A critical role for IL-21 receptor signaling in the pathogenesis of systemic lupus erythematosus in BXSB-Yaa mice (Q37083674)

18 August 2017

A critical role for IL-21 receptor signaling in the pathogenesis of systemic lupus erythematosus in BXSB-Yaa mice (English)

1 reference

systemic lupus erythematosus

18 August 2017

0 references

1 reference

Jason A Bubier

1

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Herbert C. Morse

object named as

Herbert C Morse

6

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author name string

Thomas J Sproule

2

1 reference

18 August 2017

Oded Foreman

3

1 reference

18 August 2017

Rosanne Spolski

4

1 reference

18 August 2017

Daniel J Shaffer

5

1 reference

18 August 2017

Warren J Leonard

7

1 reference

18 August 2017

Derry C Roopenian

8

1 reference

18 August 2017

language of work or name

English

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publication date

21 January 2009

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18 August 2017

6

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Proceedings of the National Academy of Sciences of the United States of America

inferred from page(s)

published in

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18 August 2017

106

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18 August 2017

1518-1523

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18 August 2017

5

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describes a project that uses

18 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2635818/fullTextXML

inferred from PubMed Central ID database lookup

cites work

ICOS-dependent extrafollicular helper T cells elicit IgG production via IL-21 in systemic autoimmunity

1 reference

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A fundamental role for interleukin-21 in the generation of T follicular helper cells

29 September 2017

1 reference

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IL-21 and autoimmune disease--hypothesis and reality?

29 September 2017

1 reference

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Development and characterization of IL-21-producing CD4+ T cells

29 September 2017

1 reference

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T follicular helper (TFH) cells in normal and dysregulated immune responses

29 September 2017

1 reference

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Roquin represses autoimmunity by limiting inducible T-cell co-stimulator messenger RNA

29 September 2017

1 reference

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Interleukin 17-producing T helper cells and interleukin 17 orchestrate autoreactive germinal center development in autoimmune BXD2 mice

29 September 2017

1 reference

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Interleukin-21: Basic Biology and Implications for Cancer and Autoimmunity

29 September 2017

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Essential autocrine regulation by IL-21 in the generation of inflammatory T cells

29 September 2017

1 reference

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IL-21 initiates an alternative pathway to induce proinflammatory T(H)17 cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2635818

IL-6 programs T(H)-17 cell differentiation by promoting sequential engagement of the IL-21 and IL-23 pathways

29 September 2017

1 reference

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A Tlr7 translocation accelerates systemic autoimmunity in murine lupus

29 September 2017

1 reference

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Autoreactive B cell responses to RNA-related antigens due to TLR7 gene duplication

29 September 2017

1 reference

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Follicular B helper T cells in antibody responses and autoimmunity.

29 September 2017

1 reference

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A RING-type ubiquitin ligase family member required to repress follicular helper T cells and autoimmunity

29 September 2017

1 reference

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Synergy of IL-21 and IL-15 in regulating CD8+ T cell expansion and function.

29 September 2017

1 reference

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Regulation of B cell differentiation and plasma cell generation by IL-21, a novel inducer of Blimp-1 and Bcl-6

29 September 2017

1 reference

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IL-21 induces the functional maturation of murine NK cells

29 September 2017

1 reference

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Customized molecular phenotyping by quantitative gene expression and pattern recognition analysis

29 September 2017

1 reference

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A critical role for IL-21 in regulating immunoglobulin production

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2635818

Interleukin 21 and its receptor are involved in NK cell expansion and regulation of lymphocyte function

29 September 2017

1 reference

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Monocytosis in the BXSB model for systemic lupus erythematosus

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2635818

Selective autoantibody production by Yaa+ B cells in autoimmune Yaa(+)-Yaa- bone marrow chimeric mice

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2635818

A y chromosome associated factor in strain bxsb producing accelerated autoimmunity and lymphoproliferation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2635818

IL-21 has a pathogenic role in a lupus-prone mouse model and its blockade with IL-21R.Fc reduces disease progression.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2635818

IL-21 induces differentiation of human naive and memory B cells into antibody-secreting plasma cells.

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2635818

IL-21 and IL-21R are not required for development of Th17 cells and autoimmunity in vivo

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2635818

Cytokine-mediated regulation of human B cell differentiation into Ig-secreting cells: predominant role of IL-21 produced by CXCR5+ T follicular helper cells.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2635818

Treatment of BXSB-Yaa mice with IL-21R-Fc fusion protein minimally attenuates systemic lupus erythematosus.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2635818

Kinetics of human B cell behavior and amplification of proliferative responses following stimulation with IL-21.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2635818

Genetic association of interleukin-21 polymorphisms with systemic lupus erythematosus

3 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.0807309106

Lupus susceptibility loci map within regions of BXSB derived from the SB/Le parental strain

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.0807309106

The role of alpha beta+ T cells and homeostatic T cell proliferation in Y-chromosome-associated murine lupus

21 January 2018

1 reference

12 December 2020

The MHC class I-like IgG receptor controls perinatal IgG transport, IgG homeostasis, and fate of IgG-Fc-coupled drugs

1 reference

12 December 2020

Renal vascular complications of systemic lupus erythematosus

1 reference

12 December 2020

The Yaa gene-mediated acceleration of murine lupus: Yaa- T cells from non-autoimmune mice collaborate with Yaa+ B cells to produce lupus autoantibodies in vivo

1 reference

12 December 2020

beta2-microglobulin dependence of the lupus-like autoimmune syndrome of MRL-lpr mice

1 reference

12 December 2020

Hyperproliferation of BXSB B cells is linked to the Yaa allele

1 reference

12 December 2020

THE REPRODUCIBILITY OF SEMIQUANTITATIVE ANALYSES OF RENAL HISTOLOGY

1 reference

12 December 2020

Selective expansion of a monocyte subset expressing the CD11c dendritic cell marker in the Yaa model of systemic lupus erythematosus

1 reference

12 December 2020

Blockade of the interleukin-21/interleukin-21 receptor pathway ameliorates disease in animal models of rheumatoid arthritis

1 reference

12 December 2020

Monocytosis in BXSB mice is due to epistasis between Yaa and the telomeric region of chromosome 1 but does not drive the disease process

1 reference

12 December 2020

Cutting Edge: IL-21 Is Not Essential for Th17 Differentiation or Experimental Autoimmune Encephalomyelitis

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.0807309106

1 reference

18 August 2017

0 references

1 reference

18 August 2017

1 reference