The Wnt antagonist, Dickkopf-1, as a target for the treatment of neurodegenerative disorders. (Q37144218)

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6 January 2020

review article

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title

The Wnt antagonist, Dickkopf-1, as a target for the treatment of neurodegenerative disorders (English)

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6 January 2020

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2

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6 January 2020

Francesca Biagioni

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Federica Mastroiacovo

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6 January 2020

Giuseppe Battaglia

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Valeria Maria Gloria Bruno

6 January 2020

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6 January 2020

Ferdinando Nicoletti

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6 January 2020

author name string

Filippo Caraci

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6 January 2020

Irene Cappuccio

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6 January 2020

Andrea Caricasole

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Agata Copani

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6 January 2020

Eleonora Aronica

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publication date

22 April 2008

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6 January 2020

published in

Neurochemical Research

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volume

33

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issue

12

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6 January 2020

page(s)

2401-2406

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https://scigraph.springernature.com/pub.10.1007/s11064-008-9710-0

6 January 2020

exact match

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Dickkopf-1 is a member of a new family of secreted proteins and functions in head induction

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Lithium and risk for Alzheimer's disease in elderly patients with bipolar disorder

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Induction of the Wnt inhibitor, Dickkopf-1, is associated with neurodegeneration related to temporal lobe epilepsy.

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Functional and structural diversity of the human Dickkopf gene family

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Metabotropic glutamate receptor subtypes as targets for neuroprotective drugs

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Inhibition of Wnt signaling, modulation of Tau phosphorylation and induction of neuronal cell death by DKK1.

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12 December 2020

Memory impairment in now abstinent MDMA users and continued users: a longitudinal follow-up

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12 December 2020

Wnt signalling: antagonistic Dickkopfs

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Presenilin 1 associates with glycogen synthase kinase-3beta and its substrate tau

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Dickkopf-1, an inhibitor of the Wnt signaling pathway, is induced by p53.

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beta-catenin is a target for the ubiquitin-proteasome pathway

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Characterisation of the Wnt antagonists and their response to conditionally activated Wnt signalling in the developing mouse forebrain

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Kremen2 modulates Dickkopf2 activity during Wnt/LRP6 signaling

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Calcium and excitotoxic neuronal injury.

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Mitotic signaling by beta-amyloid causes neuronal death

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12 December 2020

Induction of Dickkopf-1, a negative modulator of the Wnt pathway, is associated with neuronal degeneration in Alzheimer's brain

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12 December 2020

Induction of Dickkopf-1, a negative modulator of the Wnt pathway, is required for the development of ischemic neuronal death.

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12 December 2020

Activation of Wnt signaling rescues neurodegeneration and behavioral impairments induced by beta-amyloid fibrils

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12 December 2020

Function and biological roles of the Dickkopf family of Wnt modulators

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Depolarization drives beta-Catenin into neuronal spines promoting changes in synaptic structure and function

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Presenilin couples the paired phosphorylation of beta-catenin independent of axin: implications for beta-catenin activation in tumorigenesis

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12 December 2020

Pathways by which Abeta facilitates tau pathology

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12 December 2020

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12 December 2020

10.1007/S11064-008-9710-0

Identifiers

DOI

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18427981%20AND%20SRC:MED&resulttype=core&format=json

6 January 2020

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