CD8+ T cells targeting a single immunodominant epitope are sufficient for elimination of established SV40 T antigen-induced brain tumors. (Q37074414)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18768900%20AND%20SRC:MED&resulttype=core&format=json

13 January 2020

title

CD8+ T cells targeting a single immunodominant epitope are sufficient for elimination of established SV40 T antigen-induced brain tumors (English)

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13 January 2020

8

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13 January 2020

author name string

Angela M Tatum

1

1 reference

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13 January 2020

Lawrence M Mylin

2

1 reference

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13 January 2020

Susan J Bender

3

1 reference

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13 January 2020

Matthew A Fischer

4

1 reference

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13 January 2020

Beth A Vigliotti

5

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13 January 2020

M Judith Tevethia

6

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13 January 2020

Satvir S Tevethia

7

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13 January 2020

language of work or name

English

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publication date

1 September 2008

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13 January 2020

published in

Journal of Immunology

1 reference

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13 January 2020

volume

181

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13 January 2020

issue

6

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13 January 2020

page(s)

4406-4417

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An SV40 VP1-derived epitope recognized by CD8+ T cells is naturally processed and presented by HLA-A*0201 and cross-reactive with human polyomavirus determinants

13 January 2020

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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A simian virus 40 large T-antigen segment containing amino acids 1 to 127 and expressed under the control of the rat elastase-1 promoter produces pancreatic acinar carcinomas in transgenic mice.

29 September 2017

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Class I–restricted Cross-Presentation of Exogenous Self-Antigens Leads to Deletion of Autoreactive CD8+ T Cells

29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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Simian virus 40 large T antigen contains two independent activities that cooperate with a ras oncogene to transform rat embryo fibroblasts

29 September 2017

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29 September 2017

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Transgenic mice harboring SV40 T-antigen genes develop characteristic brain tumors

29 September 2017

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29 September 2017

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Interferon gamma and tumor necrosis factor have a role in tumor regressions mediated by murine CD8+ tumor-infiltrating lymphocytes

29 September 2017

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Stroma is critical for preventing or permitting immunological destruction of antigenic cancer cells

29 September 2017

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Fine Specificity Analysis with Monoclonal Antibodies of Antigens Controlled by the Major Histocompatibility Complex and by the Qa/TL Region in Mice

29 September 2017

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Regression and inhibition of sarcoma growth by interference with a radiosensitive T-cell population

29 September 2017

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Cytotoxic T lymphocyte escape variants, induced mutations, and synthetic peptides define a dominant H-2Kb-restricted determinant in simian virus 40 tumor antigen

29 September 2017

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A critical requirement of interferon gamma-mediated angiostasis for tumor rejection by CD8+ T cells.

29 September 2017

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Organization, structure, and function of 95 kb of DNA spanning the murine T-cell receptor C alpha/C delta region.

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Anti-CD40 conditioning enhances the T(CD8) response to a highly tolerogenic epitope and subsequent immunotherapy of simian virus 40 T antigen-induced pancreatic tumors

27 June 2018

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IFN-gamma regulates donor CD8 T cell expansion, migration, and leads to apoptosis of cells of a solid tumor.

4 September 2018

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Host lymphodepletion augments T cell adoptive immunotherapy through enhanced intratumoral proliferation of effector cells

4 September 2018

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Initiation of immune responses in brain is promoted by local dendritic cells

4 September 2018

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Irradiation up-regulates CD80 expression through two different mechanisms in spleen B cells, B lymphoma cells, and dendritic cells

4 September 2018

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In vivo ligation of CD40 enhances priming against the endogenous tumor antigen and promotes CD8+ T cell effector function in SV40 T antigen transgenic mice.

4 September 2018

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4 September 2018

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4 September 2018

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4 September 2018

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4 September 2018

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gamma-Interferon plays a key role in T-cell-induced tumor regression.

4 September 2018

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4 September 2018

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Somatic recombination in a murine T-cell receptor gene

4 September 2018

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SV40 Transplantation Antigen: Relationship to SV40-specific Proteins

4 September 2018

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Demonstration of multiple antigenic sites of the SV40 transplantation rejection antigen by using cytotoxic T lymphocyte clones

4 September 2018

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12 December 2020

Clustering of antigenic sites recognized by cytotoxic T lymphocyte clones in the amino terminal half of SV40 T antigen

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Redundancy of direct priming and cross-priming in tumor-specific CD8+ T cell responses

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12 December 2020

Compromised anti-tumor responses in tumor necrosis factor-alpha knockout mice

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12 December 2020

Tumor regression after adoptive transfer of effector T cells is independent of perforin or Fas ligand (APO-1L/CD95L)

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12 December 2020

Early immunization induces persistent tumor-infiltrating CD8+ T cells against an immunodominant epitope and promotes lifelong control of pancreatic tumor progression in SV40 tumor antigen transgenic mice

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12 December 2020

Immortalization of primary mouse embryo fibroblasts with SV40 virions, viral DNA, and a subgenomic DNA fragment in a quantitative assay

1 reference

12 December 2020

Quantitation of CD8(+) T-lymphocyte responses to multiple epitopes from simian virus 40 (SV40) large T antigen in C57BL/6 mice immunized with SV40, SV40 T-antigen-transformed cells, or vaccinia virus recombinants expressing full-length T antigen or

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12 December 2020

Homeostatic proliferation as an isolated variable reverses CD8+ T cell anergy and promotes tumor rejection

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12 December 2020

In vitro mutagenesis of a putative DNA binding domain of SV40 large-T

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12 December 2020

Cassette vectors directing expression of T cell receptor genes in transgenic mice

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12 December 2020

Cutting Edge: CD8+ Effector T Cells Reject Tumors by Direct Antigen Recognition but Indirect Action on Host Cells

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12 December 2020

?-Irradiation facilitates the expression of adoptive immunity against established tumors by eliminating suppressor T cells

1 reference

12 December 2020

Cooperative interaction of B lymphocytes with antigen-specific helper T lymphocytes is MHC restricted

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12 December 2020

Differences in the effects of host suppression on the adoptive immunotherapy of subcutaneous and visceral tumors

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12 December 2020

Roles of tumour localization, second signals and cross priming in cytotoxic T-cell induction

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12 December 2020

10.4049/JIMMUNOL.181.6.4406

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18768900%20AND%20SRC:MED&resulttype=core&format=json

13 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18768900%20AND%20SRC:MED&resulttype=core&format=json

13 January 2020

PubMed publication ID

18768900

1 reference