MerTK inhibition in tumor leukocytes decreases tumor growth and metastasis (Q37052927)

17 August 2017

MerTK inhibition in tumor leukocytes decreases tumor growth and metastasis (English)

1 reference

17 August 2017

Rebecca S Cook

1

1 reference

17 August 2017

Kristen M Jacobsen

2

1 reference

17 August 2017

Anne M Wofford

3

1 reference

17 August 2017

Deborah DeRyckere

4

1 reference

17 August 2017

Jamie Stanford

5

1 reference

17 August 2017

Anne L Prieto

6

1 reference

17 August 2017

Elizabeth Redente

7

1 reference

17 August 2017

Melissa Sandahl

8

1 reference

17 August 2017

Debra M Hunter

9

1 reference

17 August 2017

Karen E Strunk

10

1 reference

17 August 2017

Douglas K Graham

11

1 reference

17 August 2017

H Shelton Earp

12

1 reference

17 August 2017

language of work or name

English

0 references

publication date

8 July 2013

1 reference

Journal of Clinical Investigation

17 August 2017

1 reference

17 August 2017

123

1 reference

17 August 2017

8

1 reference

17 August 2017

3231-3242

1 reference

describes a project that uses

17 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3726162/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

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Cross-phosphorylation, signaling and proliferative functions of the Tyro3 and Axl receptors in Rat2 cells

29 September 2017

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Mer receptor tyrosine kinase promotes invasion and survival in glioblastoma multiforme

29 September 2017

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Origins of the tumor microenvironment: quantitative assessment of adipose-derived and bone marrow-derived stroma

29 September 2017

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Differential macrophage programming in the tumor microenvironment

29 September 2017

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The receptor tyrosine kinase ErbB3 maintains the balance between luminal and basal breast epithelium

29 September 2017

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A microRNA regulon that mediates endothelial recruitment and metastasis by cancer cells

29 September 2017

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Profiling of antibody production against xenograft-released proteins by protein microarrays discovers prostate cancer markers

29 September 2017

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Leukocyte complexity predicts breast cancer survival and functionally regulates response to chemotherapy

29 September 2017

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Integrated molecular profiles of invasive breast tumors and ductal carcinoma in situ (DCIS) reveal differential vascular and interleukin signaling

29 September 2017

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Galectin-3 is a new MerTK-specific eat-me signal

29 September 2017

1 reference

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Phosphoproteomic screen identifies potential therapeutic targets in melanoma

29 September 2017

1 reference

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ErbB3 ablation impairs PI3K/Akt-dependent mammary tumorigenesis

29 September 2017

1 reference

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Epithelial cell-directed efferocytosis in the post-partum mammary gland is necessary for tissue homeostasis and future lactation

29 September 2017

1 reference

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Improved prognostic classification of breast cancer defined by antagonistic activation patterns of immune response pathway modules

29 September 2017

1 reference

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TAM receptor signaling and autoimmune disease

29 September 2017

1 reference

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Tubby and tubby-like protein 1 are new MerTK ligands for phagocytosis

29 September 2017

1 reference

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HMGB1 inhibits macrophage activity in efferocytosis through binding to the alphavbeta3-integrin

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3726162

Disrupted Mer receptor tyrosine kinase expression leads to enhanced MZ B-cell responses

29 September 2017

1 reference

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Taking aim at Mer and Axl receptor tyrosine kinases as novel therapeutic targets in solid tumors

29 September 2017

1 reference

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Inhibition of Mer and Axl receptor tyrosine kinases in astrocytoma cells leads to increased apoptosis and improved chemosensitivity

29 September 2017

1 reference

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Macrophage diversity enhances tumor progression and metastasis

29 September 2017

1 reference

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Immunity, Inflammation, and Cancer

29 September 2017

1 reference

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Alternatively activated macrophages and collagen remodeling characterize the postpartum involuting mammary gland across species

29 September 2017

1 reference

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A distinct macrophage population mediates metastatic breast cancer cell extravasation, establishment and growth

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3726162

Trophic macrophages in development and disease

29 September 2017

1 reference

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TAM receptor tyrosine kinases: biologic functions, signaling, and potential therapeutic targeting in human cancer

29 September 2017

1 reference

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Immunobiology of the TAM receptors

29 September 2017

1 reference

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TAM receptors are pleiotropic inhibitors of the innate immune response

29 September 2017

1 reference

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Macrophages and dendritic cells use different Axl/Mertk/Tyro3 receptors in clearance of apoptotic cells

29 September 2017

1 reference

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Tumor signaling to the bone marrow changes the phenotype of monocytes and pulmonary macrophages during urethane-induced primary lung tumorigenesis in A/J mice

29 September 2017

1 reference

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Gas6 and protein S. Vitamin K-dependent ligands for the Axl receptor tyrosine kinase subfamily.

29 September 2017

1 reference

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Ectopic expression of the proto-oncogene Mer in pediatric T-cell acute lymphoblastic leukemia

29 September 2017

1 reference

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Tumour-educated macrophages promote tumour progression and metastasis

29 September 2017

1 reference

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Interleukin-12 and the regulation of innate resistance and adaptive immunity

29 September 2017

1 reference

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Macrophage regulation by Tyro 3 family receptors

29 September 2017

1 reference

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Delayed apoptotic cell clearance and lupus-like autoimmunity in mice lacking the c-mer membrane tyrosine kinase

29 September 2017

1 reference

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Homeostatic regulation of the immune system by receptor tyrosine kinases of the Tyro 3 family

29 September 2017

1 reference

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Phagocytosis and clearance of apoptotic cells is mediated by MER.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3726162

Colony-stimulating factor 1 promotes progression of mammary tumors to malignancy

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3726162

Mutations in MERTK, the human orthologue of the RCS rat retinal dystrophy gene, cause retinitis pigmentosa

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3726162

Tyro-3 family receptors are essential regulators of mammalian spermatogenesis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3726162

Identification of the product of growth arrest-specific gene 6 as a common ligand for Axl, Sky, and Mer receptor tyrosine kinases

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3726162

Cloning and mRNA expression analysis of a novel human protooncogene, c-mer

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3726162

The anticoagulation factor protein S and its relative, Gas6, are ligands for the Tyro 3/Axl family of receptor tyrosine kinases

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3726162

Axl receptor tyrosine kinase stimulated by the vitamin K-dependent protein encoded by growth-arrest-specific gene 6

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3726162

Exposure of phosphatidylserine on the surface of apoptotic lymphocytes triggers specific recognition and removal by macrophages

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3726162

Induction of mammary tumors by expression of polyomavirus middle T oncogene: a transgenic mouse model for metastatic disease

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3726162

Autophosphorylation docking site Tyr-867 in Mer receptor tyrosine kinase allows for dissociation of multiple signaling pathways for phagocytosis of apoptotic cells and down-modulation of lipopolysaccharide-inducible NF-kappaB transcriptional activat

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3726162

A novel receptor tyrosine kinase, Mer, inhibits TNF-alpha production and lipopolysaccharide-induced endotoxic shock.

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3726162

Proinflammatory clearance of apoptotic neutrophils induces an IL-12(low)IL-10(high) regulatory phenotype in macrophages

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3726162

Malignant cells fuel tumor growth by educating infiltrating leukocytes to produce the mitogen Gas6.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3726162

The Mer receptor tyrosine kinase is required for the loss of B cell tolerance in the chronic graft-versus-host disease model of systemic lupus erythematosus

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3726162

Lymphoblastic leukemia/lymphoma in mice overexpressing the Mer (MerTK) receptor tyrosine kinase

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3726162

The mer receptor tyrosine kinase: expression and function suggest a role in innate immunity

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3726162

A Paracrine Loop between Tumor Cells and Macrophages Is Required for Tumor Cell Migration in Mammary Tumors

4 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23867499

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Impaired tumor growth in colony-stimulating factor 1 (CSF-1)-deficient, macrophage-deficient op/op mouse: evidence for a role of CSF-1-dependent macrophages in formation of tumor stroma

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23867499

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1172/JCI67655

1 reference

17 August 2017

1 reference

17 August 2017

PubMed publication ID

23867499

1 reference