Antimicrobial resistance: resistance to antifungal agents: mechanisms and clinical impact (Q37048679)

17 August 2017

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title

Antimicrobial resistance: resistance to antifungal agents: mechanisms and clinical impact (English)

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17 August 2017

antimicrobial resistance

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2

John R Perfect

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17 August 2017

Zeina A Kanafani

1

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PubMed ID

18171227

17 August 2017

language of work or name

English

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publication date

1 January 2008

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Clinical Infectious Diseases

17 August 2017

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17 August 2017

46

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17 August 2017

1

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17 August 2017

120-128

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The changing epidemiology of invasive fungal infections: new threats

17 August 2017

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Susceptibility of environmental versus clinical strains of pathogenic Aspergillus.

21 January 2018

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Molecular studies reveal frequent misidentification of Aspergillus fumigatus by morphotyping

21 January 2018

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Fatal Blastoschizomyces capitatus sepsis in a neutropenic patient with acute myeloid leukemia: first documented case from Greece

21 January 2018

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In vitro susceptibilities of zygomycetes to conventional and new antifungals

21 January 2018

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Biofilm formation by the emerging fungal pathogen Trichosporon asahii: development, architecture, and antifungal resistance

21 January 2018

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Optimal testing conditions for determining MICs and minimum fungicidal concentrations of new and established antifungal agents for uncommon molds: NCCLS collaborative study

21 January 2018

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In vitro susceptibility testing of Geotrichum capitatum: comparison of the E-test, disk diffusion, and Sensititre colorimetric methods with the NCCLS M27-A2 broth microdilution reference method

21 January 2018

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In Vitro Activities of Three Licensed Antifungal Agents against Spanish Clinical Isolates of Aspergillus spp

21 January 2018

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In-vitro activity of voriconazole, itraconazole and amphotericin B against filamentous fungi

21 January 2018

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In vitro activities of new and conventional antifungal agents against clinical Scedosporium isolates

21 January 2018

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Aspergillus ustus infections among transplant recipients

21 January 2018

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In vitro activity of two echinocandin derivatives, LY303366 and MK-0991 (L-743,792), against clinical isolates of Aspergillus, Fusarium, Rhizopus, and other filamentous fungi

21 January 2018

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Antifungal activities of posaconazole, ravuconazole, and voriconazole compared to those of itraconazole and amphotericin B against 239 clinical isolates of Aspergillus spp. and other filamentous fungi: report from SENTRY Antimicrobial Surveillance P

21 January 2018

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Susceptibility patterns and molecular identification of Trichosporon species

21 January 2018

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Progressive cutaneous hyalohyphomycosis due to Paecilomyces lilacinus: rapid response to treatment with caspofungin and itraconazole

21 January 2018

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In vitro susceptibility of 15 strains of zygomycetes to nine antifungal agents as determined by the NCCLS M38-A microdilution method

21 January 2018

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Development of secondary resistance to fluconazole in Cryptococcus neoformans isolated from a patient with AIDS.

21 January 2018

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Contribution of mutations in the cytochrome P450 14alpha-demethylase (Erg11p, Cyp51p) to azole resistance in Candida albicans.

21 January 2018

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Comparison of the EUCAST-AFST broth dilution method with the CLSI reference broth dilution method (M38-A) for susceptibility testing of posaconazole and voriconazole against Aspergillus spp.

21 January 2018

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International and multicenter comparison of EUCAST and CLSI M27-A2 broth microdilution methods for testing susceptibilities of Candida spp. to fluconazole, itraconazole, posaconazole, and voriconazole

21 January 2018

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Has antifungal susceptibility testing come of age?

21 January 2018

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Morphological effects of lipopeptides against Aspergillus fumigatus correlate with activities against (1,3)-beta-D-glucan synthase

21 January 2018

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Three-dimensional models of wild-type and mutated forms of cytochrome P450 14alpha-sterol demethylases from Aspergillus fumigatus and Candida albicans provide insights into posaconazole binding.

21 January 2018

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Head-to-head comparison of the activities of currently available antifungal agents against 3,378 Spanish clinical isolates of yeasts and filamentous fungi.

21 January 2018

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Voriconazole against fluconazole-susceptible and resistant candida isolates: in-vitro efficacy compared with that of itraconazole and ketoconazole.

21 January 2018

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In vitro activities of voriconazole, posaconazole, and fluconazole against 4,169 clinical isolates of Candida spp. and Cryptococcus neoformans collected during 2001 and 2002 in the ARTEMIS global antifungal surveillance program

21 January 2018

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Cross-resistance between fluconazole and ravuconazole and the use of fluconazole as a surrogate marker to predict susceptibility and resistance to ravuconazole among 12,796 clinical isolates of Candida spp

21 January 2018

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Use of fluconazole as a surrogate marker to predict susceptibility and resistance to voriconazole among 13,338 clinical isolates of Candida spp. Tested by clinical and laboratory standards institute-recommended broth microdilution methods

21 January 2018

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Does long-term itraconazole prophylaxis result in in vitro azole resistance in mucosal Candida albicans isolates from persons with advanced human immunodeficiency virus infection? The National Institute of Allergy and Infectious Diseases Mycoses stu

21 January 2018

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High prevalence of antifungal resistance in Candida spp. from patients with AIDS.

21 January 2018

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Phenotypic and genotypic evaluation of fluconazole resistance in vaginal Candida strains isolated from HIV-infected women from Brazil

21 January 2018

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Resistance of Candida species to antifungal agents: molecular mechanisms and clinical consequences

21 January 2018

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Twelve years of fluconazole in clinical practice: global trends in species distribution and fluconazole susceptibility of bloodstream isolates of Candida.

21 January 2018

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Results from the ARTEMIS DISK Global Antifungal Surveillance Study: a 6.5-year analysis of susceptibilities of Candida and other yeast species to fluconazole and voriconazole by standardized disk diffusion testing.

21 January 2018

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Interpretive breakpoints for fluconazole and Candida revisited: a blueprint for the future of antifungal susceptibility testing

21 January 2018

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Incidence of bloodstream infections due to Candida species and in vitro susceptibilities of isolates collected from 1998 to 2000 in a population-based active surveillance program

21 January 2018

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Epidemiology of invasive candidiasis: a persistent public health problem

21 January 2018

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Fluconazole susceptibilities of Candida species and distribution of species recovered from blood cultures over a 5-year period

21 January 2018

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Candidemia before and during the fluconazole era: prevalence, type of species and approach to treatment in a tertiary care community hospital

21 January 2018

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Effect of fluconazole consumption on long-term trends in candidal ecology

21 January 2018

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Prior antimicrobial therapy and risk for hospital-acquired Candida glabrata and Candida krusei fungemia: a case-case-control study

21 January 2018

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Candida glabrata fungemia: experience in a tertiary care center

21 January 2018

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Cloning of Candida albicans genes conferring resistance to azole antifungal agents: characterization of CDR2, a new multidrug ABC transporter gene.

21 January 2018

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Mechanisms of resistance to azole antifungal agents in Candida albicans isolates from AIDS patients involve specific multidrug transporters

21 January 2018

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Amino acid substitutions in the cytochrome P-450 lanosterol 14alpha-demethylase (CYP51A1) from azole-resistant Candida albicans clinical isolates contribute to resistance to azole antifungal agents

21 January 2018

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Increased expression of a novel Aspergillus fumigatus ABC transporter gene, atrF, in the presence of itraconazole in an itraconazole resistant clinical isolate

21 January 2018

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Mutations in Aspergillus fumigatus resulting in reduced susceptibility to posaconazole appear to be restricted to a single amino acid in the cytochrome P450 14alpha-demethylase

21 January 2018

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Substitutions at methionine 220 in the 14alpha-sterol demethylase (Cyp51A) of Aspergillus fumigatus are responsible for resistance in vitro to azole antifungal drugs

21 January 2018

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A new Aspergillus fumigatus resistance mechanism conferring in vitro cross-resistance to azole antifungals involves a combination of cyp51A alterations.

21 January 2018

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The European Confederation of Medical Mycology (ECMM) survey of candidaemia in Italy: in vitro susceptibility of 375 Candida albicans isolates and biofilm production

21 January 2018

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Geographic variation in the susceptibilities of invasive isolates of Candida glabrata to seven systemically active antifungal agents: a global assessment from the ARTEMIS Antifungal Surveillance Program conducted in 2001 and 2002.

21 January 2018

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Strain delineation and antifungal susceptibilities of epidemiologically related and unrelated isolates of Candida lusitaniae.

21 January 2018

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Detection of amphotericin B-resistant Candida isolates in a broth-based system

21 January 2018

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Comparison of Etest and National Committee for Clinical Laboratory Standards broth macrodilution method for antifungal susceptibility testing: enhanced ability to detect amphotericin B-resistant Candida isolates

21 January 2018

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In vitro activities of posaconazole, fluconazole, itraconazole, voriconazole, and amphotericin B against a large collection of clinically important molds and yeasts

21 January 2018

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International surveillance of Candida spp. and Aspergillus spp.: report from the SENTRY Antimicrobial Surveillance Program (2003).

21 January 2018

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Aspergillus lentulus sp. nov., a new sibling species of A. fumigatus

21 January 2018

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Incidence of polyene-resistant yeasts recovered from clinical specimens

21 January 2018

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Comparison of caspofungin and amphotericin B for invasive candidiasis

21 January 2018

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Development of candidemia on caspofungin therapy: a case report.

21 January 2018

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Interlaboratory comparison of results of susceptibility testing with caspofungin against Candida and Aspergillus species

21 January 2018

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Assessing resistance to the echinocandin antifungal drug caspofungin in Candida albicans by profiling mutations in FKS1

21 January 2018

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The effect of the echinocandin analogue caspofungin on cell wall glucan synthesis by Cryptococcus neoformans

21 January 2018

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Paradoxical effect of caspofungin: reduced activity against Candida albicans at high drug concentrations

21 January 2018

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Escape of Candida from caspofungin inhibition at concentrations above the MIC (paradoxical effect) accomplished by increased cell wall chitin; evidence for beta-1,6-glucan synthesis inhibition by caspofungin

21 January 2018

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Assessment of the paradoxical effect of caspofungin in therapy of candidiasis

21 January 2018

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Emergence of a Candida krusei isolate with reduced susceptibility to caspofungin during therapy

21 January 2018

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Caspofungin resistance in Candida albicans: correlating clinical outcome with laboratory susceptibility testing of three isogenic isolates serially obtained from a patient with progressive Candida esophagitis

21 January 2018

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Progressive loss of echinocandin activity following prolonged use for treatment of Candida albicans oesophagitis

21 January 2018

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Multiechinocandin- and multiazole-resistant Candida parapsilosis isolates serially obtained during therapy for prosthetic valve endocarditis

21 January 2018

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Trends in antifungal drug susceptibility of Cryptococcus neoformans isolates in the United States: 1992 to 1994 and 1996 to 1998.

21 January 2018

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Flucytosine monotherapy for cryptococcosis.

21 January 2018

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Voriconazole versus amphotericin B for primary therapy of invasive aspergillosis

21 January 2018

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Treatment of cryptococcal meningitis associated with the acquired immunodeficiency syndrome. National Institute of Allergy and Infectious Diseases Mycoses Study Group and AIDS Clinical Trials Group

21 January 2018

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Immune reconstitution syndrome associated with opportunistic mycoses

21 January 2018

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Recombinant interferon- gamma 1b as adjunctive therapy for AIDS-related acute cryptococcal meningitis.

21 January 2018

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Delaying the empiric treatment of candida bloodstream infection until positive blood culture results are obtained: a potential risk factor for hospital mortality

21 January 2018

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Invasive aspergillosis following hematopoietic cell transplantation: outcomes and prognostic factors associated with mortality

21 January 2018

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Same-sex mating and the origin of the Vancouver Island Cryptococcus gattii outbreak

21 January 2018

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Cryptococcus neoformans infections at Vancouver Hospital and Health Sciences Centre (1997-2002): epidemiology, microbiology and histopathology

21 January 2018

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International, open-label, noncomparative, clinical trial of micafungin alone and in combination for treatment of newly diagnosed and refractory candidemia.

21 January 2018

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Pharmacokinetics and pharmacodynamics of antifungals

21 January 2018

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Drug interactions during therapy with three major groups of antimicrobial agents

21 January 2018

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Efficacy and safety of voriconazole in the treatment of acute invasive aspergillosis

21 January 2018

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Voriconazole therapeutic drug monitoring.

21 January 2018

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Monitoring plasma voriconazole levels may be necessary to avoid subtherapeutic levels in hematopoietic stem cell transplant recipients

21 January 2018

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Treatment of invasive aspergillosis with posaconazole in patients who are refractory to or intolerant of conventional therapy: an externally controlled trial

21 January 2018

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Comparison of fluconazole pharmacokinetics in serum, aqueous humor, vitreous humor, and cerebrospinal fluid following a single dose and at steady state.

21 January 2018

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Voriconazole concentrations in the cerebrospinal fluid and brain tissue of guinea pigs and immunocompromised patients

21 January 2018

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Antifungal susceptibility of Candida biofilms: unique efficacy of amphotericin B lipid formulations and echinocandins

21 January 2018

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Epidemiology and predictors of mortality in cases of Candida bloodstream infection: results from population-based surveillance, barcelona, Spain, from 2002 to 2003.

21 January 2018

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Management of central venous catheters in patients with cancer and candidemia

21 January 2018

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21 January 2018

Identifiers

DOI

10.1086/524071

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17 August 2017

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PubMed ID

18171227