Novel phosphorylation sites in the S. cerevisiae Cdc13 protein reveal new targets for telomere length regulation. (Q37084017)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23181431%20AND%20SRC:MED&resulttype=core&format=json

18 February 2020

title

Novel phosphorylation sites in the S. cerevisiae Cdc13 protein reveal new targets for telomere length regulation (English)

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18 February 2020

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2

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18 February 2020

author name string

Yun Wu

1

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18 February 2020

David H Perlman

3

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18 February 2020

Virginia A Zakian

4

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18 February 2020

Benjamin A Garcia

5

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18 February 2020

publication date

13 December 2012

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Journal of Proteome Research

18 February 2020

published in

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18 February 2020

volume

12

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18 February 2020

issue

1

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18 February 2020

page(s)

316-327

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The telomeric Cdc13 protein interacts directly with the telomerase subunit Est1 to bring it to telomeric DNA ends in vitro

18 February 2020

cites work

1 reference

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SUMOylation regulates telomere length homeostasis by targeting Cdc13.

29 September 2017

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Diverse protein kinase interactions identified by protein microarrays reveal novel connections between cellular processes

29 September 2017

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Structural bases of dimerization of yeast telomere protein Cdc13 and its interaction with the catalytic subunit of DNA polymerase α

29 September 2017

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Telomerase recruitment in Saccharomyces cerevisiae is not dependent on Tel1-mediated phosphorylation of Cdc13.

29 September 2017

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Cdc13 N-Terminal Dimerization, DNA Binding, and Telomere Length Regulation

29 September 2017

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De novo telomere formation is suppressed by the Mec1-dependent inhibition of Cdc13 accumulation at DNA breaks

29 September 2017

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29 September 2017

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Rapid Cdc13 turnover and telomere length homeostasis are controlled by Cdk1-mediated phosphorylation of Cdc13.

29 September 2017

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Distinct roles for yeast Stn1 in telomere capping and telomerase inhibition

29 September 2017

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Cdk1-dependent phosphorylation of Cdc13 coordinates telomere elongation during cell-cycle progression.

29 September 2017

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Inhibition of yeast telomerase action by the telomeric ssDNA-binding protein, Cdc13p

29 September 2017

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Decision tree-driven tandem mass spectrometry for shotgun proteomics

29 September 2017

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Tel1 kinase and subtelomere-bound Tbf1 mediate preferential elongation of short telomeres by telomerase in yeast.

29 September 2017

1 reference

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Telomerase and Tel1p preferentially associate with short telomeres in S. cerevisiae.

29 September 2017

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Increased association of telomerase with short telomeres in yeast.

29 September 2017

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Analysis of phosphorylation sites on proteins from Saccharomyces cerevisiae by electron transfer dissociation (ETD) mass spectrometry

29 September 2017

1 reference

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The telomerase-recruitment domain of the telomere binding protein Cdc13 is regulated by Mec1p/Tel1p-dependent phosphorylation.

29 September 2017

1 reference

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Regulation of telomere elongation by the cyclin-dependent kinase CDK1.

29 September 2017

1 reference

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Interaction of Saccharomyces Cdc13p with Pol1p, Imp4p, Sir4p and Zds2p is involved in telomere replication, telomere maintenance and cell growth control

29 September 2017

1 reference

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Absolute quantification of proteins and phosphoproteins from cell lysates by tandem MS

29 September 2017

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Stop and go extraction tips for matrix-assisted laser desorption/ionization, nanoelectrospray, and LC/MS sample pretreatment in proteomics

29 September 2017

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Delineation of the high-affinity single-stranded telomeric DNA-binding domain of Saccharomyces cerevisiae Cdc13.

29 September 2017

1 reference

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Cdc13 delivers separate complexes to the telomere for end protection and replication

29 September 2017

1 reference

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Cdc13 both positively and negatively regulates telomere replication

29 September 2017

1 reference

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Cdc13 cooperates with the yeast Ku proteins and Stn1 to regulate telomerase recruitment

29 September 2017

1 reference

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The Saccharomyces telomere-binding protein Cdc13p interacts with both the catalytic subunit of DNA polymerase alpha and the telomerase-associated est1 protein

29 September 2017

1 reference

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Identification of the single-strand telomeric DNA binding domain of the Saccharomyces cerevisiae Cdc13 protein

29 September 2017

1 reference

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Interactions of TLC1 (which encodes the RNA subunit of telomerase), TEL1, and MEC1 in regulating telomere length in the yeast Saccharomyces cerevisiae

29 September 2017

1 reference

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Sir proteins, Rif proteins, and Cdc13p bind Saccharomyces telomeres in vivo

29 September 2017

1 reference

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Regulation of Cdc2 activity by phosphorylation at T14/Y15

29 September 2017

1 reference

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Reverse transcriptase motifs in the catalytic subunit of telomerase

29 September 2017

1 reference

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Stn1, a new Saccharomyces cerevisiae protein, is implicated in telomere size regulation in association with Cdc13.

29 September 2017

1 reference

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Senescence mutants of Saccharomyces cerevisiae with a defect in telomere replication identify three additional EST genes.

29 September 2017

1 reference

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The Saccharomyces CDC13 protein is a single-strand TG1-3 telomeric DNA-binding protein in vitro that affects telomere behavior in vivo

29 September 2017

1 reference

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Regulatory roles of cyclin dependent kinase phosphorylation in cell cycle control

29 September 2017

1 reference

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Cdc13p: a single-strand telomeric DNA-binding protein with a dual role in yeast telomere maintenance

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3739059

Specific Association of Human Telomerase Activity with Immortal Cells and Cancer

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3739059

Single-stranded DNA arising at telomeres in cdc13 mutants may constitute a specific signal for the RAD9 checkpoint

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3739059

TLC1: template RNA component of Saccharomyces cerevisiae telomerase

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3739059

A mutant with a defect in telomere elongation leads to senescence in yeast

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3739059

The SCX/IMAC enrichment approach for global phosphorylation analysis by mass spectrometry

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3739059

Proteasome-dependent degradation of Est1p regulates the cell cycle-restricted assembly of telomerase in Saccharomyces cerevisiae

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3739059

Telomere length homeostasis is achieved via a switch between telomerase- extendible and -nonextendible states.

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3739059

TEL1, a gene involved in controlling telomere length in S. cerevisiae, is homologous to the human ataxia telangiectasia gene

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3739059

Early replication of short telomeres in budding yeast

3 September 2018

1 reference

12 December 2020

Tel1p Preferentially Associates with Short Telomeres to Stimulate Their Elongation

1 reference

12 December 2020

Delivery of yeast telomerase to a DNA break depends on the recruitment functions of Cdc13 and Est1

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12 December 2020

Saccharomyces telomeres acquire single-strand TG1-3 tails late in S phase

1 reference

12 December 2020

Telomerase-mediated telomere addition in vivo requires DNA primase and DNA polymerases alpha and delta.

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12 December 2020

Cell cycle restriction of telomere elongation

1 reference

12 December 2020

Est1p as a cell cycle-regulated activator of telomere-bound telomerase

1 reference

12 December 2020

Est1 and Cdc13 as comediators of telomerase access

1 reference

12 December 2020

DNA degradation at unprotected telomeres in yeast is regulated by the CDK1 (Cdc28/Clb) cell-cycle kinase

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12 December 2020

Identifiers

DOI

10.1021/PR300408V

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18 February 2020

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18 February 2020

PubMed publication ID

23181431

1 reference

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