The tumor-suppressive and potential therapeutic functions of miR-34a in epithelial carcinomas. (Q37041036)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26652031%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

title

The tumor-suppressive and potential therapeutic functions of miR-34a in epithelial carcinomas (English)

1 reference

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2 March 2020

3

1 reference

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2 March 2020

author name string

Brian D Adams

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26652031%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

Christine Parsons

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26652031%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

language of work or name

English

0 references

publication date

11 December 2015

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26652031%20AND%20SRC:MED&resulttype=core&format=json

Expert Opinion on Therapeutic Targets

2 March 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26652031%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

volume

20

1 reference

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2 March 2020

issue

6

1 reference

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2 March 2020

page(s)

737-753

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26652031%20AND%20SRC:MED&resulttype=core&format=json

Combinatorial Action of MicroRNAs let-7 and miR-34 Effectively Synergizes with Erlotinib to Suppress Non-small Cell Lung Cancer Cell Proliferation.

2 March 2020

cites work

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MicroRNA-34a regulates cardiac fibrosis after myocardial infarction by targeting Smad4

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Neoadjuvant Chemotherapy in Breast Cancer Patients Induces miR-34a and miR-122 Expression

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29 September 2017

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miR-34a is an intracellular and exosomal predictive biomarker for response to docetaxel with clinical relevance to prostate cancer progression

29 September 2017

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29 September 2017

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MicroRNA-34a overcomes HGF-mediated gefitinib resistance in EGFR mutant lung cancer cells partly by targeting MET.

29 September 2017

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Two miRNA clusters, miR-34b/c and miR-449, are essential for normal brain development, motile ciliogenesis, and spermatogenesis

29 September 2017

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29 September 2017

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miR-34/449 miRNAs are required for motile ciliogenesis by repressing cp110.

29 September 2017

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Cell-SELEX-based selection of aptamers that recognize distinct targets on metastatic colorectal cancer cells.

29 September 2017

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IL-6R/STAT3/miR-34a feedback loop promotes EMT-mediated colorectal cancer invasion and metastasis

29 September 2017

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The microRNA miR-34a inhibits non-small cell lung cancer (NSCLC) growth and the CD44hi stem-like NSCLC cells

29 September 2017

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Hyaluronic acid-chitosan nanoparticles for co-delivery of MiR-34a and doxorubicin in therapy against triple negative breast cancer

29 September 2017

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In-depth analysis shows synergy between erlotinib and miR-34a

29 September 2017

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Extracellular disposal of tumor-suppressor miRs-145 and -34a via microvesicles and 5-FU resistance of human colon cancer cells

29 September 2017

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Dysregulation of microRNA-34a expression in colorectal cancer inhibits the phosphorylation of FAK via VEGF.

29 September 2017

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Novel strategies targeting cancer stem cells through phytochemicals and their analogs

29 September 2017

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MicroRNA-34a suppresses cell proliferation by targeting LMTK3 in human breast cancer mcf-7 cell line

29 September 2017

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MicroRNA-34a targets Bcl-2 and sensitizes human hepatocellular carcinoma cells to sorafenib treatment

29 September 2017

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A microRNA miR-34a-regulated bimodal switch targets Notch in colon cancer stem cells.

29 September 2017

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CD95 is part of a let-7/p53/miR-34 regulatory network

29 September 2017

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Targeted expression of miR-34a using the T-VISA system suppresses breast cancer cell growth and invasion

29 September 2017

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MicroRNA-34 suppresses breast cancer invasion and metastasis by directly targeting Fra-1.

29 September 2017

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Expression of miR-34 is lost in colon cancer which can be re-expressed by a novel agent CDF.

29 September 2017

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miRNA-34 prevents cancer initiation and progression in a therapeutically resistant K-ras and p53-induced mouse model of lung adenocarcinoma.

29 September 2017

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Epigenetic regulation of miR-34a expression in alcoholic liver injury.

29 September 2017

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miR-34 - a microRNA replacement therapy is headed to the clinic

29 September 2017

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Significance of CD44 and CD24 as cancer stem cell markers: an enduring ambiguity

29 September 2017

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Circulating miR-34a levels are reduced in colorectal cancer

29 September 2017

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Dysregulation of microRNA-34a expression in head and neck squamous cell carcinoma promotes tumor growth and tumor angiogenesis

29 September 2017

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MiR-34a inhibits proliferation and migration of breast cancer through down-regulation of Bcl-2 and SIRT1.

29 September 2017

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MicroRNA-449 and microRNA-34b/c function redundantly in murine testes by targeting E2F transcription factor-retinoblastoma protein (E2F-pRb) pathway.

29 September 2017

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MicroRNA-34a inhibits migration and invasion of colon cancer cells via targeting to Fra-1.

29 September 2017

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miR-34 and SNAIL form a double-negative feedback loop to regulate epithelial-mesenchymal transitions

29 September 2017

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Identification of the receptor tyrosine kinase AXL in breast cancer as a target for the human miR-34a microRNA

29 September 2017

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Mir-34a is upregulated during liver regeneration in rats and is associated with the suppression of hepatocyte proliferation

29 September 2017

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Identification of human triple-negative breast cancer subtypes and preclinical models for selection of targeted therapies

29 September 2017

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Control of vertebrate multiciliogenesis by miR-449 through direct repression of the Delta/Notch pathway

29 September 2017

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miR-34a and miR-15a/16 are co-regulated in non-small cell lung cancer and control cell cycle progression in a synergistic and Rb-dependent manner

29 September 2017

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Myc-mediated repression of microRNA-34a promotes high-grade transformation of B-cell lymphoma by dysregulation of FoxP1

29 September 2017

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Systemic delivery of tumor suppressor microRNA mimics using a neutral lipid emulsion inhibits lung tumors in mice

29 September 2017

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miR-449 inhibits cell proliferation and is down-regulated in gastric cancer

29 September 2017

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miRNA-34a is associated with docetaxel resistance in human breast cancer cells

29 September 2017

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The microRNA miR-34a inhibits prostate cancer stem cells and metastasis by directly repressing CD44

29 September 2017

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Frequent concomitant inactivation of miR-34a and miR-34b/c by CpG methylation in colorectal, pancreatic, mammary, ovarian, urothelial, and renal cell carcinomas and soft tissue sarcomas

29 September 2017

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Dysregulation of microRNA-34a expression causes drug-resistance to 5-FU in human colon cancer DLD-1 cells

29 September 2017

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Circulating microRNAs, possible indicators of progress of rat hepatocarcinogenesis from early stages

29 September 2017

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C/EBPα regulated microRNA-34a targets E2F3 during granulopoiesis and is down-regulated in AML with CEBPA mutations

29 September 2017

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Development of a lung cancer therapeutic based on the tumor suppressor microRNA-34

29 September 2017

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MicroRNA-34a inhibits cell proliferation by repressing mitogen-activated protein kinase kinase 1 during megakaryocytic differentiation of K562 cells

29 September 2017

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The impact of miR-34a on protein output in hepatocellular carcinoma HepG2 cells

29 September 2017

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miR-449a and miR-449b are direct transcriptional targets of E2F1 and negatively regulate pRb-E2F1 activity through a feedback loop by targeting CDK6 and CDC25A.

29 September 2017

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miR-34a contributes to megakaryocytic differentiation of K562 cells independently of p53.

29 September 2017

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The miR-34 family in cancer and apoptosis

29 September 2017

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The mir-34 microRNA is required for the DNA damage response in vivo in C. elegans and in vitro in human breast cancer cells

29 September 2017

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MicroRNA involvement in the pathogenesis of neuroblastoma: potential for microRNA mediated therapeutics

29 September 2017

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miR-34a, miR-29c and miR-17-5p are downregulated in CLL patients with TP53 abnormalities

29 September 2017

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miR-34a inhibits migration and invasion by down-regulation of c-Met expression in human hepatocellular carcinoma cells

29 September 2017

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Most mammalian mRNAs are conserved targets of microRNAs

29 September 2017

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Down-regulation of the microRNAs miR-34a, miR-127, and miR-200b in rat liver during hepatocarcinogenesis induced by a methyl-deficient diet

29 September 2017

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Effects of miR-34a on cell growth and chemoresistance in prostate cancer PC3 cells

29 September 2017

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29 September 2017

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miR-34a repression of SIRT1 regulates apoptosis

29 September 2017

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Inactivation of miR-34a by aberrant CpG methylation in multiple types of cancer

29 September 2017

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Alterations in microRNA expression contribute to fatty acid-induced pancreatic beta-cell dysfunction

29 September 2017

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microRNAs join the p53 network--another piece in the tumour-suppression puzzle

29 September 2017

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Tumor-suppressive miR-34a induces senescence-like growth arrest through modulation of the E2F pathway in human colon cancer cells

29 September 2017

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p53-mediated activation of miRNA34 candidate tumor-suppressor genes.

29 September 2017

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Transactivation of miR-34a by p53 broadly influences gene expression and promotes apoptosis

29 September 2017

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Transcriptional activation of miR-34a contributes to p53-mediated apoptosis

29 September 2017

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CD44+/CD24- breast cancer cells exhibit enhanced invasive properties: an early step necessary for metastasis

29 September 2017

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Acquired resistance of lung adenocarcinomas to gefitinib or erlotinib is associated with a second mutation in the EGFR kinase domain

29 September 2017

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MicroRNAs: genomics, biogenesis, mechanism, and function

29 September 2017

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29 September 2017

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miRNPs: a novel class of ribonucleoproteins containing numerous microRNAs

21 January 2018

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Regulation of the c-met proto-oncogene promoter by p53.

29 September 2017

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Intact p53-dependent responses in miR-34-deficient mice.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4922263

Targeting of miR34a-NOTCH1 axis reduced breast cancer stemness and chemoresistance.

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4922263

Deregulated serum concentrations of circulating cell-free microRNAs miR-17, miR-34a, miR-155, and miR-373 in human breast cancer development and progression.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4922263

MicroRNA-34a regulates cardiac ageing and function.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4922263

Downregulation of miR-34a in breast tumors is not associated with either p53 mutations or promoter hypermethylation while it correlates with metastasis.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4922263

Detection of miR-34a promoter methylation in combination with elevated expression of c-Met and β-catenin predicts distant metastasis of colon cancer

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4922263

The quantitative analysis by stem-loop real-time PCR revealed the microRNA-34a, microRNA-155 and microRNA-200c overexpression in human colorectal cancer.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4922263

MiR-34a attenuates paclitaxel-resistance of hormone-refractory prostate cancer PC3 cells through direct and indirect mechanisms

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4922263

miR-34a as a prognostic marker of relapse in surgically resected non-small-cell lung cancer.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4922263

Differential regulation of microRNAs by p53 revealed by massively parallel sequencing: miR-34a is a p53 target that induces apoptosis and G1-arrest.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4922263

4 September 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2016.1114102

Interdependent regulation of p53 and miR-34a in chronic lymphocytic leukemia

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1517%2F14728222.2016.1114102

Erratum: Control of vertebrate multiciliogenesis by miR-449 through direct repression of the Delta/Notch pathway

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1517%2F14728222.2016.1114102

MiR-34a inhibits lipopolysaccharide-induced inflammatory response through targeting Notch1 in murine macrophages

21 January 2018

1 reference

12 December 2020

17p13/TP53 deletion in B-CLL patients is associated with microRNA-34a downregulation

1 reference

12 December 2020

MicroRNA-34a modulates chemosensitivity of breast cancer cells to adriamycin by targeting Notch1

1 reference

12 December 2020

Breast cancer. Introduction.

1 reference

12 December 2020

First microRNA mimic enters clinic

1 reference

12 December 2020

DNA hypermethylation of microRNA-34b/c has prognostic value for stage Ⅰ non-small cell lung cancer

1 reference

12 December 2020

Interdependent regulation of p53 and miR-34a in chronic lymphocytic leukemia

1 reference

12 December 2020

10.1517/14728222.2016.1114102

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26652031%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26652031%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26652031%20AND%20SRC:MED&resulttype=core&format=json