LD Motif Recognition by Talin: Structure of the Talin-DLC1 Complex (Q37079846)

18 August 2017

LD Motif Recognition by Talin: Structure of the Talin-DLC1 Complex (English)

1 reference

18 August 2017

3

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27265849%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

Teresa B Almeida

5

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7 June 2020

Christoph Ballestrem

6

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7 June 2020

author name string

Thomas Zacharchenko

1

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7 June 2020

Xiaolan Qian

2

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7 June 2020

Devina Jethwa

4

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7 June 2020

David R Critchley

7

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7 June 2020

Douglas R Lowy

8

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7 June 2020

Igor L Barsukov

9

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7 June 2020

publication date

31 May 2016

1 reference

full work available at URL

18 August 2017

http://eprints.whiterose.ac.uk/103797/

content deliverer

White Rose Research Online

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published in

Structure

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7 June 2020

volume

24

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7 June 2020

issue

7

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7 June 2020

page(s)

1130-1141

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Vinculin controls talin engagement with the actomyosin machinery.

7 June 2020

cites work

1 reference

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Signaling networks that regulate cell migration

29 September 2017

1 reference

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Integrins and cancer: regulators of cancer stemness, metastasis, and drug resistance.

29 September 2017

1 reference

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Conformational activation of talin by RIAM triggers integrin-mediated cell adhesion

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4938799

Structural and mechanistic insights into the recruitment of talin by RIAM in integrin signaling

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4938799

How to find a leucine in a haystack? Structure, ligand recognition and regulation of leucine-aspartic acid (LD) motifs

29 September 2017

1 reference

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Mechanical activation of vinculin binding to talin locks talin in an unfolded conformation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4938799

The on-off relationship of Rho and Rac during integrin-mediated adhesion and cell migration

29 September 2017

1 reference

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Talins and kindlins: partners in integrin-mediated adhesion.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4938799

Structural studies on full-length talin1 reveal a compact auto-inhibited dimer: implications for talin activation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4938799

RIAM and Vinculin Binding to Talin Are Mutually Exclusive and Regulate Adhesion Assembly and Turnover

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4938799

Vinculin regulates the recruitment and release of core focal adhesion proteins in a force-dependent manner

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4938799

Tiam1 interaction with the PAR complex promotes talin-mediated Rac1 activation during polarized cell migration

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4938799

Integrin adhesions: who's on first? What's on second? Connections between FAK and talin

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4938799

Assembly and disassembly of cell matrix adhesions

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4938799

Finding the weakest link: exploring integrin-mediated mechanical molecular pathways

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4938799

FAK promotes recruitment of talin to nascent adhesions to control cell motility

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4938799

Full activity of the deleted in liver cancer 1 (DLC1) tumor suppressor depends on an LD-like motif that binds talin and focal adhesion kinase (FAK)

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4938799

Significance of talin in cancer progression and metastasis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4938799

Central Region of Talin Has a Unique Fold That Binds Vinculin and Actin

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4938799

The domain structure of talin: Residues 1815-1973 form a five-helix bundle containing a cryptic vinculin-binding site

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4938799

The Tensin-3 protein, including its SH2 domain, is phosphorylated by Src and contributes to tumorigenesis and metastasis

29 September 2017

1 reference

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Mechanical integration of actin and adhesion dynamics in cell migration

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4938799

Stretching single talin rod molecules activates vinculin binding

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4938799

Talin depletion reveals independence of initial cell spreading from integrin activation and traction

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4938799

RIAM activates integrins by linking talin to ras GTPase membrane-targeting sequences

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4938799

A periodic table of coiled-coil protein structures.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4938799

The structure of the C-terminal actin-binding domain of talin

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4938799

Structural and dynamic characterization of a vinculin binding site in the talin rod

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4938799

The structure of alpha-helical coiled coils

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4938799

Activation of a vinculin-binding site in the talin rod involves rearrangement of a five-helix bundle

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4938799

Molecular recognition of paxillin LD motifs by the focal adhesion targeting domain

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4938799

The focal adhesion targeting (FAT) region of focal adhesion kinase is a four-helix bundle that binds paxillin

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4938799

A vinculin binding domain from the talin rod unfolds to form a complex with the vinculin head.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4938799

10.1016/J.STR.2016.04.016

27 June 2018

Identifiers

DOI

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10.1016/J.STR.2016.04.016

7 June 2020

Altmetric DOI

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CORE ID

81993236

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Dimensions Publication ID

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7 June 2020

PubMed publication ID

27265849

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