Combining FoxP3 and Helios with GARP/LAP markers can identify expanded Treg subsets in cancer patients. (Q37046528)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26885615%20AND%20SRC:MED&resulttype=core&format=json

8 March 2020

title

Combining FoxP3 and Helios with GARP/LAP markers can identify expanded Treg subsets in cancer patients (English)

1 reference

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8 March 2020

2

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8 March 2020

Yazan Khaled

3

1 reference

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8 March 2020

Eyad Elkord

5

1 reference

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8 March 2020

author name string

May Abd Al Samid

1

1 reference

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8 March 2020

Basil J Ammori

4

1 reference

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8 March 2020

language of work or name

English

0 references

publication date

1 March 2016

1 reference

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8 March 2020

1 reference

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8 March 2020

volume

7

1 reference

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8 March 2020

issue

12

1 reference

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8 March 2020

page(s)

14083-14094

1 reference

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Helios Controls a Limited Subset of Regulatory T Cell Functions

8 March 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4924699

Helios, and not FoxP3, is the marker of activated Tregs expressing GARP/LAP.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4924699

Phenotypic Complexity of the Human Regulatory T Cell Compartment Revealed by Mass Cytometry

29 September 2017

1 reference

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Monitoring regulatory T cells in clinical samples: consensus on an essential marker set and gating strategy for regulatory T cell analysis by flow cytometry

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4924699

Helios Enhances Treg Cell Function in Cooperation With FoxP3.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4924699

CD4⁺ T cells expressing latency-associated peptide and Foxp3 are an activated subgroup of regulatory T cells enriched in patients with colorectal cancer

29 September 2017

1 reference

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Organ-specific and memory treg cells: specificity, development, function, and maintenance

29 September 2017

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Phenotypic alterations, clinical impact and therapeutic potential of regulatory T cells in cancer

29 September 2017

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Regulatory T cells as immunotherapy

29 September 2017

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Homeostatic control of regulatory T cell diversity.

29 September 2017

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Regulatory T cells in cancer immunotherapy

29 September 2017

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Effects of adjuvant chemoradiotherapy on the frequency and function of regulatory T cells in patients with head and neck cancer

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4924699

Highly prevalent colorectal cancer-infiltrating LAP⁺ Foxp3⁻ T cells exhibit more potent immunosuppressive activity than Foxp3⁺ regulatory T cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4924699

Higher frequencies of GARP(+)CTLA-4(+)Foxp3(+) T regulatory cells and myeloid-derived suppressor cells in hepatocellular carcinoma patients are associated with impaired T-cell functionality

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4924699

Transient Foxp3(+) regulatory T-cell depletion enhances therapeutic anticancer vaccination targeting the immune-stimulatory properties of NKT cells

29 September 2017

1 reference

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Phenotypic and functional properties of Helios+ regulatory T cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4924699

Functionally distinct subsets of human FOXP3+ Treg cells that phenotypically mirror effector Th cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4924699

Helios expression is a marker of T cell activation and proliferation.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4924699

T regulatory cells in cancer: recent advances and therapeutic potential

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4924699

Cutting edge: human latency-associated peptide+ T cells: a novel regulatory T cell subset

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4924699

FOXP3 and GARP (LRRC32): the master and its minion

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4924699

GARP (LRRC32) is essential for the surface expression of latent TGF-beta on platelets and activated FOXP3+ regulatory T cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4924699

Selective expression of latency-associated peptide (LAP) and IL-1 receptor type I/II (CD121a/CD121b) on activated human FOXP3+ regulatory T cells allows for their purification from expansion cultures

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4924699

Regulatory T cells and immune tolerance

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4924699

Latent transforming growth factor-beta (TGF-beta) binding proteins: orchestrators of TGF-beta availability

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4924699

Monoclonal antibodies against GARP/TGF-β1 complexes inhibit the immunosuppressive activity of human regulatory T cells in vivo.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4924699

Foxp3+ Helios+ regulatory T cells are expanded in active systemic lupus erythematosus

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4924699

CCR 20th Anniversary Commentary: From Regulatory T Cells to Checkpoint Monoclonal Antibodies--Immuno-oncology Advances Clinical Cancer Research.

27 June 2018

1 reference

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Impaired Th1 immunity in ovarian cancer patients is mediated by TNFR2+ Tregs within the tumor microenvironment

4 September 2018

1 reference

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Developmental plasticity of murine and human Foxp3(+) regulatory T cells

4 September 2018

1 reference

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Multiparameter single-cell profiling of human CD4+FOXP3+ regulatory T-cell populations in homeostatic conditions and during graft-versus-host disease.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4924699

LAP+CD4+ T cells are suppressors accumulated in the tumor sites and associated with the progression of colorectal cancer.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4924699

Prevalence of FOXP3+ regulatory T cells increases during the progression of pancreatic ductal adenocarcinoma and its premalignant lesions.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4924699

Identification of human regulatory T cells in the setting of T-cell activation and anti-CTLA-4 immunotherapy on the basis of expression of latency-associated peptide

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4924699

Helios expression in FoxP3(+) T regulatory cells

20 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26885615

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Expanded subpopulation of FoxP3+ T regulatory cells in renal cell carcinoma co-express Helios, indicating they could be derived from natural but not induced Tregs

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26885615

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Activated tumor-infiltrating CD4+ regulatory T cells restrain antitumor immunity in patients with primary or metastatic liver cancer

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26885615

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.18632/ONCOTARGET.7334

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26885615%20AND%20SRC:MED&resulttype=core&format=json

8 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26885615%20AND%20SRC:MED&resulttype=core&format=json

8 March 2020

PubMed publication ID

26885615

1 reference