Impact of basolateral multidrug resistance-associated protein (Mrp) 3 and Mrp4 on the hepatobiliary disposition of fexofenadine in perfused mouse livers. (Q37081457)

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scientific article published on 14 February 2008

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English	Impact of basolateral multidrug resistance-associated protein (Mrp) 3 and Mrp4 on the hepatobiliary disposition of fexofenadine in perfused mouse livers.	scientific article published on 14 February 2008

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scholarly article

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2 January 2020

Impact of basolateral multidrug resistance-associated protein (Mrp) 3 and Mrp4 on the hepatobiliary disposition of fexofenadine in perfused mouse livers (English)

1 reference

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2 January 2020

multiple drug resistance

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based on heuristic

inferred from title

2

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2 January 2020

Kim L.R. Brouwer

6

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2 January 2020

author name string

Xianbin Tian

1

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2 January 2020

Maciej J Zamek-Gliszczynski

3

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2 January 2020

Martin G Belinsky

4

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2 January 2020

Gary D Kruh

5

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2 January 2020

publication date

14 February 2008

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2 January 2020

Drug Metabolism and Disposition

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2 January 2020

36

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2 January 2020

911-915

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2 January 2020

5

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2 January 2020

Multidrug resistance-associated protein 2 is primarily responsible for the biliary excretion of fexofenadine in mice

1 reference

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29 September 2017

Roles of P-glycoprotein, Bcrp, and Mrp2 in biliary excretion of spiramycin in mice.

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Multidrug resistance proteins 2 and 3 provide alternative routes for hepatic excretion of morphine-glucuronides

1 reference

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Mice lacking multidrug resistance protein 3 show altered morphine pharmacokinetics and morphine-6-glucuronide antinociception

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29 September 2017

Analysis of the in vivo functions of Mrp3.

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Interactions between hepatic Mrp4 and Sult2a as revealed by the constitutive androstane receptor and Mrp4 knockout mice

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Mechanisms of impaired biliary excretion of acetaminophen glucuronide after acute phenobarbital treatment or phenobarbital pretreatment

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Characterization of the 5'-flanking region of the human multidrug resistance protein 2 (MRP2) gene and its regulation in comparison withthe multidrug resistance protein 3 (MRP3) gene

1 reference

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29 September 2017

OATP and P-glycoprotein transporters mediate the cellular uptake and excretion of fexofenadine

1 reference

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29 September 2017

Characterization of the human multidrug resistance protein isoform MRP3 localized to the basolateral hepatocyte membrane

1 reference

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29 September 2017

Hepatic expression of multidrug resistance-associated protein-like proteins maintained in eisai hyperbilirubinemic rats.

1 reference

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Multidrug resistance protein 4 protects bone marrow, thymus, spleen, and intestine from nucleotide analogue-induced damage.

1 reference

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The effect of short- and long-term administration of verapamil on the disposition of cytochrome P450 3A and P-glycoprotein substrates.

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3 September 2018

Effect of itraconazole on the pharmacokinetics and pharmacodynamics of fexofenadine in relation to the MDR1 genetic polymorphism

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3 September 2018

Modulation of hepatic canalicular or basolateral transport proteins alters hepatobiliary disposition of a model organic anion in the isolated perfused rat liver.

1 reference

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3 September 2018

P-glycoprotein plays a major role in the efflux of fexofenadine in the small intestine and blood-brain barrier, but only a limited role in its biliary excretion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2634847

3 September 2018

Multidrug resistance-associated protein 4 is up-regulated in liver but down-regulated in kidney in obstructive cholestasis in the rat.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2634847

3 September 2018

Cotransport of reduced glutathione with bile salts by MRP4 (ABCC4) localized to the basolateral hepatocyte membrane

1 reference

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3 September 2018

Pharmacokinetics of 5 (and 6)-carboxy-2',7'-dichlorofluorescein and its diacetate promoiety in the liver

1 reference

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3 September 2018

Grapefruit juice reduces the oral bioavailability of fexofenadine but not desloratadine

1 reference

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3 September 2018

Characterization of the transport properties of cloned rat multidrug resistance-associated protein 3 (MRP3).

1 reference

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3 September 2018

Altered hepatobiliary disposition of acetaminophen glucuronide in isolated perfused livers from multidrug resistance-associated protein 2-deficient TR(-) rats

1 reference

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12 December 2020

based on heuristic

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Altered hepatobiliary disposition of 5 (and 6)-carboxy-2',7'-dichlorofluorescein in Abcg2 (Bcrp1) and Abcc2 (Mrp2) knockout mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/18276836

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vivo use of the P450 inactivator 1-aminobenzotriazole in the rat: varied dosing route to elucidate gut and liver contributions to first-pass and systemic clearance

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mrp4-/- mice have an impaired cytoprotective response in obstructive cholestasis

1 reference

https://pubmed.ncbi.nlm.nih.gov/18276836

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evaluation of the role of multidrug resistance-associated protein (Mrp) 3 and Mrp4 in hepatic basolateral excretion of sulfate and glucuronide metabolites of acetaminophen, 4-methylumbelliferone, and harmol in Abcc3-/- and Abcc4-/- mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/18276836

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of inducible nature of MRP3 in rat liver

1 reference

https://pubmed.ncbi.nlm.nih.gov/18276836

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1124/DMD.107.019273

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2 January 2020

1 reference

Europe PubMed Central

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2 January 2020

1 reference

Europe PubMed Central

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2 January 2020

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