Aflibercept in wet AMD: specific role and optimal use. (Q37109788)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23990705%20AND%20SRC:MED&resulttype=core&format=json

8 March 2020

1 reference

20 August 2020

Aflibercept in wet AMD: specific role and optimal use (English)

1 reference

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Kuhnt-Junius degeneration

8 March 2020

main subject

7 references

25 April 2019

31 July 2019

28 September 2019

20 November 2019

15 December 2019

21 December 2019

20 August 2020

cell surface receptor

1 reference

31 July 2019

1 reference

28 September 2019

1 reference

20 November 2019

1 reference

15 December 2019

1 reference

21 December 2019

vascular endothelial growth factor A

1 reference

20 August 2020

1 reference

1

1 reference

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8 March 2020

Ciro Costagliola

6

1 reference

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8 March 2020

author name string

F Morescalchi

2

1 reference

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8 March 2020

S Duse

3

1 reference

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8 March 2020

F Parmeggiani

4

1 reference

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8 March 2020

E Gambicorti

5

1 reference

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8 March 2020

language of work or name

English

0 references

publication date

5 August 2013

8 references

25 April 2019

31 July 2019

28 September 2019

20 November 2019

15 December 2019

21 December 2019

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23990705%20AND%20SRC:MED&resulttype=core&format=json

8 March 2020

20 August 2020

Drug Design, Development and Therapy

8 references

25 April 2019

31 July 2019

28 September 2019

20 November 2019

15 December 2019

21 December 2019

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23990705%20AND%20SRC:MED&resulttype=core&format=json

8 March 2020

20 August 2020

7

1 reference

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8 March 2020

page(s)

711-722

1 reference

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Creative Commons Attribution-NonCommercial

8 March 2020

copyright license

7 references

25 April 2019

31 July 2019

28 September 2019

20 November 2019

15 December 2019

21 December 2019

20 August 2020

on focus list of Wikimedia project

ScienceSource

0 references

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Primary End Point (Six Months) Results of the Ranibizumab for Edema of the mAcula in diabetes (READ-2) study

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Intravitreal bevacizumab has initial clinical benefit lasting eight weeks in eyes with neovascular age-related macular degeneration.

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Tachyphylaxis after intravitreal bevacizumab for exudative age-related macular degeneration

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Pegaptanib sodium for neovascular age-related macular degeneration: third-year safety results of the VEGF Inhibition Study in Ocular Neovascularisation (VISION) trial

14 September 2017

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14 September 2017

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Ranibizumab versus verteporfin for neovascular age-related macular degeneration.

14 September 2017

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Ranibizumab for neovascular age-related macular degeneration

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14 September 2017

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Processing of VEGF-A by matrix metalloproteinases regulates bioavailability and vascular patterning in tumors

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14 September 2017

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Mice without uPA, tPA, or plasminogen genes are resistant to experimental choroidal neovascularization

14 September 2017

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VEGF-TRAP(R1R2) suppresses choroidal neovascularization and VEGF-induced breakdown of the blood-retinal barrier

14 September 2017

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Vascular endothelial growth factor (VEGF) stimulates neurogenesis in vitro and in vivo

14 September 2017

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VEGF-Trap: a VEGF blocker with potent antitumor effects

14 September 2017

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14 September 2017

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Lymphatic endothelium: a new frontier of metastasis research

14 September 2017

1 reference

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Vascular endothelial growth factor/vascular permeability factor expression in a mouse model of retinal neovascularization

14 September 2017

1 reference

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The diabetic retinopathy study and the early treatment diabetic retinopathy study.

14 September 2017

1 reference

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Vascular endothelial growth factor is a secreted angiogenic mitogen

14 September 2017

1 reference

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Nucleotide sequence and expression of a novel human receptor-type tyrosine kinase gene (flt) closely related to the fms family

14 September 2017

1 reference

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A receptor tyrosine kinase cDNA isolated from a population of enriched primitive hematopoietic cells and exhibiting close genetic linkage to c-kit

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3749085

Identification of a new endothelial cell growth factor receptor tyrosine kinase

14 September 2017

1 reference

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FLT4 receptor tyrosine kinase contains seven immunoglobulin-like loops and is expressed in multiple human tissues and cell lines

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3749085

The fms-like tyrosine kinase, a receptor for vascular endothelial growth factor

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3749085

A Phase IIIb study to evaluate the safety of ranibizumab in subjects with neovascular age-related macular degeneration

14 September 2017

1 reference

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Vascular endothelial growth factor acts as a survival factor for newly formed retinal vessels and has implications for retinopathy of prematurity

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3749085

Binding and neutralization of vascular endothelial growth factor (VEGF) and related ligands by VEGF Trap, ranibizumab and bevacizumab

29 September 2017

1 reference

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Vascular endothelial growth factor induces expression of the antiapoptotic proteins Bcl-2 and A1 in vascular endothelial cells

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3749085

Neovasculature induced by vascular endothelial growth factor is fenestrated.

27 June 2018

1 reference

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Developmental expression of binding sites and messenger ribonucleic acid for vascular endothelial growth factor suggests a role for this protein in vasculogenesis and angiogenesis

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3749085

Characterization of the receptors for vascular endothelial growth factor

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3749085

Bevacizumab vs ranibizumab-an appraisal of the evidence from CATT and IVAN.

27 June 2018

1 reference

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VEGF Trap-Eye for macular oedema secondary to central retinal vein occlusion: 6-month results of the phase III GALILEO study.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3749085

Intravitreal aflibercept injection for macular edema secondary to central retinal vein occlusion: 1-year results from the phase 3 COPERNICUS study

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3749085

Intravitreal aflibercept (VEGF trap-eye) in wet age-related macular degeneration.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3749085

Vascular endothelial growth factor Trap-Eye for macular edema secondary to central retinal vein occlusion: six-month results of the phase 3 COPERNICUS study.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3749085

Incidence of legal blindness from age-related macular degeneration in denmark: year 2000 to 2010.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3749085

Systemic adverse drug reactions secondary to anti-VEGF intravitreal injection in patients with neovascular age-related macular degeneration.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3749085

Intravitreal bevacizumab for treatment-naive patients with subfoveal occult choroidal neovascularization secondary to age-related macular degeneration: a 12-month follow-up study

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3749085

A phase I study of intravitreal vascular endothelial growth factor trap-eye in patients with neovascular age-related macular degeneration.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3749085

To investigate the prevalence of polypoidal choroidal vasculopathy in presumed age-related peripapillary subretinal neovascular membranes.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3749085

A variable-dosing regimen with intravitreal ranibizumab for neovascular age-related macular degeneration: year 2 of the PrONTO Study

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3749085

Is there tachyphylaxis to intravitreal anti-vascular endothelial growth factor pharmacotherapy in age-related macular degeneration?

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3749085

Predicted biological activity of intravitreal VEGF Trap.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3749085

A phase I trial of an IV-administered vascular endothelial growth factor trap for treatment in patients with choroidal neovascularization due to age-related macular degeneration.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3749085

Year 2 efficacy results of 2 randomized controlled clinical trials of pegaptanib for neovascular age-related macular degeneration.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3749085

Pegaptanib for neovascular age-related macular degeneration

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3749085

Polypoidal choroidal vasculopathy: incidence, demographic features, and clinical characteristics

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3749085

Augmentation of transvascular transport of macromolecules and nanoparticles in tumors using vascular endothelial growth factor.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3749085

VEGF contributes to postnatal neovascularization by mobilizing bone marrow-derived endothelial progenitor cells

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3749085

Increased microvascular permeability and endothelial fenestration induced by vascular endothelial growth factor

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3749085

Efficacy and safety of monthly versus quarterly ranibizumab treatment in neovascular age-related macular degeneration: the EXCITE study

3 September 2018

1 reference

12 December 2020

Aflibercept: AVE 0005, AVE 005, AVE0005, VEGF Trap - Regeneron, VEGF Trap (R1R2), VEGF Trap-Eye

1 reference

12 December 2020

Randomized, double-masked, sham-controlled trial of ranibizumab for neovascular age-related macular degeneration: PIER Study year 1

1 reference

12 December 2020

The 1-year results of CLEAR-IT 2, a phase 2 study of vascular endothelial growth factor trap-eye dosed as-needed after 12-week fixed dosing

1 reference

12 December 2020

Vascular endothelial growth factor induces rapid phosphorylation of tight junction proteins occludin and zonula occluden 1. A potential mechanism for vascular permeability in diabetic retinopathy and tumors

1 reference

12 December 2020

INTRAOCULAR PHARMACOKINETICS AFTER A SINGLE INTRAVITREAL INJECTION OF 1.5 mg VERSUS 3.0 mg OF BEVACIZUMAB IN HUMANS

1 reference

12 December 2020

Primary endpoint results of a phase II study of vascular endothelial growth factor trap-eye in wet age-related macular degeneration

1 reference

12 December 2020

Identifiers

DOI

10.2147/DDDT.S40215

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23990705%20AND%20SRC:MED&resulttype=core&format=json

8 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23990705%20AND%20SRC:MED&resulttype=core&format=json

8 March 2020

1 reference