Antimalarial Benzoxaboroles Target Plasmodium falciparum Leucyl-tRNA Synthetase (Q37120074)

18 August 2017

Antimalarial Benzoxaboroles Target Plasmodium falciparum Leucyl-tRNA Synthetase (English)

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18 August 2017

Plasmodium falciparum

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antimalarial

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author

Stephen Anthony Cusack

16

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18 August 2017

17

Philip J Rosenthal

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18 August 2017

Ebere Sonoiki

1

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18 August 2017

Andres Palencia

2

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18 August 2017

Denghui Guo

3

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18 August 2017

Vida Ahyong

4

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18 August 2017

Chen Dong

5

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18 August 2017

Xianfeng Li

6

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18 August 2017

Vincent S Hernandez

7

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18 August 2017

Yong-Kang Zhang

8

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18 August 2017

Wai Choi

9

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18 August 2017

Jiri Gut

10

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18 August 2017

Jennifer Legac

11

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18 August 2017

Roland Cooper

12

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18 August 2017

M R K Alley

13

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18 August 2017

Yvonne R Freund

14

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18 August 2017

Joseph DeRisi

15

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18 August 2017

language of work or name

English

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publication date

6 June 2016

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18 August 2017

10

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Antimicrobial Agents and Chemotherapy

inferred from page(s)

published in

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18 August 2017

60

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18 August 2017

8

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18 August 2017

4886-4895

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Impact of antimalarial treatment and chemoprevention on the drug sensitivity of malaria parasites isolated from ugandan children

18 August 2017

1 reference

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Analogs of natural aminoacyl-tRNA synthetase inhibitors clear malaria in vivo

14 September 2017

1 reference

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1 reference

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14 September 2017

1 reference

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Discovery of a potent benzoxaborole-based anti-pneumococcal agent targeting leucyl-tRNA synthetase

14 September 2017

1 reference

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The interplay between drug resistance and fitness in malaria parasites

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1 reference

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Asexual populations of the human malaria parasite, Plasmodium falciparum, use a two-step genomic strategy to acquire accurate, beneficial DNA amplifications

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1 reference

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1 reference

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1 reference

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Uneven spread of cis- and trans-editing aminoacyl-tRNA synthetase domains within translational compartments of P. falciparum

14 September 2017

1 reference

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Halofuginone and other febrifugine derivatives inhibit prolyl-tRNA synthetase

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1 reference

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14 September 2017

1 reference

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Protein translation in Plasmodium parasites.

14 September 2017

1 reference

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SCYX-7158, an orally-active benzoxaborole for the treatment of stage 2 human African trypanosomiasis

14 September 2017

1 reference

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Therapeutic potential of boron-containing compounds

14 September 2017

1 reference

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1 reference

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Design, synthesis, and structure-activity relationship of Trypanosoma brucei leucyl-tRNA synthetase inhibitors as antitrypanosomal agents

14 September 2017

1 reference

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Boron-containing inhibitors of synthetases

14 September 2017

1 reference

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Validation of isoleucine utilization targets in Plasmodium falciparum

14 September 2017

1 reference

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Synthesis and structure-activity relationships of novel benzoxaboroles as a new class of antimalarial agents

14 September 2017

1 reference

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Inhibition of eukaryotic translation elongation by cycloheximide and lactimidomycin

14 September 2017

1 reference

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Crystal structures of the human and fungal cytosolic Leucyl-tRNA synthetase editing domains: A structural basis for the rational design of antifungal benzoxaboroles

14 September 2017

1 reference

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Aminoacyl-tRNA synthesis and translational quality control

14 September 2017

1 reference

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Ultrafast and memory-efficient alignment of short DNA sequences to the human genome

14 September 2017

1 reference

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PlasmoDB: a functional genomic database for malaria parasites

14 September 2017

1 reference

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An antifungal agent inhibits an aminoacyl-tRNA synthetase by trapping tRNA in the editing site

14 September 2017

1 reference

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Recent progress on the topical therapy of onychomycosis

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1 reference

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Likelihood-enhanced fast translation functions

14 September 2017

1 reference

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Refinement of macromolecular structures by the maximum-likelihood method

14 September 2017

1 reference

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1 reference

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Structural and mechanistic basis of pre- and posttransfer editing by leucyl-tRNA synthetase

14 September 2017

1 reference

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14 September 2017

1 reference

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14 September 2017

1 reference

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Aminoacyl-tRNA synthetases

27 June 2018

1 reference

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27 June 2018

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3 September 2018

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Stage-specific antimalarial activity of cysteine protease inhibitors

3 September 2018

1 reference

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A conserved threonine within Escherichia coli leucyl-tRNA synthetase prevents hydrolytic editing of leucyl-tRNALeu

3 September 2018

1 reference

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3 September 2018

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In vitro and in vivo antimalarial activities of a non-glycosidic 18-membered macrolide antibiotic, borrelidin, against drug-resistant strains of Plasmodia

3 September 2018

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PubMed

https://pubmed.ncbi.nlm.nih.gov/27270277

12 December 2020

inferred from PubMed ID database lookup

Synthesis and SAR of novel benzoxaboroles as a new class of β-lactamase inhibitors

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27270277

12 December 2020

inferred from PubMed ID database lookup

Processing of X-ray diffraction data collected in oscillation mode

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27270277

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1128/AAC.00820-16

1 reference

18 August 2017

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18 August 2017

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