Mitochondrial DNA instability and metabolic shift in human cancers. (Q37139830)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19333428%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

review article

2 references

5 July 2021

Mitochondrial DNA instability and metabolic shift in human cancers (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19333428%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

1 reference

20 September 2020

1 reference

14 September 2019

1 reference

20 October 2020

1 reference

8 February 2021

1 reference

5 July 2021

Somatic mutation

1 reference

PubMed publication ID

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19333428%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

Yau-Huei Wei

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19333428%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

author name string

Hsin-Chen Lee

series ordinal

1

1 reference

18 August 2017

Yau-Huei Wei

series ordinal

2

1 reference

18 August 2017

language of work or name

English

0 references

publication date

23 February 2009

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19333428%20AND%20SRC:MED&resulttype=core&format=json

International Journal of Molecular Sciences

25 January 2020

1 February 2009

4 references

20 September 2020

20 October 2020

8 February 2021

5 July 2021

10 references

3 April 2019

20 June 2019

30 June 2019

2 August 2019

14 September 2019

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19333428%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

20 September 2020

20 October 2020

8 February 2021

5 July 2021

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19333428%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

issue

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19333428%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

page(s)

674-701

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19333428%20AND%20SRC:MED&resulttype=core&format=json

Creative Commons Attribution

25 January 2020

copyright license

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3 April 2019

20 June 2019

30 June 2019

2 August 2019

14 September 2019

20 September 2020

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8 February 2021

5 July 2021

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on focus list of Wikimedia project

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14 September 2017

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14 September 2017

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Mitochondrial DNA mutations and mitochondrial DNA depletion in breast cancer

14 September 2017

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14 September 2017

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14 September 2017

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14 September 2017

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14 September 2017

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14 September 2017

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14 September 2017

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14 September 2017

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14 September 2017

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14 September 2017

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14 September 2017

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Control region mutations and the 'common deletion' are frequent in the mitochondrial DNA of patients with esophageal squamous cell carcinoma

14 September 2017

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14 September 2017

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14 September 2017

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14 September 2017

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14 September 2017

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14 September 2017

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14 September 2017

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14 September 2017

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14 September 2017

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14 September 2017

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14 September 2017

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14 September 2017

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14 September 2017

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14 September 2017

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14 September 2017

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14 September 2017

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CREB activation induced by mitochondrial dysfunction is a new signaling pathway that impairs cell proliferation

14 September 2017

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Inhibition of early apoptotic events by Akt/PKB is dependent on the first committed step of glycolysis and mitochondrial hexokinase

14 September 2017

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14 September 2017

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Mitochondria-to-nucleus stress signaling induces phenotypic changes, tumor progression and cell invasion

14 September 2017

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14 September 2017

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14 September 2017

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14 September 2017

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14 September 2017

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mtDNA and the origin of Caucasians: identification of ancient Caucasian-specific haplogroups, one of which is prone to a recurrent somatic duplication in the D-loop region

14 September 2017

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Somatic mitochondrial mutation in gastric cancer

14 September 2017

1 reference

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Sequence and organization of the human mitochondrial genome

14 September 2017

1 reference

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Mitochondrial DNA somatic mutations are frequent in nasopharyngeal carcinoma

14 September 2017

1 reference

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Resistance of mtDNA-depleted cells to apoptosis

14 September 2017

1 reference

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Increased mitochondrial DNA induces acquired docetaxel resistance in head and neck cancer cells

14 September 2017

1 reference

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Depletion of mitochondrial DNA by ethidium bromide treatment inhibits the proliferation and tumorigenesis of T47D human breast cancer cells

14 September 2017

1 reference

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Mitochondrial DNA determines androgen dependence in prostate cancer cell lines.

14 September 2017

1 reference

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Mitochondria-to-nucleus stress signaling in mammalian cells: nature of nuclear gene targets, transcription regulation, and induced resistance to apoptosis

14 September 2017

1 reference

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Chloramphenicol-induced mitochondrial stress increases p21 expression and prevents cell apoptosis through a p21-dependent pathway.

14 September 2017

1 reference

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Down-regulation of mitochondrial F1F0-ATP synthase in human colon cancer cells with induced 5-fluorouracil resistance

14 September 2017

1 reference

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Mitochondrial DNA mutations in light-associated skin tumors.

14 September 2017

1 reference

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Increase of mitochondria and mitochondrial DNA in response to oxidative stress in human cells

14 September 2017

1 reference

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Mitochondrial DNA determines the cellular response to cancer therapeutic agents

29 September 2017

1 reference

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Retrograde Ca2+ signaling in C2C12 skeletal myocytes in response to mitochondrial genetic and metabolic stress: a novel mode of inter-organelle crosstalk

29 September 2017

1 reference

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The mitochondrial DNA common deletion is present in most basal and squamous cell carcinoma samples isolated by laser capture microdissection but generally at reduced rather than increased levels.

29 September 2017

1 reference

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Increase in mitochondrial mass in human fibroblasts under oxidative stress and during replicative cell senescence

27 June 2018

1 reference

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Diminished tumorigenic phenotype after depletion of mitochondrial DNA.

27 June 2018

1 reference

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Repair of oxidative damage to nuclear and mitochondrial DNA in mammalian cells

27 June 2018

1 reference

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Detection of mitochondrial genome depletion by a novel cDNA in renal cell carcinoma

27 June 2018

1 reference

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Enzymatic and spectral analysis of cytochrome oxidase in adult and fetal rat liver and Morris hepatoma 3924A.

27 June 2018

1 reference

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Functional significance of mitochondrial bound hexokinase in tumor cell metabolism. Evidence for preferential phosphorylation of glucose by intramitochondrially generated ATP.

27 June 2018

1 reference

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Transformation of rat fibroblasts by FSV rapidly increases glucose transporter gene transcription.

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2660656

Low copy number and low oxidative damage of mitochondrial DNA are associated with tumor progression in lung cancer tissues after neoadjuvant chemotherapy

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2660656

Correlation between copy number of mitochondrial DNA and clinico-pathologic parameters of hepatocellular carcinoma

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2660656

Mitochondrial DNA mutations in oral squamous cell carcinoma.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2660656

Mitochondrial DNA mutations in renal cell carcinomas revealed no general impact on energy metabolism

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2660656

Clinical value of mitochondrial mutations in colorectal cancer.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2660656

Tumor-specific changes in mtDNA content in human cancer.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2660656

Increased mitochondrial DNA content in saliva associated with head and neck cancer

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2660656

Positive contribution of pathogenic mutations in the mitochondrial genome to the promotion of cancer by prevention from apoptosis

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2660656

Nuclear DNA but not mtDNA controls tumor phenotypes in mouse cells

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2660656

Mitochondrial DNA quantity increases with histopathologic grade in premalignant and malignant head and neck lesions

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2660656

Correlation between clinical characteristics and mitochondrial D-loop DNA mutations in hepatocellular carcinoma.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2660656

Decrease of mitochondrial DNA content and energy metabolism in renal cell carcinoma

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2660656

Alteration of the bioenergetic phenotype of mitochondria is a hallmark of breast, gastric, lung and oesophageal cancer.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2660656

Resistance of mitochondrial DNA-depleted cells against cell death: role of mitochondrial superoxide dismutase

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2660656

Detection of mitochondrial DNA mutations in the tumor and cerebrospinal fluid of medulloblastoma patients

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2660656

The bioenergetic signature of cancer: a marker of tumor progression.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2660656

Mitochondrial stress-induced calcium signaling, phenotypic changes and invasive behavior in human lung carcinoma A549 cells

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2660656

Low mitochondrial respiratory chain content correlates with tumor aggressiveness in renal cell carcinoma.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2660656

Accumulation of mitochondrial DNA deletions in human oral tissues -- effects of betel quid chewing and oral cancer.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2660656

Detection of mitochondrial DNA mutations in pancreatic cancer offers a "mass"-ive advantage over detection of nuclear DNA mutations.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2660656

Somatic mitochondrial DNA (mtDNA) mutations in papillary thyroid carcinomas and differential mtDNA sequence variants in cases with thyroid tumours

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2660656

Mutations in mitochondrial control region DNA in gastric tumours of Japanese patients.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2660656

Human skin mitochondrial DNA deletions associated with light exposure.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2660656

Somatic Mitochondrial DNA Mutations in Oral Cancer of Betel Quid Chewers

3 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.3390%2FIJMS10020674

Mitochondrial DNA mutation correlates with stage progression and prognosis in non-small cell lung cancer

21 January 2018

1 reference

12 December 2020

Somatic mitochondrial DNA mutations in primary and metastatic ovarian cancer

1 reference

12 December 2020

The prevalence of mtDNA4977 deletion in primary human endometrial carcinomas and matched control samples

1 reference

12 December 2020

High incidence of somatic mitochondrial DNA mutations in human ovarian carcinomas

1 reference

12 December 2020

Microsatellite instability, mitochondrial DNA large deletions, and mitochondrial DNA mutations in gastric carcinoma

1 reference

12 December 2020

Detection of mitochondrial DNA mutations in primary breast cancer and fine-needle aspirates

1 reference

12 December 2020

Mitochondrial D-loop mutations as clonal markers in multicentric hepatocellular carcinoma and plasma

1 reference

12 December 2020

Comprehensive scanning of somatic mitochondrial DNA mutations in breast cancer

1 reference

12 December 2020

Mutations in the mitochondrial DNA D-Loop region occur frequently in adenocarcinoma in Barrett's esophagus

1 reference

12 December 2020

Detection of mitochondrial DNA alterations in the serum of hepatocellular carcinoma patients

1 reference

12 December 2020

Somatic mitochondrial DNA mutations in neurofibromatosis type 1-associated tumors

1 reference

12 December 2020

Hexokinase receptor complex in hepatoma mitochondria: evidence from N,N'-dicyclohexylcarbodiimide-labeling studies for the involvement of the pore-forming protein VDAC

1 reference

12 December 2020

A tandem duplication in the D-loop of human mitochondrial DNA is associated with deletions in mitochondrial myopathies

1 reference

12 December 2020

Analysis of nuclear and mitochondrial DNA alterations in thyroid and renal oncocytic tumors

1 reference

12 December 2020

Ageing-associated tandem duplications in the D-loop of mitochondrial DNA of human muscle

1 reference

12 December 2020

High levels of mitochondrial DNA with an unstable 260-bp duplication in a patient with a mitochondrial myopathy

1 reference

12 December 2020

The frequency of 4977 base pair deletion of mitochondrial DNA in various types of liver disease and in normal liver

1 reference

12 December 2020

Tandem duplications and large-scale deletions of mitochondrial DNA are early molecular events of human aging process

1 reference

12 December 2020

Coordinate expression of nuclear and mitochondrial genes involved in energy production in carcinoma and oncocytoma

1 reference

12 December 2020

Novel mitochondrial DNA deletion found in a renal cell carcinoma

1 reference

12 December 2020

Detection of somatic mutations in the mitochondrial DNA control region of colorectal and gastric tumors by heteroduplex and single-strand conformation analysis

1 reference

12 December 2020

Mitochondrial DNA 4977 BP deletion mutations in lung carcinoma

1 reference

12 December 2020

Somatic mitochondrial DNA mutations in human chromophobe renal cell carcinomas

1 reference

12 December 2020

Large deletions in mitochondrial DNA in radiation-associated human thyroid tumors

1 reference

12 December 2020

Co-existence of high levels of a cytochrome b mutation and of a tandem 200 bp duplication in the D-loop of muscle human mitochondrial DNA

1 reference

12 December 2020

Increased sensitivity to cis-diamminedichloroplatinum induced apoptosis with mitochondrial DNA depletion

1 reference

12 December 2020

Human livers with cirrhosis and hepatocellular carcinoma have less mitochondrial DNA deletion than normal human livers.

1 reference

12 December 2020

Mitochondrial genome instability and mtDNA depletion in human cancers

1 reference

12 December 2020

Reduced mitochondrial DNA copy number is correlated with tumor progression and prognosis in Chinese breast cancer patients

1 reference

12 December 2020

Relationship between mitochondrial DNA mutations and clinical characteristics in human lung cancer

1 reference

12 December 2020

Deregulation of glucose transporter 1 and glycolytic gene expression by c-Myc

1 reference

12 December 2020

Mitochondrial DNA alteration in esophageal cancer

1 reference

12 December 2020

Identifiers

DOI

10.3390/IJMS10020674

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19333428%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19333428%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

PubMed publication ID

19333428

1 reference