PPARdelta is pro-tumorigenic in a mouse model of COX-2-induced mammary cancer. (Q37144609)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19101649%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

title

PPARdelta is pro-tumorigenic in a mouse model of COX-2-induced mammary cancer (English)

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18 January 2020

1

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18 January 2020

Jeffrey Peters

5

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18 January 2020

Timothy Hla

6

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18 January 2020

author name string

Youxi Ai

2

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18 January 2020

Kirsi Narko

3

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18 January 2020

Zhenglong Wang

4

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18 January 2020

publication date

24 December 2008

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Prostaglandins and Other Lipid Mediators

18 January 2020

published in

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18 January 2020

volume

88

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18 January 2020

issue

3-4

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18 January 2020

page(s)

97-100

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COX-2 suppresses tissue factor expression via endocannabinoid-directed PPARdelta activation

18 January 2020

cites work

1 reference

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Inflammation and breast cancer. Cyclooxygenase/prostaglandin signaling and breast cancer

6 September 2017

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The toxicology of ligands for peroxisome proliferator-activated receptors (PPAR).

6 September 2017

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The role of peroxisome proliferator-activated receptor-beta/delta in epithelial cell growth and differentiation

6 September 2017

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The prostaglandin E2 receptor EP2 is required for cyclooxygenase 2-mediated mammary hyperplasia

6 September 2017

1 reference

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PPARdelta status and Apc-mediated tumourigenesis in the mouse intestine

6 September 2017

1 reference

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Activation of nuclear hormone receptor peroxisome proliferator-activated receptor-delta accelerates intestinal adenoma growth

6 September 2017

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Role of prostaglandin E2-dependent angiogenic switch in cyclooxygenase 2-induced breast cancer progression

6 September 2017

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Cyclooxygenase-2 modulates cellular growth and promotes tumorigenesis.

6 September 2017

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Prostacyclin-mediated activation of peroxisome proliferator-activated receptor delta in colorectal cancer

6 September 2017

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Growth, adipose, brain, and skin alterations resulting from targeted disruption of the mouse peroxisome proliferator-activated receptor beta(delta)

6 September 2017

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COX-2 inhibitors. A new class of antiangiogenic agents

6 September 2017

1 reference

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PPARdelta is an APC-regulated target of nonsteroidal anti-inflammatory drugs

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2662999

Cyclo-oxygenase-2-derived prostacyclin mediates embryo implantation in the mouse via PPARdelta

6 September 2017

1 reference

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Suppression of intestinal polyposis in Apc delta716 knockout mice by inhibition of cyclooxygenase 2 (COX-2)

6 September 2017

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Peroxisome proliferator-activated receptor-beta/delta (PPARbeta/delta) ligands do not potentiate growth of human cancer cell lines

6 September 2017

1 reference

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COX-2 inhibitor celecoxib suppresses tumor growth and lung metastasis of a murine mammary cancer.

14 September 2017

1 reference

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Isoform specific changes in PPAR alpha and beta in colon and breast cancer with differentiation

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2662999

Activation of peroxisome proliferator-activated receptor delta stimulates the proliferation of human breast and prostate cancer cell lines.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2662999

Cyclooxygenase-2 overexpression and tumor formation are blocked by sulindac in a murine model of familial adenomatous polyposis.

14 September 2017

1 reference

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Ligand activation of peroxisome proliferator-activated receptor-beta/delta (PPARbeta/delta) and inhibition of cyclooxygenase 2 (COX2) attenuate colon carcinogenesis through independent signaling mechanisms.

27 June 2018

1 reference

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Growth of transgenic RAF-induced lung adenomas is increased in mice with a disrupted PPARbeta/delta gene.

3 September 2018

1 reference

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Ligand activation of peroxisome proliferator-activated receptor beta inhibits colon carcinogenesis.

3 September 2018

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Peroxisome proliferator-activated receptor-delta attenuates colon carcinogenesis.

3 September 2018

1 reference

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Peroxisome proliferator-activated receptor beta (delta)-dependent regulation of ubiquitin C expression contributes to attenuation of skin carcinogenesis.

3 September 2018

1 reference

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Cyclooxygenase-2 promotes prostate cancer progression

3 September 2018

1 reference

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Overexpression of cyclooxygenase-2 is sufficient to induce tumorigenesis in transgenic mice

3 September 2018

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12 December 2020

Prognostic significance of elevated cyclooxygenase-2 expression in breast cancer

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12 December 2020

Cyclooxygenase-2 expression in fibroblasts and endothelial cells of intestinal polyps

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12 December 2020

Overexpression of cyclooxygenase-2 in carcinoma of the pancreas

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12 December 2020

Overexpression of cyclooxygenase-2 in squamous cell carcinoma of the urinary bladder

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12 December 2020

10.1016/J.PROSTAGLANDINS.2008.11.004

Identifiers

DOI

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18 January 2020

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18 January 2020

1 reference