, topography, and biogenesis model

9 September 2017

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Cytokine response is determined by duration of receptor and signal transducers and activators of transcription 3 (STAT3) activation

9 September 2017

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Vascular endothelial growth factor a in intraocular vascular disease

9 September 2017

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STAT3 inhibition, a novel approach to enhancing targeted therapy in human cancers (review).

9 September 2017

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SOCS3 is an endogenous inhibitor of pathologic angiogenesis.

9 September 2017

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The Rd8 mutation of the Crb1 gene is present in vendor lines of C57BL/6N mice and embryonic stem cells, and confounds ocular induced mutant phenotypes

9 September 2017

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Non-canonical alternatives: what a macrophage is 4

9 September 2017

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Suppression of cytokine signaling by SOCS3: characterization of the mode of inhibition and the basis of its specificity

9 September 2017

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CD163 and its role in inflammation

9 September 2017

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Basic and therapeutic aspects of angiogenesis

9 September 2017

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Macrophage polarization in the maculae of age-related macular degeneration: a pilot study

9 September 2017

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Signal transducer and activator of transcription 3 in liver diseases: a novel therapeutic target

9 September 2017

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Suppression of choroidal neovascularization by N-acetyl-cysteine in mice

9 September 2017

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Arginine usage in mycobacteria-infected macrophages depends on autocrine-paracrine cytokine signaling

9 September 2017

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Immune infiltration in human cancer: prognostic significance and disease control

9 September 2017

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The regulation of IL-10 production by immune cells

9 September 2017

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Therapeutic targeting of myeloid-derived suppressor cells

9 September 2017

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Novel high-throughput screening system for identifying STAT3-SH2 antagonists

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4918330

Exploring the full spectrum of macrophage activation

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4918330

Effect of bevacizumab on inflammation and proliferation in human choroidal neovascularization

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4918330

Effect of senescence on macrophage polarization and angiogenesis

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4918330

Senescence regulates macrophage activation and angiogenic fate at sites of tissue injury in mice

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4918330

Macular pigment lutein is antiinflammatory in preventing choroidal neovascularization

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4918330

SOCS proteins, cytokine signalling and immune regulation

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4918330

Interleukin-6 receptor-mediated activation of signal transducer and activator of transcription-3 (STAT3) promotes choroidal neovascularization

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4918330

Macrophages inhibit neovascularization in a murine model of age-related macular degeneration

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4918330

Adenosine augments IL-10 production by macrophages through an A2B receptor-mediated posttranscriptional mechanism

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4918330

A common haplotype in the complement regulatory gene factor H (HF1/CFH) predisposes individuals to age-related macular degeneration

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4918330

Macrophage depletion diminishes lesion size and severity in experimental choroidal neovascularization

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4918330

Macrophage depletion inhibits experimental choroidal neovascularization

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4918330

The orphan receptor CRF2-4 is an essential subunit of the interleukin 10 receptor

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4918330

An assay for macrophage-mediated regulation of endothelial cell proliferation

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4918330

Stat3 activation is responsible for IL-6-dependent T cell proliferation through preventing apoptosis: generation and characterization of T cell-specific Stat3-deficient mice.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4918330

Deletion of the SOCS3 gene in liver parenchymal cells promotes hepatitis-induced hepatocarcinogenesis.

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4918330

Loss of SOCS3 in the liver promotes fibrosis by enhancing STAT3-mediated TGF-beta1 production.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4918330

IL-6 induces an anti-inflammatory response in the absence of SOCS3 in macrophages

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4918330

IL-10 expression profiling in human monocytes.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4918330

A simple polymerase chain reaction assay for genotyping the retinal degeneration mutation (Pdeb(rd1)) in FVB/N-derived transgenic mice.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4918330

Conditional gene targeting in macrophages and granulocytes using LysMcre mice.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4918330

Enhanced Th1 activity and development of chronic enterocolitis in mice devoid of Stat3 in macrophages and neutrophils.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4918330

Macrophage Activation and Polarization: Nomenclature and Experimental Guidelines

4 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNCOMMS8847

Age-related macular degeneration

21 January 2018

1 reference

12 December 2020

IKKβ Is Required for Peripheral B Cell Survival and Proliferation

1 reference

12 December 2020

Smoking mice: a potential model for studying accumulation of drusen-like material on Bruch's membrane

1 reference

12 December 2020

Anti-inflammatory M2, but not pro-inflammatory M1 macrophages promote angiogenesis in vivo

1 reference

12 December 2020

The potential angiogenic role of macrophages in the formation of choroidal neovascular membranes

1 reference

12 December 2020

Identifiers

DOI

10.1038/NCOMMS8847

1 reference

Dimensions Publication ID

17 August 2017

0 references

0 references

1 reference

17 August 2017

PubMed publication ID

26260587

1 reference