Regulation of fatty acid metabolism by mTOR in adult murine hearts occurs independently of changes in PGC-1α (Q37054943)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23624629%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

title

Regulation of fatty acid metabolism by mTOR in adult murine hearts occurs independently of changes in PGC-1α (English)

1 reference

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29 February 2020

0 references

6

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29 February 2020

Don A McClain

8

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29 February 2020

E. Dale Abel

9

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29 February 2020

author name string

Yi Zhu

1

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29 February 2020

Jamie Soto

2

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29 February 2020

Brandon Anderson

3

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29 February 2020

Christian Riehle

4

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29 February 2020

Yi Cheng Zhang

5

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29 February 2020

Deborah Jones

7

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29 February 2020

publication date

26 April 2013

1 reference

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American Journal of Physiology Heart and Circulatory Physiology

29 February 2020

published in

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29 February 2020

volume

305

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29 February 2020

issue

1

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29 February 2020

page(s)

H41-51

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Mechanistic target of rapamycin (Mtor) is essential for murine embryonic heart development and growth

29 February 2020

cites work

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Cardiac PI3K-Akt impairs insulin-stimulated glucose uptake independent of mTORC1 and GLUT4 translocation.

29 September 2017

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Myopathy caused by mammalian target of rapamycin complex 1 (mTORC1) inactivation is not reversed by restoring mitochondrial function

29 September 2017

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Oxidation of hepatic carnitine palmitoyl transferase-I (CPT-I) impairs fatty acid beta-oxidation in rats fed a methionine-choline deficient diet

29 September 2017

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PGC-1β deficiency accelerates the transition to heart failure in pressure overload hypertrophy

29 September 2017

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Regulation of the mTOR Complex 1 Pathway by Nutrients, Growth Factors, and Stress

29 September 2017

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mTOR attenuates the inflammatory response in cardiomyocytes and prevents cardiac dysfunction in pathological hypertrophy

29 September 2017

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MTORC1 regulates cardiac function and myocyte survival through 4E-BP1 inhibition in mice

29 September 2017

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TOR complex 2: a signaling pathway of its own.

29 September 2017

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mTOR signaling at a glance

29 September 2017

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Rapamycin fed late in life extends lifespan in genetically heterogeneous mice

29 September 2017

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The Randle cycle revisited: a new head for an old hat.

29 September 2017

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mTOR complex 2 in adipose tissue negatively controls whole-body growth

29 September 2017

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ULK1.ATG13.FIP200 complex mediates mTOR signaling and is essential for autophagy

29 September 2017

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ULK-Atg13-FIP200 complexes mediate mTOR signaling to the autophagy machinery

29 September 2017

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Skeletal muscle-specific ablation of raptor, but not of rictor, causes metabolic changes and results in muscle dystrophy

29 September 2017

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The Rag GTPases bind raptor and mediate amino acid signaling to mTORC1

29 September 2017

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mTOR controls mitochondrial oxidative function through a YY1-PGC-1alpha transcriptional complex

29 September 2017

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Post-translational modifications of rat liver mitochondrial outer membrane proteins identified by mass spectrometry

29 September 2017

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Reduced mitochondrial oxidative capacity and increased mitochondrial uncoupling impair myocardial energetics in obesity

29 September 2017

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Reduced cardiac efficiency and altered substrate metabolism precedes the onset of hyperglycemia and contractile dysfunction in two mouse models of insulin resistance and obesity.

29 September 2017

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Disruption of the mouse mTOR gene leads to early postimplantation lethality and prohibits embryonic stem cell development

29 September 2017

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mTOR is essential for growth and proliferation in early mouse embryos and embryonic stem cells

29 September 2017

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Overexpression of glutamine:fructose-6-phosphate amidotransferase in transgenic mice leads to insulin resistance

29 September 2017

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Metabolic fuel selection: general integration at the whole-body level

29 September 2017

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Avoidance of transient cardiomyopathy in cardiomyocyte-targeted tamoxifen-induced MerCreMer gene deletion models

29 September 2017

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Cardiac raptor ablation impairs adaptive hypertrophy, alters metabolic gene expression, and causes heart failure in mice.

27 June 2018

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Cytoplasmic and nuclear distribution of the protein complexes mTORC1 and mTORC2: rapamycin triggers dephosphorylation and delocalization of the mTORC2 components rictor and sin1.

4 September 2018

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A role for the transcriptional coactivator PGC-1alpha in muscle refueling

4 September 2018

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Mitochondrial energetics in the heart in obesity-related diabetes: direct evidence for increased uncoupled respiration and activation of uncoupling proteins.

4 September 2018

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Impaired cardiac efficiency and increased fatty acid oxidation in insulin-resistant ob/ob mouse hearts.

4 September 2018

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Cardiac metabolism as a target for the treatment of heart failure

4 September 2018

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Altered myocardial fatty acid and glucose metabolism in idiopathic dilated cardiomyopathy.

4 September 2018

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Temporally regulated and tissue-specific gene manipulations in the adult and embryonic heart using a tamoxifen-inducible Cre protein

4 September 2018

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Myocardial fatty acid metabolism: independent predictor of left ventricular mass in hypertensive heart disease

4 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23624629

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Effects of moderate hypertension on cardiac function and metabolism in the rabbit

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23624629

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Fatty acid oxidation enzyme gene expression is downregulated in the failing heart

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23624629

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1152/AJPHEART.00877.2012

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23624629%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23624629%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

PubMed publication ID

23624629

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23624629%20AND%20SRC:MED&resulttype=core&format=json