Characterizing anti-HIV monoclonal antibodies and immune sera by defining the mechanism of neutralization. (Q37072702)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16720980%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

title

Characterizing anti-HIV monoclonal antibodies and immune sera by defining the mechanism of neutralization (English)

1 reference

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28 January 2020

0 references

1 reference

1 reference

Emma T Crooks

1

1 reference

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28 January 2020

Penny L Moore

2

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28 January 2020

Douglas Richman

3

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28 January 2020

James Robinson

4

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28 January 2020

Jeffrey A Crooks

5

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28 January 2020

Michael Franti

6

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28 January 2020

Norbert Schülke

7

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28 January 2020

James M Binley

8

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28 January 2020

language of work or name

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1 January 2005

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28 January 2020

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28 January 2020

volume

14

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28 January 2020

page(s)

101-113

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28 January 2020

issue

3-4

1 reference

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Nature of nonfunctional envelope proteins on the surface of human immunodeficiency virus type 1.

28 January 2020

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Evaluating the immunogenicity of a disulfide-stabilized, cleaved, trimeric form of the envelope glycoprotein complex of human immunodeficiency virus type 1

29 September 2017

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Cryptic nature of a conserved, CD4-inducible V3 loop neutralization epitope in the native envelope glycoprotein oligomer of CCR5-restricted, but not CXCR4-using, primary human immunodeficiency virus type 1 strains

29 September 2017

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Antigenic conservation and immunogenicity of the HIV coreceptor binding site

29 September 2017

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29 September 2017

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Functional mimicry of a human immunodeficiency virus type 1 coreceptor by a neutralizing monoclonal antibody

29 September 2017

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Identification of a new quaternary neutralizing epitope on human immunodeficiency virus type 1 virus particles

29 September 2017

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Broadly neutralizing anti-HIV antibody 4E10 recognizes a helical conformation of a highly conserved fusion-associated motif in gp41

29 September 2017

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Comparison of HIV Type 1 ADA gp120 monomers versus gp140 trimers as immunogens for the induction of neutralizing antibodies.

29 September 2017

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The cytoplasmic tail slows the folding of human immunodeficiency virus type 1 Env from a late prebundle configuration into the six-helix bundle

29 September 2017

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Comprehensive cross-clade neutralization analysis of a panel of anti-human immunodeficiency virus type 1 monoclonal antibodies

29 September 2017

1 reference

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Structure and mechanistic analysis of the anti-human immunodeficiency virus type 1 antibody 2F5 in complex with its gp41 epitope

29 September 2017

1 reference

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The V1/V2 domain of gp120 is a global regulator of the sensitivity of primary human immunodeficiency virus type 1 isolates to neutralization by antibodies commonly induced upon infection

29 September 2017

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Identifying epitopes of HIV-1 that induce protective antibodies

29 September 2017

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Binding of the 2F5 monoclonal antibody to native and fusion-intermediate forms of human immunodeficiency virus type 1 gp41: implications for fusion-inducing conformational changes.

29 September 2017

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The v3 loop is accessible on the surface of most human immunodeficiency virus type 1 primary isolates and serves as a neutralization epitope.

29 September 2017

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Progress in the development of an HIV vaccine

29 September 2017

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Access of antibody molecules to the conserved coreceptor binding site on glycoprotein gp120 is sterically restricted on primary human immunodeficiency virus type 1

29 September 2017

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Antibody domain exchange is an immunological solution to carbohydrate cluster recognition

29 September 2017

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A novel human antibody against human immunodeficiency virus type 1 gp120 is V1, V2, and V3 loop dependent and helps delimit the epitope of the broadly neutralizing antibody immunoglobulin G1 b12.

29 September 2017

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Human Immunodeficiency Virus Type 1 Env with an Intersubunit Disulfide Bond Engages Coreceptors but Requires Bond Reduction after Engagement To Induce Fusion

29 September 2017

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Redox-Triggered Infection by Disulfide-Shackled Human Immunodeficiency Virus Type 1 Pseudovirions

29 September 2017

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Rapid evolution of the neutralizing antibody response to HIV type 1 infection

29 September 2017

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Neutralization of human immunodeficiency virus type 1 by sCD4-17b, a single-chain chimeric protein, based on sequential interaction of gp120 with CD4 and coreceptor

29 September 2017

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Alternative conformations of HIV-1 V3 loops mimic beta hairpins in chemokines, suggesting a mechanism for coreceptor selectivity

29 September 2017

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Characterization of CD4-induced epitopes on the HIV type 1 gp120 envelope glycoprotein recognized by neutralizing human monoclonal antibodies

29 September 2017

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Sensitivity of HIV-1 to entry inhibitors correlates with envelope/coreceptor affinity, receptor density, and fusion kinetics

29 September 2017

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The crown and stem of the V3 loop play distinct roles in human immunodeficiency virus type 1 envelope glycoprotein interactions with the CCR5 coreceptor

29 September 2017

1 reference

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Oligomeric and conformational properties of a proteolytically mature, disulfide-stabilized human immunodeficiency virus type 1 gp140 envelope glycoprotein

29 September 2017

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Efficient isolation of novel human monoclonal antibodies with neutralizing activity against HIV-1 from transgenic mice expressing human Ig loci

29 September 2017

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The broadly neutralizing anti-human immunodeficiency virus type 1 antibody 2G12 recognizes a cluster of alpha1-->2 mannose residues on the outer face of gp120.

29 September 2017

1 reference

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The mannose-dependent epitope for neutralizing antibody 2G12 on human immunodeficiency virus type 1 glycoprotein gp120.

29 September 2017

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Dissection of human immunodeficiency virus type 1 entry with neutralizing antibodies to gp41 fusion intermediates

29 September 2017

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Truncation of the cytoplasmic domain induces exposure of conserved regions in the ectodomain of human immunodeficiency virus type 1 envelope protein

29 September 2017

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A variable region 3 (V3) mutation determines a global neutralization phenotype and CD4-independent infectivity of a human immunodeficiency virus type 1 envelope associated with a broadly cross-reactive, primary virus-neutralizing antibody response

29 September 2017

1 reference

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Broadly neutralizing antibodies targeted to the membrane-proximal external region of human immunodeficiency virus type 1 glycoprotein gp41.

29 September 2017

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Relationships between CD4 independence, neutralization sensitivity, and exposure of a CD4-induced epitope in a human immunodeficiency virus type 1 envelope protein

29 September 2017

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Increased neutralization sensitivity of CD4-independent human immunodeficiency virus variants

29 September 2017

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Immunogenicity and protective efficacy of oligomeric human immunodeficiency virus type 1 gp140.

29 September 2017

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A recombinant human immunodeficiency virus type 1 envelope glycoprotein complex stabilized by an intermolecular disulfide bond between the gp120 and gp41 subunits is an antigenic mimic of the trimeric virion-associated structure

29 September 2017

1 reference

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Sequential CD4-coreceptor interactions in human immunodeficiency virus type 1 Env function: soluble CD4 activates Env for coreceptor-dependent fusion and reveals blocking activities of antibodies against cryptic conserved epitopes on gp120.

29 September 2017

1 reference

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Stable exposure of the coreceptor-binding site in a CD4-independent HIV-1 envelope protein

29 September 2017

1 reference

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Comparison of the antibody repertoire generated in healthy volunteers following immunization with a monomeric recombinant gp120 construct derived from a CCR5/CXCR4-using human immunodeficiency virus type 1 isolate with sera from naturally infected i

29 September 2017

1 reference

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Antibodies with specificity to native gp120 and neutralization activity against primary human immunodeficiency virus type 1 isolates elicited by immunization with oligomeric gp160.

29 September 2017

1 reference

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Differential regulation of the antibody responses to Gag and Env proteins of human immunodeficiency virus type 1

29 September 2017

1 reference

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CD4-dependent, antibody-sensitive interactions between HIV-1 and its co-receptor CCR-5.

29 September 2017

1 reference

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CD4-induced interaction of primary HIV-1 gp120 glycoproteins with the chemokine receptor CCR-5.

29 September 2017

1 reference

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Antibody cross-competition analysis of the human immunodeficiency virus type 1 gp120 exterior envelope glycoprotein.

29 September 2017

1 reference

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Cryptic nature of envelope V3 region epitopes protects primary monocytotropic human immunodeficiency virus type 1 from antibody neutralization

29 September 2017

1 reference

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Development of the anti-gp120 antibody response during seroconversion to human immunodeficiency virus type 1

29 September 2017

1 reference

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Efficient neutralization of primary isolates of HIV-1 by a recombinant human monoclonal antibody

29 September 2017

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A conserved neutralizing epitope on gp41 of human immunodeficiency virus type 1

29 September 2017

1 reference

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Identification and characterization of conserved and variable regions in the envelope gene of HTLV-III/LAV, the retrovirus of AIDS.

29 September 2017

1 reference

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Synergistic interaction between ligands binding to the CD4 binding site and V3 domain of human immunodeficiency virus type I gp120

29 September 2017

1 reference

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Characterization of CD4-gp120 activation intermediates during human immunodeficiency virus type 1 syncytium formation

29 September 2017

1 reference

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Endoproteolytic cleavage of gp160 is required for the activation of human immunodeficiency virus

27 June 2018

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Spectrotype of anti-gp120 antibodies remains stable during the course of HIV disease

27 June 2018

1 reference

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Analysis of the neutralizing antibody response elicited in rabbits by repeated inoculation with trimeric HIV-1 envelope glycoproteins.

27 June 2018

1 reference

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HIV vaccine design and the neutralizing antibody problem

4 September 2018

1 reference

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4 September 2018

Identifiers

1 reference

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28 January 2020

1 reference