Autism-associated mutations in ProSAP2/Shank3 impair synaptic transmission and neurexin-neuroligin-mediated transsynaptic signaling. (Q37117518)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23100419%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

title

Autism-associated mutations in ProSAP2/Shank3 impair synaptic transmission and neurexin-neuroligin-mediated transsynaptic signaling (English)

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16 February 2020

0 references

Andreas M. Grabrucker

3

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16 February 2020

Juliette E Cheyne

6

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16 February 2020

8

Johanna M Montgomery

1 reference

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16 February 2020

author name string

Magali H Arons

1

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16 February 2020

Charlotte J Thynne

2

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16 February 2020

Dong Li

4

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16 February 2020

Michael Schoen

5

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16 February 2020

Tobias M Boeckers

7

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16 February 2020

Craig C Garner

9

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16 February 2020

language of work or name

English

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publication date

1 October 2012

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16 February 2020

published in

Journal of Neuroscience

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16 February 2020

volume

32

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16 February 2020

issue

43

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16 February 2020

page(s)

14966-14978

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SHANK1 Deletions in Males with Autism Spectrum Disorder

16 February 2020

cites work

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The neurexin ligands, neuroligins and leucine-rich repeat transmembrane proteins, perform convergent and divergent synaptic functions in vivo

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Postsynaptic ProSAP/Shank scaffolds in the cross-hair of synaptopathies.

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Autism-linked neuroligin-3 R451C mutation differentially alters hippocampal and cortical synaptic function

14 September 2017

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Importance of Shank3 protein in regulating metabotropic glutamate receptor 5 (mGluR5) expression and signaling at synapses

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Haploinsufficiency of the autism-associated Shank3 gene leads to deficits in synaptic function, social interaction, and social communication

14 September 2017

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Common circuit defect of excitatory-inhibitory balance in mouse models of autism

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LRRTMs and neuroligins bind neurexins with a differential code to cooperate in glutamate synapse development

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Mutations in the SHANK2 synaptic scaffolding gene in autism spectrum disorder and mental retardation

14 September 2017

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A neuroligin-4 missense mutation associated with autism impairs neuroligin-4 folding and endoplasmic reticulum export

14 September 2017

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Postsynaptic Neuroligin1 regulates presynaptic maturation

14 September 2017

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A synaptic trek to autism

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Synaptic SAP97 isoforms regulate AMPA receptor dynamics and access to presynaptic glutamate

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14 September 2017

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14 September 2017

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14 September 2017

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14 September 2017

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14 September 2017

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14 September 2017

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14 September 2017

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14 September 2017

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14 September 2017

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14 September 2017

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14 September 2017

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The complexity of PDZ domain-mediated interactions at glutamatergic synapses: a case study on neuroligin

14 September 2017

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14 September 2017

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Linkage of the actin cytoskeleton to the postsynaptic density via direct interactions of Abp1 with the ProSAP/Shank family

14 September 2017

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14 September 2017

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14 September 2017

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Molecular characterisation of the 22q13 deletion syndrome supports the role of haploinsufficiency of SHANK3/PROSAP2 in the major neurological symptoms

14 September 2017

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14 September 2017

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14 September 2017

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ProSAP/Shank proteins - a family of higher order organizing molecules of the postsynaptic density with an emerging role in human neurological disease

14 September 2017

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Regulation of dendritic spine morphology and synaptic function by Shank and Homer

14 September 2017

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Neuroligin expressed in nonneuronal cells triggers presynaptic development in contacting axons

14 September 2017

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Homer: a link between neural activity and glutamate receptor function

14 September 2017

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Binding of neuroligins to PSD-95

14 September 2017

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Homer: a protein that selectively binds metabotropic glutamate receptors

14 September 2017

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SAP90, a rat presynaptic protein related to the product of the Drosophila tumor suppressor gene dlg-A.

14 September 2017

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Short-term synaptic plasticity

14 September 2017

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The rat brain postsynaptic density fraction contains a homolog of the Drosophila discs-large tumor suppressor protein

14 September 2017

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Autism: towards an integration of clinical, genetic, neuropsychological, and neurobiological perspectives

14 September 2017

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Modulation of synaptic transmission and long-term potentiation: effects on paired pulse facilitation and EPSC variance in the CA1 region of the hippocampus

29 September 2017

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SAP97 directs NMDA receptor spine targeting and synaptic plasticity

27 June 2018

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Novel de novo SHANK3 mutation in autistic patients

3 September 2018

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Transsynaptic signaling by postsynaptic synapse-associated protein 97.

3 September 2018

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Shank expression is sufficient to induce functional dendritic spine synapses in aspiny neurons.

3 September 2018

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Temporal appearance of the presynaptic cytomatrix protein bassoon during synaptogenesis

3 September 2018

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12 December 2020

Nonuniform probability of glutamate release at a hippocampal synapse

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12 December 2020

Assembly of new individual excitatory synapses: time course and temporal order of synaptic molecule recruitment

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12 December 2020

Development of neuronal polarity: GAP-43 distinguishes axonal from dendritic growth cones

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12 December 2020

10.1523/JNEUROSCI.2215-12.2012

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23100419%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23100419%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

PubMed publication ID

23100419

1 reference