Hyperhomocysteinemia exacerbates Alzheimer's disease pathology by way of the β-amyloid fibrinogen interaction (Q37104293)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27090576%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

title

Hyperhomocysteinemia exacerbates Alzheimer's disease pathology by way of the β-amyloid fibrinogen interaction (English)

1 reference

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2 April 2020

0 references

0 references

4

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2 April 2020

Sidney Strickland

6

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2 April 2020

Erin H Norris

7

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2 April 2020

author name string

Y C Chung

1

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2 April 2020

A Kruyer

2

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2 April 2020

Y Yao

3

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2 April 2020

A Richards

5

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2 April 2020

publication date

13 June 2016

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Journal of Thrombosis and Haemostasis

2 April 2020

published in

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2 April 2020

volume

14

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2 April 2020

page(s)

1442-1452

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2 April 2020

issue

7

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describes a project that uses

2 April 2020

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4949110/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

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Fibrinogen and beta-amyloid association alters thrombosis and fibrinolysis: a possible contributing factor to Alzheimer's disease

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Diet-induced hyperhomocysteinemia increases amyloid-beta formation and deposition in a mouse model of Alzheimer's disease

14 September 2017

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29 September 2017

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29 September 2017

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27 June 2018

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27 June 2018

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3 September 2018

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Spatial learning and memory impairment and increased locomotion in a transgenic amyloid precursor protein mouse model of Alzheimer's disease.

3 September 2018

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Converging perturbed microvasculature and microglial clusters characterize Alzheimer disease brain.

3 September 2018

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3 September 2018

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Mutations in cystathionine beta-synthase or methylenetetrahydrofolate reductase gene increase N-homocysteinylated protein levels in humans

3 September 2018

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B-vitamin deprivation induces hyperhomocysteinemia and brain S-adenosylhomocysteine, depletes brain S-adenosylmethionine, and enhances PS1 and BACE expression and amyloid-beta deposition in mice.

3 September 2018

1 reference

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Plasma fibrinogen is associated with cognitive decline and risk for dementia in patients with mild cognitive impairment.

3 September 2018

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Impaired spatial memory in APP-overexpressing mice on a homocysteinemia-inducing diet.

3 September 2018

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Modification of fibrinogen by homocysteine thiolactone increases resistance to fibrinolysis: a potential mechanism of the thrombotic tendency in hyperhomocysteinemia.

3 September 2018

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Fibrinogen is associated with an increased risk of Alzheimer disease and vascular dementia.

3 September 2018

1 reference

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Matrix-fibrinogen enhances wound closure by increasing both cell proliferation and migration

3 September 2018

1 reference

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Elevated plasma homocysteine leads to alterations in fibrin clot structure and stability: implications for the mechanism of thrombosis in hyperhomocysteinemia

3 September 2018

1 reference

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Converging pathogenic mechanisms in vascular and neurodegenerative dementia.

3 September 2018

1 reference

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Cerebral amyloid angiopathy and cognitive function: the HAAS autopsy study.

3 September 2018

1 reference

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Early-onset amyloid deposition and cognitive deficits in transgenic mice expressing a double mutant form of amyloid precursor protein 695.

3 September 2018

1 reference

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Nutritionally independent B12 deficiency and Alzheimer disease.

3 September 2018

1 reference

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3 September 2018

Identifiers

DOI

10.1111/JTH.13340

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27090576%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27090576%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

1 reference