Inhibition of DNA double-strand break repair by the Ku heterodimer in mrx mutants of Saccharomyces cerevisiae. (Q37109884)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18992851%20AND%20SRC:MED&resulttype=core&format=json

26 December 2019

title

Inhibition of DNA double-strand break repair by the Ku heterodimer in mrx mutants of Saccharomyces cerevisiae (English)

1 reference

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26 December 2019

main subject

Saccharomyces cerevisiae

1 reference

3

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26 December 2019

4

L Kevin Lewis

1 reference

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26 December 2019

author name string

Brian M Wasko

series ordinal

1

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26 December 2019

Cory L Holland

series ordinal

2

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26 December 2019

publication date

18 November 2008

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26 December 2019

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26 December 2019

volume

8

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26 December 2019

issue

2

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26 December 2019

page(s)

162-169

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Methylating agents and DNA repair responses: Methylated bases and sources of strand breaks

26 December 2019

cites work

1 reference

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Mechanism of homologous recombination: mediators and helicases take on regulatory functions

14 September 2017

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DNA double-strand break repair: all's well that ends well

14 September 2017

1 reference

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Suppression of gross chromosomal rearrangements by yKu70-yKu80 heterodimer through DNA damage checkpoints

14 September 2017

1 reference

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Nonhomologous end joining in yeast

14 September 2017

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Ku: a multifunctional protein involved in telomere maintenance

14 September 2017

1 reference

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Extratelomeric functions of telomerase.

14 September 2017

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Mechanism of DNA double-strand break repair by non-homologous end joining

14 September 2017

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Human Ku70/80 interacts directly with hTR, the RNA component of human telomerase

14 September 2017

1 reference

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Regulation of homologous integration in yeast by the DNA repair proteins Ku70 and RecQ.

14 September 2017

1 reference

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Non-homologous end-joining factors of Saccharomyces cerevisiae

14 September 2017

1 reference

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EXO1-A multi-tasking eukaryotic nuclease.

14 September 2017

1 reference

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Yeast telomerase RNA: a flexible scaffold for protein subunits

14 September 2017

1 reference

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Regulation of telomerase by telomeric proteins

14 September 2017

1 reference

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Telomerase, telomerase inhibition, and cancer

14 September 2017

1 reference

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Role of the nuclease activity of Saccharomyces cerevisiae Mre11 in repair of DNA double-strand breaks in mitotic cells.

14 September 2017

1 reference

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Radiation-induced DNA damage: formation, measurement, and biochemical features

14 September 2017

1 reference

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Nucleolar protein PinX1p regulates telomerase by sequestering its protein catalytic subunit in an inactive complex lacking telomerase RNA

14 September 2017

1 reference

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The Rad52-Rad59 complex interacts with Rad51 and replication protein A.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2647851

Ku interacts with telomerase RNA to promote telomere addition at native and broken chromosome ends

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2647851

Competition between the Rad50 complex and the Ku heterodimer reveals a role for Exo1 in processing double-strand breaks but not telomeres

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2647851

Positive and Negative Roles of Homologous Recombination in the Maintenance of Genome Stability in Saccharomyces cerevisiae

14 September 2017

1 reference

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Protective mechanisms against the antitumor agent bleomycin: lessons from Saccharomyces cerevisiae

14 September 2017

1 reference

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Human Ku70/80 associates physically with telomerase through interaction with hTERT

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2647851

Characterization of RAD51-independent break-induced replication that acts preferentially with short homologous sequences

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2647851

Maintenance of genome stability in Saccharomyces cerevisiae

14 September 2017

1 reference

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Transformation of yeast by lithium acetate/single-stranded carrier DNA/polyethylene glycol method

14 September 2017

1 reference

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The Mre11 complex: at the crossroads of dna repair and checkpoint signalling

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2647851

Essential regions of Saccharomyces cerevisiae telomerase RNA: separate elements for Est1p and Est2p interaction

14 September 2017

1 reference

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Differential suppression of DNA repair deficiencies of Yeast rad50, mre11 and xrs2 mutants by EXO1 and TLC1 (the RNA component of telomerase).

14 September 2017

1 reference

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Homologous recombinational repair of double-strand breaks in yeast is enhanced by MAT heterozygosity through yKU-dependent and -independent mechanisms.

14 September 2017

1 reference

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Interaction of human Ku70 with TRF2

14 September 2017

1 reference

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Tying up loose ends: nonhomologous end-joining in Saccharomyces cerevisiae

14 September 2017

1 reference

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The Mre11-Rad50-Xrs2 protein complex facilitates homologous recombination-based double-strand break repair in Saccharomyces cerevisiae

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2647851

Repair of endonuclease-induced double-strand breaks in Saccharomyces cerevisiae: essential role for genes associated with nonhomologous end-joining.

14 September 2017

1 reference

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Relocalization of telomeric Ku and SIR proteins in response to DNA strand breaks in yeast

14 September 2017

1 reference

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MEC1-dependent redistribution of the Sir3 silencing protein from telomeres to DNA double-strand breaks

14 September 2017

1 reference

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Saccharomyces Ku70, mre11/rad50 and RPA proteins regulate adaptation to G2/M arrest after DNA damage

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2647851

Requirement for end-joining and checkpoint functions, but not RAD52-mediated recombination, after EcoRI endonuclease cleavage of Saccharomyces cerevisiae DNA

14 September 2017

1 reference

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Designer deletion strains derived from Saccharomyces cerevisiae S288C: a useful set of strains and plasmids for PCR-mediated gene disruption and other applications

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2647851

Mutations in two Ku homologs define a DNA end-joining repair pathway in Saccharomyces cerevisiae

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2647851

Recombination during transformation as a source of chimeric mammalian artificial chromosomes in yeast (YACs)

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2647851

TLC1: template RNA component of Saccharomyces cerevisiae telomerase

14 September 2017

1 reference

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A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiae

14 September 2017

1 reference

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Requirement of the Mre11 complex and exonuclease 1 for activation of the Mec1 signaling pathway.

14 September 2017

1 reference

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Telomerase subunit overexpression suppresses telomere-specific checkpoint activation in the yeast yku80 mutant

29 September 2017

1 reference

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Functional characterization of yeast telomerase RNA dimerization.

27 June 2018

1 reference

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RSC mobilizes nucleosomes to improve accessibility of repair machinery to the damaged chromatin

3 September 2018

1 reference

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Double-strand breaks trigger MRX- and Mec1-dependent, but Tel1-independent, checkpoint activation.

3 September 2018

1 reference

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The function of a stem-loop in telomerase RNA is linked to the DNA repair protein Ku.

3 September 2018

1 reference

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Telomere maintenance is dependent on activities required for end repair of double-strand breaks

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2647851

hTERT associates with human telomeres and enhances genomic stability and DNA repair

3 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18992851

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.DNAREP.2008.09.010

1 reference

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26 December 2019

1 reference

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26 December 2019

PubMed publication ID

18992851

1 reference