T-box transcription factor T-bet, a key player in a unique type of B-cell activation essential for effective viral clearance (Q37117949)

18 August 2017

T-box transcription factor T-bet, a key player in a unique type of B-cell activation essential for effective viral clearance (English)

1 reference

18 August 2017

Philippa Marrack

5

0 references

Kira Rubtsova

series ordinal

1

object named as

Kira Rubtsova

1 reference

18 August 2017

4

John W Kappler

1 reference

18 August 2017

3

Linda F van Dyk

1 reference

18 August 2017

Anatoly V Rubtsov

2

1 reference

PMCID

3752276

18 August 2017

language of work or name

English

0 references

publication date

6 August 2013

1 reference

Proceedings of the National Academy of Sciences of the United States of America

18 August 2017

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18 August 2017

110

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18 August 2017

34

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18 August 2017

E3216-24

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Dynamic regulation of the structure and functions of integrin adhesions

18 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3752276

TLR7 drives accumulation of ABCs and autoantibody production in autoimmune-prone mice

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3752276

Accelerated and improved quantification of lymphocytic choriomeningitis virus (LCMV) titers by flow cytometry

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3752276

Divergent transcriptional programming of class-specific B cell memory by T-bet and RORα

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3752276

Murine gammaherpesvirus 68 infection protects lupus-prone mice from the development of autoimmunity

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3752276

Age-associated B cells: are they the key to understanding why autoimmune diseases are more prevalent in women?

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3752276

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3752276

A B-cell subset uniquely responsive to innate stimuli accumulates in aged mice

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3752276

Toll-like receptor 7 (TLR7)-driven accumulation of a novel CD11c⁺ B-cell population is important for the development of autoimmunity

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3752276

Toll-like receptor driven B cell activation in the induction of systemic autoimmunity

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3752276

Cutting edge: Hierarchy of maturity of murine memory B cell subsets

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3752276

Integrin CD11b negatively regulates TLR-triggered inflammatory responses by activating Syk and promoting degradation of MyD88 and TRIF via Cbl-b

14 September 2017

1 reference

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Ras activation of Erk restores impaired tonic BCR signaling and rescues immature B cell differentiation

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3752276

Runx3 and T-box proteins cooperate to establish the transcriptional program of effector CTLs

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3752276

Endothelial cells support persistent gammaherpesvirus 68 infection

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3752276

Gammaherpesvirus modulation of mouse adenovirus type 1 pathogenesis

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3752276

Murine cytomegalovirus encodes a stable intron that facilitates persistent replication in the mouse

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3752276

The T-box transcription factor T-bet in immunity and autoimmunity

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3752276

Transcription factor T-bet regulates inflammatory arthritis through its function in dendritic cells

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3752276

The adjuvant activity of CpG DNA requires T-bet expression in dendritic cells

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3752276

FcgammaRIV: a novel FcR with distinct IgG subclass specificity

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3752276

Induction of IgG2a class switching in B cells by IL-27.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3752276

Loss of T-bet, but not STAT1, prevents the development of experimental autoimmune encephalomyelitis

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3752276

Control of Effector CD8 + T Cell Function by the Transcription Factor Eomesodermin

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3752276

T-bet regulates T-independent IgG2a class switching

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3752276

CpG directly induces T-bet expression and inhibits IgG1 and IgE switching in B cells

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3752276

T-bet regulates IgG class switching and pathogenic autoantibody production

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3752276

Chromatin-IgG complexes activate B cells by dual engagement of IgM and Toll-like receptors

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3752276

T-bet is rapidly induced by interferon-gamma in lymphoid and myeloid cells

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3752276

Increased efficacy of the immunoglobulin G2a subclass in antibody-mediated protection against lactate dehydrogenase-elevating virus-induced polioencephalomyelitis revealed with switch mutants

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3752276

T cells compete for access to antigen-bearing antigen-presenting cells

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3752276

Interferon-gamma is required for lupus-like disease and lymphoaccumulation in MRL-lpr mice

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3752276

Cytokine production in the immune response to murine gammaherpesvirus 68.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3752276

Virally induced modulation of murine IgG antibody subclasses

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3752276

Neutrophil and monocyte cell surface p150,95 has iC3b-receptor (CR4) activity resembling CR3

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3752276

Toll-like receptor 7-dependent loss of B cell tolerance in pathogenic autoantibody knockin mice

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3752276

Divergent immunoglobulin g subclass activity through selective Fc receptor binding

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3752276

IFN-gamma receptor signaling is essential for the initiation, acceleration, and destruction of autoimmune kidney disease in MRL-Fas(lpr) mice.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3752276

Importance of immunoglobulin isotype in human antibody-dependent, cell-mediated cytotoxicity directed by murine monoclonal antibodies

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3752276

Universal vaccine against influenza virus: linking TLR signaling to anti-viral protection

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3752276

Integrin CD11c contributes to monocyte adhesion with CD11b in a differential manner and requires Src family kinase activity

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3752276

Memory B cell survival and function in the absence of secreted antibody and immune complexes on follicular dendritic cells.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3752276

Direct effects of T-bet and MHC class I expression, but not STAT1, on peripheral NK cell maturation.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3752276

T-box transcription-factor-deficient mice display increased joint pathology and failure of infection control during staphylococcal arthritis

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3752276

T-bet regulates the terminal maturation and homeostasis of NK and Valpha14i NKT cells.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3752276

In human B cells, IL-12 triggers a cascade of molecular events similar to Th1 commitment.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3752276

Analysis of the virus-specific and nonspecific B cell response to a persistent B-lymphotropic gammaherpesvirus

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3752276

T-bet is a STAT1-induced regulator of IL-12R expression in naïve CD4+ T cells

3 September 2018

1 reference

12 December 2020

The role of T-bet in B cells

1 reference

12 December 2020

Activation of autoreactive B cells by CpG dsDNA

1 reference

12 December 2020

IFN-gamma receptor deletion prevents autoantibody production and glomerulonephritis in lupus-prone (NZB x NZW)F1 mice

1 reference

12 December 2020

Interferon-gamma and B cell stimulatory factor-1 reciprocally regulate Ig isotype production

1 reference

12 December 2020

IFN-gamma is essential for the development of autoimmune glomerulonephritis in MRL/Ipr mice

1 reference

12 December 2020

A functional B cell receptor transgene allows efficient IL-7-independent maturation of B cell precursors

1 reference

12 December 2020

Stat1-dependent synergistic activation of T-bet for IgG2a production during early stage of B cell activation

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.1312348110

1 reference

18 August 2017

0 references

1 reference

18 August 2017

1 reference

PMCID

3752276