Plasma sphingolipids are biomarkers of metabolic syndrome in non-human primates maintained on a Western-style diet (Q37033895)

17 August 2017

Plasma sphingolipids are biomarkers of metabolic syndrome in non-human primates maintained on a Western-style diet (English)

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17 August 2017

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J T Brozinick

1

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17 August 2017

E Hawkins

2

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17 August 2017

H Hoang Bui

3

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17 August 2017

M-S Kuo

4

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17 August 2017

B Tan

5

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17 August 2017

P Kievit

6

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17 August 2017

K Grove

7

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17 August 2017

language of work or name

English

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publication date

4 December 2012

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International Journal of Obesity

17 August 2017

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17 August 2017

37

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17 August 2017

1064-1070

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17 August 2017

8

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https://scigraph.springernature.com/pub.10.1038/ijo.2012.191

17 August 2017

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Dynamic modification of sphingomyelin in lipid microdomains controls development of obesity, fatty liver, and type 2 diabetes

29 September 2017

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Comparative plasma lipidome between human and cynomolgus monkey: are plasma polar lipids good biomarkers for diabetic monkeys?

29 September 2017

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Gastric bypass surgery reduces plasma ceramide subspecies and improves insulin sensitivity in severely obese patients

29 September 2017

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Sphingolipids: agents provocateurs in the pathogenesis of insulin resistance

29 September 2017

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Maternal high fat diet is associated with decreased plasma n-3 fatty acids and fetal hepatic apoptosis in nonhuman primates

29 September 2017

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29 September 2017

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Deoxysphingoid bases as plasma markers in diabetes mellitus

29 September 2017

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Exosomes/microvesicles as a mechanism of cell-to-cell communication

29 September 2017

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Mammalian ceramide synthases

29 September 2017

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29 September 2017

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Orm1 and Orm2 are conserved endoplasmic reticulum membrane proteins regulating lipid homeostasis and protein quality control

29 September 2017

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Ceramide-rich platforms in transmembrane signaling

29 September 2017

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Hereditary sensory neuropathy type 1 is caused by the accumulation of two neurotoxic sphingolipids

29 September 2017

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Lipid rafts as a membrane-organizing principle

29 September 2017

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Overexpression of the wild-type SPT1 subunit lowers desoxysphingolipid levels and rescues the phenotype of HSAN1

29 September 2017

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Lipid rafts as functional heterogeneity in cell membranes

29 September 2017

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The SPTLC3 subunit of serine palmitoyltransferase generates short chain sphingoid bases

29 September 2017

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Liver-specific deficiency of serine palmitoyltransferase subunit 2 decreases plasma sphingomyelin and increases apolipoprotein E levels

29 September 2017

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Central role of ceramide biosynthesis in body weight regulation, energy metabolism, and the metabolic syndrome

29 September 2017

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A branched-chain amino acid-related metabolic signature that differentiates obese and lean humans and contributes to insulin resistance

29 September 2017

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Maternal high-fat diet triggers lipotoxicity in the fetal livers of nonhuman primates

29 September 2017

1 reference

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Plasma ceramides are elevated in obese subjects with type 2 diabetes and correlate with the severity of insulin resistance

29 September 2017

1 reference

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Modulating serine palmitoyl transferase (SPT) expression and activity unveils a crucial role in lipid-induced insulin resistance in rat skeletal muscle cells

29 September 2017

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Effects of ceramide and other simple sphingolipids on membrane lateral structure

29 September 2017

1 reference

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Ceramide-enriched membrane domains--structure and function

29 September 2017

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Ceramide triggers budding of exosome vesicles into multivesicular endosomes

29 September 2017

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Dissociation of the insulin receptor and caveolin-1 complex by ganglioside GM3 in the state of insulin resistance

29 September 2017

1 reference

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Inhibition of ceramide synthesis ameliorates glucocorticoid-, saturated-fat-, and obesity-induced insulin resistance

29 September 2017

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Is the mammalian serine palmitoyltransferase a high-molecular-mass complex?

29 September 2017

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Ceramide recruits and activates protein kinase C zeta (PKC zeta) within structured membrane microdomains

29 September 2017

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Cloning and initial characterization of a new subunit for mammalian serine-palmitoyltransferase

29 September 2017

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Insulin resistance as a membrane microdomain disorder

29 September 2017

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Exosomes: a common pathway for a specialized function

29 September 2017

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A role for sphingolipids in producing the common features of type 2 diabetes, metabolic syndrome X, and Cushing's syndrome

29 September 2017

1 reference

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Regulation of insulin action by ceramide: dual mechanisms linking ceramide accumulation to the inhibition of Akt/protein kinase B.

29 September 2017

1 reference

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Ceramide synthesis and metabolism as a target for cancer therapy.

29 September 2017

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Minireview: weapons of lean body mass destruction: the role of ectopic lipids in the metabolic syndrome

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3718866

Serine palmitoyltransferase, a key enzyme of sphingolipid metabolism

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3718866

Enhanced insulin sensitivity in mice lacking ganglioside GM3.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3718866

Hereditary sensory neuropathy type 1 mutations confer dominant negative effects on serine palmitoyltransferase, critical for sphingolipid synthesis.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3718866

Ceramide: second messenger or modulator of membrane structure and dynamics?

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3718866

Ganglioside GM3 participates in the pathological conditions of insulin resistance

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3718866

Lipoapoptosis in beta-cells of obese prediabetic fa/fa rats. Role of serine palmitoyltransferase overexpression

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3718866

Targeting of PKCzeta and PKB to caveolin-enriched microdomains represents a crucial step underpinning the disruption in PKB-directed signalling by ceramide

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3718866

Link between plasma ceramides, inflammation and insulin resistance: association with serum IL-6 concentration in patients with coronary heart disease

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3718866

Increased hepatic expression of ganglioside-specific sialidase, NEU3, improves insulin sensitivity and glucose tolerance in mice.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3718866

Naloxone, but not valsartan, preserves responses to hypoglycemia after antecedent hypoglycemia: role of metabolic reprogramming in counterregulatory failure.

4 September 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2012.191

C-Myc is a Nrf2-interacting protein that negatively regulates phase II genes through their electrophile responsive elements

21 January 2018

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https://api.crossref.org/works/10.1038%2FIJO.2012.191

Effect of ceramide structure on membrane biophysical properties: The role of acyl chain length and unsaturation

21 January 2018

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https://api.crossref.org/works/10.1038%2FIJO.2012.191

Inhibition of atherosclerosis by the serine palmitoyl transferase inhibitor myriocin is associated with reduced plasma glycosphingolipid concentration

21 January 2018

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PubMed

https://pubmed.ncbi.nlm.nih.gov/23207405

12 December 2020

inferred from PubMed ID database lookup

Plasma deoxysphingolipids: a novel class of biomarkers for the metabolic syndrome?

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23207405

12 December 2020

inferred from PubMed ID database lookup

Circulating levels of ganglioside GM3 in metabolic syndrome: A pilot study

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23207405

12 December 2020

inferred from PubMed ID database lookup

Investigation and treatment of type 2 diabetes in nonhuman primates

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2012.191

7 January 2021

inferred from DOI database lookup

Identifiers

DOI

10.1038/IJO.2012.191

1 reference

17 August 2017

1 reference

17 August 2017

1 reference