Nanotechnology in vaccine delivery (Q37104199)

18 August 2017

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title

Nanotechnology in vaccine delivery (English)

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18 August 2017

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Laura J Peek

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18 August 2017

C Russell Middaugh

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2

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18 August 2017

Cory Berkland

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3

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18 August 2017

language of work or name

English

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publication date

7 February 2008

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Advanced Drug Delivery Reviews

18 August 2017

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18 August 2017

60

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18 August 2017

915-928

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18 August 2017

8

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A practical approach to the use of nanoparticles for vaccine delivery

18 August 2017

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12 December 2020

In vitro stimulation of CD8 and CD4 T cells by dendritic cells loaded with a complex of cholesterol-bearing hydrophobized pullulan and NY-ESO-1 protein: Identification of a new HLA-DR15-binding CD4 T-cell epitope.

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12 December 2020

Safety and immunogenicity of nonadjuvanted and MF59-adjuvanted influenza A/H9N2 vaccine preparations.

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12 December 2020

The prime-boost concept applied to HIV preventive vaccines

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12 December 2020

Accelerated immune response to DNA vaccines

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12 December 2020

Immunogenicity and protective efficacy of a tuberculosis DNA vaccine

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12 December 2020

A synthetic malaria vaccine elicits a potent CD8(+) and CD4(+) T lymphocyte immune response in humans. Implications for vaccination strategies.

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12 December 2020

Immunostimulating complexes (ISCOMs) for nasal vaccination

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12 December 2020

Biodegradable nanoparticles for drug and gene delivery to cells and tissue

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12 December 2020

Phase 1 safety and immunogenicity evaluation of a multiclade HIV-1 candidate vaccine delivered by a replication-defective recombinant adenovirus vector

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12 December 2020

Induction of WT1 (Wilms' tumor gene)-specific cytotoxic T lymphocytes by WT1 peptide vaccine and the resultant cancer regression

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12 December 2020

A recombinant glycoprotein vaccine for herpes simplex virus type 2: safety and immunogenicity [corrected]

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12 December 2020

Recombinant NY-ESO-1 protein with ISCOMATRIX adjuvant induces broad integrated antibody and CD4+ and CD8+ T cell responses in humans

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12 December 2020

Preparation of coated nanoparticles for a new mucosal vaccine delivery system

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12 December 2020

Safety and immunogenicity of adenovirus-vectored nasal and epicutaneous influenza vaccines in humans.

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12 December 2020

Vaccine technologies: view to the future

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12 December 2020

Recombinant viral vectors: cancer vaccines

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12 December 2020

Secretory immune responses in the mouse vagina after parenteral or intravaginal immunization with an immunostimulating complex (ISCOM)

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12 December 2020

Local tissue irritating effects and adjuvant activities of calcium phosphate and aluminium hydroxide with different physical properties

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12 December 2020

Clinical experience with plasmid DNA- and modified vaccinia virus Ankara-vectored human immunodeficiency virus type 1 clade A vaccine focusing on T-cell induction

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12 December 2020

Induction of Th1 type response by DNA vaccinations with N, M, and E genes against SARS-CoV in mice.

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12 December 2020

Phase 1 study of HPV16-specific immunotherapy with E6E7 fusion protein and ISCOMATRIX adjuvant in women with cervical intraepithelial neoplasia

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12 December 2020

Development of a preventive vaccine for Ebola virus infection in primates

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12 December 2020

Characterization of poly(D,L-lactic-co-glycolic acid) based nanoparticulate system for enhanced delivery of antigens to dendritic cells

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12 December 2020

Immunization of breast cancer patients using a synthetic sialyl-Tn glycoconjugate plus Detox adjuvant

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12 December 2020

MAGE-A1-, MAGE-A10-, and gp100-derived peptides are immunogenic when combined with granulocyte-macrophage colony-stimulating factor and montanide ISA-51 adjuvant and administered as part of a multipeptide vaccine for melanoma

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12 December 2020

Biodegradable nanoparticle delivery of a Th2-biased peptide for induction of Th1 immune responses

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12 December 2020

Differential protective efficacy of DNA vaccines expressing secreted proteins of Mycobacterium tuberculosis

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12 December 2020

Biodegradable poly(lactic-co-glycolic acid) microparticles for injectable delivery of vaccine antigens

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12 December 2020

Safety and efficacy of chimeric yellow Fever-dengue virus tetravalent vaccine formulations in nonhuman primates

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12 December 2020

Tetanus toxoid loaded nanoparticles from sulfobutylated poly(vinyl alcohol)-graft-poly(lactide-co-glycolide): evaluation of antibody response after oral and nasal application in mice

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12 December 2020

Lipid based particulate formulations for the delivery of antigen.

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12 December 2020

Polygene DNA vaccine induces a high level of protective effect against HIV-vaccinia virus challenge in mice

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12 December 2020

Induction of a cytotoxic T lymphocyte response by immunization with a malaria specific CTL peptide entrapped in biodegradable polymer microspheres

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12 December 2020

Clinical and immunologic responses to human immunodeficiency virus (HIV) type 1SF2 gp120 subunit vaccine combined with MF59 adjuvant with or without muramyl tripeptide dipalmitoyl phosphatidylethanolamine in non-HIV-infected human volunteers

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12 December 2020

Comparison of the safety, tolerability, and immunogenicity of a MF59-adjuvanted influenza vaccine and a non-adjuvanted influenza vaccine in non-elderly adults

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12 December 2020

Microparticles as vaccine adjuvants and delivery systems

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12 December 2020

The influence of protein solubilisation, conformation and size on the burst release from poly(lactide-co-glycolide) microspheres

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12 December 2020

Phase I/II study of immunotherapy with T-cell peptide epitopes in patients with stage IV melanoma

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12 December 2020

Aluminium compounds for use in vaccines

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12 December 2020

Positively charged liposome functions as an efficient immunoadjuvant in inducing cell-mediated immune response to soluble proteins

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12 December 2020

The adjuvanted influenza vaccines with novel adjuvants: experience with the MF59-adjuvanted vaccine

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12 December 2020

Intranasal immunisation with influenza-ISCOM induces strong mucosal as well as systemic antibody and cytotoxic T-lymphocyte responses

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12 December 2020

Recombinant DNA hepatitis B vaccine containing Pre-S components of the HBV coat protein--a preliminary study on immunogenicity

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12 December 2020

Chemical structure and biologic activity of bacterial and synthetic lipid A.

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12 December 2020

Inflexal V a trivalent virosome subunit influenza vaccine: production

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12 December 2020

Clinical experience with inactivated, virosomal influenza vaccine.

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12 December 2020

Calcium phosphate nanoparticle adjuvant

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12 December 2020

Safety and immunogenicity of a three-component blood-stage malaria vaccine in adults living in an endemic area of Papua New Guinea

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12 December 2020

Viral vectors for malaria vaccine development

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12 December 2020

Immunogenicity of four Plasmodium falciparum preerythrocytic antigens in Aotus lemurinus monkeys

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12 December 2020

Human hepatitis B vaccine from recombinant yeast

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12 December 2020

Liposomes as carriers of antigens and adjuvants

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12 December 2020

Montanide ISA 720 vaccines: quality control of emulsions, stability of formulated antigens, and comparative immunogenicity of vaccine formulations

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12 December 2020

Physiochemical and functional characterization of antigen proteins eluted from aluminum hydroxide adjuvant.

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12 December 2020

Immunopotentiating reconstituted influenza virosomes (IRIVs) and other adjuvants for improved presentation of small antigens

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12 December 2020

ISCOMATRIX adjuvant for antigen delivery

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12 December 2020

DNA-based therapeutics and DNA delivery systems: a comprehensive review

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12 December 2020

Progress in DNA-based heterologous prime-boost immunization strategies for malaria

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12 December 2020

Intranasal administration of a proteosome-influenza vaccine is well-tolerated and induces serum and nasal secretion influenza antibodies in healthy human subjects

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12 December 2020

Efficacy of a bivalent L1 virus-like particle vaccine in prevention of infection with human papillomavirus types 16 and 18 in young women: a randomised controlled trial

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12 December 2020

A randomized, double blind study in young healthy adults comparing cell mediated and humoral immune responses induced by influenza ISCOM? vaccines and conventional vaccines

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12 December 2020

Immunization by particle-mediated transfer of the granulocyte-macrophage colony-stimulating factor gene into autologous tumor cells in melanoma or sarcoma patients: report of a phase I/IB study

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12 December 2020

Toxicological hazards of inhaled nanoparticles--potential implications for drug delivery

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12 December 2020

Impact of pneumococcal conjugate vaccine on the prevention of invasive pneumococcal diseases

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12 December 2020

Virus-like particles: passport to immune recognition

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12 December 2020

In vivo and in vitro gene transfer to mammalian somatic cells by particle bombardment

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12 December 2020

Antibody responses to preS components after immunization of children with low doses of BioHepB.

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12 December 2020

Augmentation of human influenza A virus-specific cytotoxic T lymphocyte memory by influenza vaccine and adjuvanted carriers (ISCOMS).

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12 December 2020

Haemophilus influenzae type b conjugate vaccines: a review of efficacy data

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12 December 2020

Macrophagic myofasciitis lesions assess long-term persistence of vaccine-derived aluminium hydroxide in muscle

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12 December 2020

Randomized phase IIB trial of BLP25 liposome vaccine in stage IIIB and IV non-small-cell lung cancer

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12 December 2020

Mechanisms of stimulation of the immune response by aluminum adjuvants

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12 December 2020

CpG oligodeoxynucleotide enhances immunity against blood-stage malaria infection in mice parenterally immunized with a yeast-expressed 19 kDa carboxyl-terminal fragment of Plasmodium yoelii merozoite surface protein-1 (MSP1(19)) formulated in oil-ba

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12 December 2020

Safety and immunogenicity of a Proteosome™-trivalent inactivated influenza vaccine, given nasally to healthy adults

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12 December 2020

Adenovirus vector-based vaccines for human immunodeficiency virus type 1.

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12 December 2020

Synthetic DNA delivery systems

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12 December 2020

Uptake and adjuvant activity of orally delivered saponin and ISCOM vaccines

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12 December 2020

Phase I testing of a malaria vaccine composed of hepatitis B virus core particles expressing Plasmodium falciparum circumsporozoite epitopes.

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12 December 2020

A randomized, controlled study in adults of the immunogenicity of a novel hepatitis B vaccine containing MF59 adjuvant

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12 December 2020

Intranasal Protollin/F1-V vaccine elicits respiratory and serum antibody responses and protects mice against lethal aerosolized plague infection

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12 December 2020

Generation and characterization of DNA vaccines targeting the nucleocapsid protein of severe acute respiratory syndrome coronavirus

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12 December 2020

Partition of polysaccharide-coated liposomes in aqueous two-phase systems

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12 December 2020

Monophosphoryl lipid A (MPL) formulations for the next generation of vaccines

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12 December 2020

Antibody response against NY-ESO-1 in CHP-NY-ESO-1 vaccinated patients

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12 December 2020

Long-lived cytotoxic T lymphocyte memory in mucosal tissues after mucosal but not systemic immunization

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12 December 2020

Der p 1 peptide on virus-like particles is safe and highly immunogenic in healthy adults

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12 December 2020

Antibody protects macaques against vaginal challenge with a pathogenic R5 simian/human immunodeficiency virus at serum levels giving complete neutralization in vitro

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12 December 2020

Safety of DNA and modified vaccinia virus Ankara vaccines against liver-stage P. falciparum malaria in non-immune volunteers

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12 December 2020

Active specific immunotherapy for melanoma: phase I trial of allogeneic lysates and a novel adjuvant

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12 December 2020

Safety and enhanced immunogenicity of a hepatitis B core particle Plasmodium falciparum malaria vaccine formulated in adjuvant Montanide ISA 720 in a phase I trial

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12 December 2020

Certification of polio eradication: process and lessons learned.

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12 December 2020

Montanide ISA 720 and 51: a new generation of water in oil emulsions as adjuvants for human vaccines

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12 December 2020

Influenza virosomes as an efficient system for adjuvanted vaccine delivery.

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12 December 2020

Studies on the O antigen of Salmonella typhosa. V. Enhancement of antibody response to protein antigens by the purified lipopolysaccharide

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12 December 2020

Phase I study of the BLP25 (MUC1 peptide) liposomal vaccine for active specific immunotherapy in stage IIIB/IV non-small-cell lung cancer

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12 December 2020

Immunogenicity of a recombinant human cytomegalovirus gB vaccine in seronegative toddlers

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12 December 2020

Calcium phosphate nanoparticles induce mucosal immunity and protection against herpes simplex virus type 2.

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12 December 2020

Enhanced immunogenicity of CD4(+) t-cell responses and protective efficacy of a DNA-modified vaccinia virus Ankara prime-boost vaccination regimen for murine tuberculosis

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12 December 2020

The development of vaccines against SARS corona virus in mice and SCID-PBL/hu mice

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12 December 2020

Effect of vaccination with 3 recombinant asexual-stage malaria antigens on initial growth rates of Plasmodium falciparum in non-immune volunteers

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12 December 2020

Generation of PSA-reactive effector cells after vaccination with a PSA-based vaccine in patients with prostate cancer

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12 December 2020

Biodegradable microparticles as controlled release antigen delivery systems.

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12 December 2020

Effects of adsorption to aluminum salt adjuvants on the structure and stability of model protein antigens

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12 December 2020

A canarypox vector-expressing cytomegalovirus (CMV) phosphoprotein 65 induces long-lasting cytotoxic T cell responses in human CMV-seronegative subjects

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12 December 2020

Effective induction of simian immunodeficiency virus-specific cytotoxic T lymphocytes in macaques by using a multiepitope gene and DNA prime-modified vaccinia virus Ankara boost vaccination regimen

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12 December 2020

Induction of protective cytotoxic T cells to murine cytomegalovirus by using a nonapeptide and a human-compatible adjuvant (Montanide ISA 720).

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12 December 2020

Structure and adsorption properties of commercial calcium phosphate adjuvant

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12 December 2020

A novel hydrophobized polysaccharide/oncoprotein complex vaccine induces in vitro and in vivo cellular and humoral immune responses against HER2-expressing murine sarcomas.

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12 December 2020

Biodegradable and biocompatible poly(DL-lactide-co-glycolide) microspheres as an adjuvant for staphylococcal enterotoxin B toxoid which enhances the level of toxin-neutralizing antibodies.

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12 December 2020

Chapter 1: Human papillomavirus and cervical cancer--burden and assessment of causality

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12 December 2020

Human phase I vaccine trials of 3 recombinant asexual stage malaria antigens with Montanide ISA720 adjuvant

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12 December 2020

Controlled release microparticles for vaccine development

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12 December 2020

The virosome concept for influenza vaccines

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12 December 2020

Vaccination with recombinant fusion proteins incorporating Toll-like receptor ligands induces rapid cellular and humoral immunity

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12 December 2020

Induction of multifunctional human immunodeficiency virus type 1 (HIV-1)-specific T cells capable of proliferation in healthy subjects by using a prime-boost regimen of DNA- and modified vaccinia virus Ankara-vectored vaccines expressing HIV-1 Gag c

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12 December 2020

A phase I trial in HIV negative healthy volunteers evaluating the effect of potent adjuvants on immunogenicity of a recombinant gp120W61D derived from dual tropic R5X4 HIV-1ACH320.

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12 December 2020

Protollin: a novel adjuvant for intranasal vaccines

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12 December 2020

Improved immunogenicity in mice of a mammalian cell-derived recombinant hepatitis B vaccine containing pre-S1 and pre-S2 antigens as compared with conventional yeast-derived vaccines

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12 December 2020

Sustained efficacy up to 4.5 years of a bivalent L1 virus-like particle vaccine against human papillomavirus types 16 and 18: follow-up from a randomised control trial

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12 December 2020

Liposomal vaccines: clinical status and immunological presentation for humoral and cellular immunity.

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12 December 2020

ISCOMs and other saponin based adjuvants

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12 December 2020

MF59. Design and evaluation of a safe and potent adjuvant for human vaccines

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12 December 2020

Dendritic cells internalize vaccine adjuvant after intramuscular injection

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12 December 2020

C57Bl/6 mice are protected from respiratory syncytial virus (RSV) challenge and IL-5 associated pulmonary eosinophilic infiltrates following intranasal immunization with Protollin-eRSV vaccine

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12 December 2020

Antiviral cytotoxic T lymphocyte induction and vaccination

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12 December 2020

Increased immunogenicity of the MF59-adjuvanted influenza vaccine compared to a conventional subunit vaccine in elderly subjects

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12 December 2020

Nasal immunization with subunit proteosome influenza vaccines induces serum HAI, mucosal IgA and protection against influenza challenge

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12 December 2020

Adenoviral vectors for mucosal vaccination against infectious diseases.

1 reference

12 December 2020

Aluminum compounds as vaccine adjuvants

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12 December 2020

Immunization of human HIV-seronegative volunteers with recombinant p17/p24:Ty virus-like particles elicits HIV-1 p24-specific cellular and humoral immune responses.

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12 December 2020

A phase I clinical trial of a multi-epitope polypeptide TAB9 combined with Montanide ISA 720 adjuvant in non-HIV-1 infected human volunteers

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12 December 2020

Active Immunization of Human Ovarian Cancer Patients Against a Common Carcinoma (Thomsen-Friedenreich) Determinant Using a Synthetic Carbohydrate Antigen

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12 December 2020

Nasal inoculation of an adenovirus vector encoding 11 tandem repeats of Abeta1-6 upregulates IL-10 expression and reduces amyloid load in a Mo/Hu APPswe PS1dE9 mouse model of Alzheimer's disease

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12 December 2020

Safety and immunogenicity of a proteosome-Shigella flexneri 2a lipopolysaccharide vaccine administered intranasally to healthy adults

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12 December 2020

Responses of well-differentiated nasal epithelial cells exposed to particles: role of the epithelium in airway inflammation

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12 December 2020

Studies on the toxicities of aluminium hydroxide and calcium phosphate as immunological adjuvants for vaccines

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12 December 2020

Humoral, mucosal, and cellular immune responses to oral Norwalk virus-like particles in volunteers

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12 December 2020

Phase I trial in humans of an oil-based adjuvant SEPPIC MONTANIDE ISA 720.

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12 December 2020

Enhancement of the effectiveness of electroporation-augmented cutaneous DNA vaccination by a particulate adjuvant.

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12 December 2020

Microparticle-based technologies for vaccines

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12 December 2020

A prime-boost approach to HIV preventive vaccine using a recombinant canarypox virus expressing glycoprotein 160 (MN) followed by a recombinant glycoprotein 160 (MN/LAI). The AGIS Group, and l'Agence Nationale de Recherche sur le SIDA.

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12 December 2020

Design and preclinical evaluation of a multigene human immunodeficiency virus type 1 subtype C DNA vaccine for clinical trial

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12 December 2020

DNA vaccines: protective immunizations by parenteral, mucosal, and gene-gun inoculations

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12 December 2020

Protection against tetanus by needle-free inoculation of adenovirus-vectored nasal and epicutaneous vaccines

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12 December 2020

Presentation of a major histocompatibility complex class 1-binding peptide by monocyte-derived dendritic cells incorporating hydrophobized polysaccharide-truncated HER2 protein complex: implications for a polyvalent immuno-cell therapy

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12 December 2020

Preclinical and clinical progress of particle-mediated DNA vaccines for infectious diseases

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12 December 2020

Prophylactic quadrivalent human papillomavirus (types 6, 11, 16, and 18) L1 virus-like particle vaccine in young women: a randomised double-blind placebo-controlled multicentre phase II efficacy trial

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12 December 2020

A single dose of an ISCOM influenza vaccine induces long-lasting protective immunity against homologous challenge infection but fails to protect Cynomolgus macaques against distant drift variants of influenza A (H3N2) viruses.

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12 December 2020

Vaccines: past, present and future

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12 December 2020

Anti-mycobacterial immunity induced by a single injection of M. leprae Hsp65-encoding plasmid DNA in biodegradable microparticles.

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12 December 2020

Nanoparticulate systems for nasal delivery of drugs: a real improvement over simple systems?

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12 December 2020

Enhanced T-cell immunogenicity of plasmid DNA vaccines boosted by recombinant modified vaccinia virus Ankara in humans

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12 December 2020

Safety and immunogenicity of adjuvanted and unadjuvanted subunit influenza vaccines administered intranasally to healthy adults

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12 December 2020

Persistent subcutaneous nodules in children hyposensitized with aluminium-containing allergen extracts.

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12 December 2020

Intranasal vaccination with ISCOMATRIX adjuvanted influenza vaccine.

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12 December 2020

Viral vectored immunocontraception: screening of multiple fertility antigens using murine cytomegalovirus as a vaccine vector.

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12 December 2020

Adjuvant activity of non-toxic Quillaja saponaria Molina components for use in ISCOM matrix

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12 December 2020

Safety and tolerability of recombinant modified vaccinia virus Ankara expressing an HIV-1 gag/multiepitope immunogen (MVA.HIVA) in HIV-1-infected persons receiving combination antiretroviral therapy

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12 December 2020

Control of a mucosal challenge and prevention of AIDS by a multiprotein DNA/MVA vaccine

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12 December 2020

Monophosphoryl lipid A as an adjuvant. Past experiences and new directions

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12 December 2020

Self-assembled hydrogel nanoparticle of cholesterol-bearing pullulan as a carrier of protein drugs: complexation and stabilization of insulin

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12 December 2020

Immunisation policies--successes, failures and the future

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12 December 2020

Liposomal formulations of synthetic MUC1 peptides: effects of encapsulation versus surface display of peptides on immune responses.

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12 December 2020

Immunostimulatory colloidal delivery systems for cancer vaccines.

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12 December 2020

Encapsulation of peptides in biodegradable microspheres prolongs their MHC class-I presentation by dendritic cells and macrophages in vitro

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12 December 2020

Enhanced immune response with a combination of alum and biodegradable nanoparticles containing tetanus toxoid

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12 December 2020

Prevention and control of meningococcal disease. Recommendations of the Advisory Committee on Immunization Practices (ACIP)

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12 December 2020

Liposomes as vehicles for vaccines

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12 December 2020

10.1016/J.ADDR.2007.05.017

Identifiers

DOI

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18 August 2017

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