Interplay of alpha-synuclein binding and conformational switching probed by single-molecule fluorescence. (Q37153744)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19293380%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

title

Interplay of alpha-synuclein binding and conformational switching probed by single-molecule fluorescence (English)

1 reference

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23 January 2020

1 reference

3

1 reference

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23 January 2020

author name string

Allan Chris M Ferreon

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19293380%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

Yann Gambin

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19293380%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

Ashok A Deniz

series ordinal

4

1 reference

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23 January 2020

language of work or name

English

0 references

publication date

17 March 2009

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19293380%20AND%20SRC:MED&resulttype=core&format=json

Proceedings of the National Academy of Sciences of the United States of America

23 January 2020

published in

1 reference

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23 January 2020

volume

106

1 reference

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23 January 2020

issue

14

1 reference

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23 January 2020

page(s)

5645-5650

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19293380%20AND%20SRC:MED&resulttype=core&format=json

The protein folding problem

23 January 2020

cites work

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6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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Alpha-synuclein blocks ER-Golgi traffic and Rab1 rescues neuron loss in Parkinson's models

6 September 2017

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6 September 2017

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Quantification of alpha-synuclein binding to lipid vesicles using fluorescence correlation spectroscopy

6 September 2017

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Alpha-synuclein cooperates with CSPalpha in preventing neurodegeneration

6 September 2017

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Accurate FRET measurements within single diffusing biomolecules using alternating-laser excitation

6 September 2017

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Structure and dynamics of micelle-bound human alpha-synuclein

6 September 2017

1 reference

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Alpha-synuclein structures from fluorescence energy-transfer kinetics: implications for the role of the protein in Parkinson's disease

6 September 2017

1 reference

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Structure of membrane-bound alpha-synuclein studied by site-directed spin labeling

6 September 2017

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Theory of protein folding

6 September 2017

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A broken alpha -helix in folded alpha -Synuclein

6 September 2017

1 reference

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Synaptic vesicle depletion correlates with attenuated synaptic responses to prolonged repetitive stimulation in mice lacking alpha-synuclein

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2667048

alpha-Synuclein occurs in lipid-rich high molecular weight complexes, binds fatty acids, and shows homology to the fatty acid-binding proteins

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2667048

Why are "natively unfolded" proteins unstructured under physiologic conditions?

6 September 2017

1 reference

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Synucleins are developmentally expressed, and alpha-synuclein regulates the size of the presynaptic vesicular pool in primary hippocampal neurons

6 September 2017

1 reference

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Mice lacking alpha-synuclein display functional deficits in the nigrostriatal dopamine system

6 September 2017

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Intrinsically unstructured proteins: re-assessing the protein structure-function paradigm

6 September 2017

1 reference

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Single-pair fluorescence resonance energy transfer on freely diffusing molecules: observation of Förster distance dependence and subpopulations

6 September 2017

1 reference

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Stabilization of alpha-synuclein secondary structure upon binding to synthetic membranes

6 September 2017

1 reference

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Ala30Pro mutation in the gene encoding alpha-synuclein in Parkinson's disease

6 September 2017

1 reference

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Alpha-synuclein in Lewy bodies

6 September 2017

1 reference

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Mutation in the alpha-synuclein gene identified in families with Parkinson's disease

6 September 2017

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NACP, a protein implicated in Alzheimer's disease and learning, is natively unfolded

6 September 2017

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Molecular cloning of cDNA encoding an unrecognized component of amyloid in Alzheimer disease

6 September 2017

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Identification of two distinct synucleins from human brain

6 September 2017

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Characterization of a novel protein regulated during the critical period for song learning in the zebra finch.

6 September 2017

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Binding of dodecyl sulfate to proteins at high binding ratios. Possible implications for the state of proteins in biological membranes

6 September 2017

1 reference

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Synuclein: a neuron-specific protein localized to the nucleus and presynaptic nerve terminal

6 September 2017

1 reference

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Protein unfolding in detergents: effect of micelle structure, ionic strength, pH, and temperature

6 September 2017

1 reference

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Navigating the folding routes

14 September 2017

1 reference

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Protein phase diagrams II: nonideal behavior of biochemical reactions in the presence of osmolytes

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2667048

Interaction of human alpha-Synuclein and Parkinson's disease variants with phospholipids. Structural analysis using site-directed mutagenesis.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2667048

27 June 2018

Properties of detergents

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2667048

Membrane-bound alpha-synuclein forms an extended helix: long-distance pulsed ESR measurements using vesicles, bicelles, and rodlike micelles

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2667048

Broken helix in vesicle and micelle-bound alpha-synuclein: insights from site-directed spin labeling-EPR experiments and MD simulations.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2667048

Alpha-synuclein multistate folding thermodynamics: implications for protein misfolding and aggregation

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2667048

Thermodynamics of denaturant-induced unfolding of a protein that exhibits variable two-state denaturation

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2667048

Effects of Parkinson's disease-linked mutations on the structure of lipid-associated alpha-synuclein

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2667048

A structural and functional role for 11-mer repeats in alpha-synuclein and other exchangeable lipid binding proteins

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2667048

Binding of alpha-synuclein to brain vesicles is abolished by familial Parkinson's disease mutation.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2667048

Mapping Long-Range Interactions in α-Synuclein using Spin-Label NMR and Ensemble Molecular Dynamics Simulations

3 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.0809232106

Measuring conformational dynamics: a new FCS-FRET approach

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19293380

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

alpha-Synuclein membrane interactions and lipid specificity

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19293380

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Antiparallel arrangement of the helices of vesicle-bound alpha-synuclein

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19293380

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.0809232106

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19293380%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19293380%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

PubMed publication ID

19293380

1 reference