Defining targets for investigating the pharmacogenomics of adverse drug reactions to antifungal agents (Q37157893)

18 August 2017

1 reference

title

Defining targets for investigating the pharmacogenomics of adverse drug reactions to antifungal agents (English)

1 reference

18 August 2017

1 reference

2

Stephen Chanock

1 reference

18 August 2017

Joseph Meletiadis

1

1 reference

18 August 2017

Thomas J Walsh

series ordinal

3

1 reference

18 August 2017

publication date

1 May 2008

1 reference

18 August 2017

1 reference

18 August 2017

volume

9

1 reference

18 August 2017

issue

5

1 reference

18 August 2017

page(s)

561-584

1 reference

Incidence of adverse drug reactions in hospitalized patients: a meta-analysis of prospective studies

18 August 2017

cites work

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.5.561

Pharmacogenetics: an opportunity for a safer and more efficient pharmacotherapy

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.5.561

Genomics and the prediction of xenobiotic toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.5.561

Toxicogenetics in drug development

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.5.561

Pharmacogenetics and adverse drug reactions

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.5.561

Implications of cytochrome P450 genetic polymorphisms on the toxicity of antitumor agents

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.5.561

Mercaptopurine therapy intolerance and heterozygosity at the thiopurine S-methyltransferase gene locus

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.5.561

Adverse drug reactions: role of pharmacogenomics

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.5.561

Association between presence of HLA-B*5701, HLA-DR7, and HLA-DQ3 and hypersensitivity to HIV-1 reverse-transcriptase inhibitor abacavir

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.5.561

TNF-alpha promoter region gene polymorphisms in HIV-positive patients with lipodystrophy

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.5.561

The association of atopy with a gain-of-function mutation in the alpha subunit of the interleukin-4 receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.5.561

Timing of new black box warnings and withdrawals for prescription medications

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.5.561

Human pharmacogenomic variations and their implications for antifungal efficacy

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.5.561

Liposomal amphotericin B for empirical therapy in patients with persistent fever and neutropenia. National Institute of Allergy and Infectious Diseases Mycoses Study Group

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.5.561

Evolving role of flucytosine in immunocompromised patients: new insights into safety, pharmacokinetics, and antifungal therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.5.561

Itraconazole oral solution and intravenous formulations: a review of pharmacokinetics and pharmacodynamics

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.5.561

Congestive heart failure associated with itraconazole

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.5.561

Fluconazole. An update of its pharmacodynamic and pharmacokinetic properties and therapeutic use in major superficial and systemic mycoses in immunocompromised patients

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.5.561

Alopecia associated with fluconazole therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.5.561

Voriconazole: a new triazole antifungal agent

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.5.561

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.5.561

Safety and tolerability of caspofungin acetate in the treatment of fungal infections

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.5.561

Caspofungin: pharmacology, safety and therapeutic potential in superficial and invasive fungal infections

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.5.561

The complexities of hepatic drug transport: current knowledge and emerging concepts.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.5.561

The epidemiology of nephrotoxicity associated with conventional amphotericin B therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.5.561

Potential mechanisms by which Peceol increases the gastrointestinal absorption of amphotericin B.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.5.561

Genetic polymorphisms of drug transporters: pharmacokinetic and pharmacodynamic consequences in pharmacotherapy

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.5.561

Role of pharmacogenetics of ATP-binding cassette transporters in the pharmacokinetics of drugs.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.5.561

Use of amphotericin B as optical probe to study conformational changes and thermodynamic stability in human serum albumin

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.5.561

Human alpha-1-glycoprotein and its interactions with drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.5.561

Influence of the ORM1 phenotypes on serum unbound concentration and protein binding of quinidine

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.5.561

High-affinity binding of warfarin, salicylate and diazepam to natural mutants of human serum albumin modified in the C-terminal end

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.5.561

Role of plasma lipids and lipoproteins in predicting amphotericin B-induced nephrotoxicity in pediatric oncology patients

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.5.561

Role of plasma lipoproteins in modifying the biological activity of hydrophobic drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.5.561

Influence of diet on experimental toxicity of amphotericin B deoxycholate

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.5.561

Preferential distribution of amphotericin B lipid complex into human HDL3 is a consequence of high density lipoprotein coat lipid content

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.5.561

The endocytic process in CHO cells, a toxic pathway of the polyene antibiotic amphotericin B.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.5.561

The use of amphotericin B to detect inhibitors of cellular cholesterol biosynthesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.5.561

Influence of lipoproteins on renal cytotoxicity and antifungal activity of amphotericin B.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.5.561

Lipoprotein transport in the metabolic syndrome: methodological aspects of stable isotope kinetic studies.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.5.561

Cholesteryl ester transfer protein facilitates the movement of water-insoluble drugs between lipoproteins: a novel biological function for a well-characterized lipid transfer protein

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.5.561

Amphotericin B-induced nephrotoxicity: a review

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.5.561

Renal transport of antibiotics and nephrotoxicity: a review

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.5.561

Amphotericin B: current understanding of mechanisms of action

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.5.561

The effect of thromboxane A2 receptor antagonism on amphotericin B-induced renal vasoconstriction in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.5.561

Release of prostaglandin E-2 in bovine brain endothelial cells after exposure to three unique forms of the antifungal drug amphotericin-B: role of COX-2 in amphotericin-B induced fever

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.5.561

Protective effect of the G-765C COX-2 polymorphism on subclinical atherosclerosis and inflammatory markers in asymptomatic subjects with cardiovascular risk factors.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.5.561

Differential expression of genes encoding immunomodulatory proteins in response to amphotericin B in human mononuclear cells identified by cDNA microarray analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.5.561

Amphotericin B induces expression of genes encoding chemokines and cell adhesion molecules in the human monocytic cell line THP-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.5.561

Differential expression of cytokines and chemokines in human monocytes induced by lipid formulations of amphotericin B

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.5.561

The antifungal drug amphotericin B promotes inflammatory cytokine release by a Toll-like receptor- and CD14-dependent mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.5.561

Secretion of proinflammatory cytokines and chemokines during amphotericin B exposure is mediated by coactivation of toll-like receptors 1 and 2.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.5.561

Analysis of amphotericin B-induced cell signaling with chemical inhibitors of signaling molecules

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.5.561

CD14 and toll-like receptors: potential contribution of genetic factors and mechanisms to inflammation and allergy

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.5.561

The role of Toll-like receptors in immune disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.5.561

The association of cytokine gene polymorphisms with febrile non-hemolytic transfusion reaction in multitransfused patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.5.561

Increased frequency of interleukin-1beta (-511) allele 2 in febrile seizures

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.5.561

Differential effects of amphotericin B and liposomal amphotericin B on inflammatory cells in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.5.561

Effects of amphotericin B and caspofungin on histamine expression

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.5.561

Investigation of the potential relationships between plasma voriconazole concentrations and visual adverse events or liver function test abnormalities

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.5.561

Pharmacokinetics of voriconazole and cytochrome P450 2C19 genetic status

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.5.561

No clinically significant effect of erythromycin or azithromycin on the pharmacokinetics of voriconazole in healthy male volunteers

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.5.561

Opposite effects of short-term and long-term St John's wort intake on voriconazole pharmacokinetics

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.5.561

The AmpliChip CYP450 genotyping test: Integrating a new clinical tool

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.5.561

Vertebrate photoreceptors

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.5.561

Digoxin retinal toxicity. Clinical and electrophysiological evaluation of a cone dysfunction syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.5.561

Drug delivery to the retina: challenges and opportunities

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.5.561

Determination of vitreous, aqueous, and plasma concentration of orally administered voriconazole in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.5.561

Expression of multidrug resistance-associated protein (MRP) in human retinal pigment epithelial cells and its interaction with BAPSG, a novel aldose reductase inhibitor

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.5.561

Drug transport in corneal epithelium and blood-retina barrier: emerging role of transporters in ocular pharmacokinetics

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.5.561

New therapies with potential neuro-ophthalmologic toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.5.561

Viagra (sildenafil citrate) and ophthalmology

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.5.561

Acquired colour vision deficiency in patients receiving digoxin maintenance therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.5.561

Direct interaction of antifungal azole-derivatives with calmodulin: a possible mechanism for their therapeutic activity

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.5.561

Anti-mycotics suppress interleukin-4 and interleukin-5 production in anti-CD3 plus anti-CD28-stimulated T cells from patients with atopic dermatitis

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.5.561

Nitroimidazole derivatives inhibit anterior pituitary cell function apparently by a direct effect on the catalytic subunit of the adenylate cyclase holoenzyme

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.5.561

Antifungal activity in Saccharomyces cerevisiae is modulated by calcium signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.5.561

Calcineurin A of Candida albicans: involvement in antifungal tolerance, cell morphogenesis and virulence

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.5.561

Systemically administered antifungal agents. A review of their clinical pharmacology and therapeutic applications

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.5.561

Pharmacology and toxicity of high-dose ketoconazole

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.5.561

Pharmacokinetic and pharmacodynamic studies of the effect of ketoconazole on reproductive function in male rats

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.5.561

Multidrug resistance genes and p-glycoprotein in the testis of the rat, mouse, Guinea pig, and human

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.5.561

Mammalian drug efflux transporters of the ATP binding cassette (ABC) family: an overview.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.5.561

Interaction of common azole antifungals with P glycoprotein

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.5.561

Interrelationship between substrates and inhibitors of human CYP3A and P-glycoprotein.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.5.561

Ketoconazole-associated hepatic injury. A clinicopathological study of 55 cases

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.5.561

Hepatotoxicity of ketoconazole in Sprague-Dawley rats: glutathione depletion, flavin-containing monooxygenases-mediated bioactivation and hepatic covalent binding

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.5.561

A family of drug transporters: the multidrug resistance-associated proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.5.561

Human flavin-containing monooxygenase (form 3): polymorphisms and variations in chemical metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.5.561

Genetic variability at the human FMO1 locus: significance of a basal promoter yin yang 1 element polymorphism (FMO1*6)

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.5.561

Pharmacogenetics of the major polymorphic metabolizing enzymes.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.5.561

Single nucleotide polymorphisms in multidrug resistance associated protein 2 (MRP2/ABCC2): its impact on drug disposition

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.5.561

Hepatotoxicity related to itraconazole: report of three cases

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.5.561

Fatal acute hepatic necrosis due to dose-dependent fluconazole hepatotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.5.561

Terbinafine-induced cholestatic liver disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.5.561

Identification of a reactive metabolite of terbinafine: insights into terbinafine-induced hepatotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.5.561

Flucytosine: a review of its pharmacology, clinical indications, pharmacokinetics, toxicity and drug interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.5.561

An in vitro study on the active conversion of flucytosine to fluorouracil by microorganisms in the human intestinal microflora.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.5.561

5-fluorocytosine-related bone-marrow depression and conversion to fluorouracil: a pilot study

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.5.561

Limited oral bioavailability and active epithelial excretion of paclitaxel (Taxol) caused by P-glycoprotein in the intestine

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.5.561

Substantial excretion of digoxin via the intestinal mucosa and prevention of long-term digoxin accumulation in the brain by the mdr 1a P-glycoprotein

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.5.561

MRP8, ATP-binding cassette C11 (ABCC11), is a cyclic nucleotide efflux pump and a resistance factor for fluoropyrimidines 2',3'-dideoxycytidine and 9'-(2'-phosphonylmethoxyethyl)adenine

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.5.561

The multidrug resistance protein 5 functions as an ATP-dependent export pump for cyclic nucleotides

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.5.561

Role of MRP4 and MRP5 in biology and chemotherapy

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.5.561

Flucytosine: correlation between toxicity and pharmacokinetic parameters.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.5.561

The concentrative nucleoside transporter family, SLC28

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.5.561

Thymidylate synthase mRNA level in adenocarcinoma of the stomach: a predictor for primary tumor response and overall survival

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.5.561

ERCC1 mRNA levels complement thymidylate synthase mRNA levels in predicting response and survival for gastric cancer patients receiving combination cisplatin and fluorouracil chemotherapy

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.5.561

Comparison of caspofungin and amphotericin B for invasive candidiasis

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.5.561

Safety and pharmacokinetics of intravenous anidulafungin in children with neutropenia at high risk for invasive fungal infections

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.5.561

Immunologically mediated signaling in basophils and mast cells: finding therapeutic targets for allergic diseases in the human FcvarepsilonR1 signaling pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.5.561

Clinical relevance of Fc gamma receptor polymorphisms

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.5.561

Pathophysiology of urticaria.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.5.561

Peptidergic pathway in human skin and rat peritoneal mast cell activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.5.561

Azole fungicides affect mammalian steroidogenesis by inhibiting sterol 14 alpha-demethylase and aromatase

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.5.561

Systemic antifungal agents. Drug interactions of clinical significance

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.5.561

Pharmacokinetic aspects of treating infections in the intensive care unit: focus on drug interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.5.561

Effects of the antifungal agents on oxidative drug metabolism: clinical relevance

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.5.561

The interaction of representative members from two classes of antimycotics--the azoles and the allylamines--with cytochromes P-450 in steroidogenic tissues and liver

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.5.561

Drug interactions during therapy with three major groups of antimicrobial agents

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.5.561

Factors influencing the magnitude and clinical significance of drug interactions between azole antifungals and select immunosuppressants.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.5.561

Effect of antifungal drugs on cytochrome P450 (CYP) 1A2, CYP2D6, and CYP2E1 activities in human liver microsomes

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.5.561

Effect of antifungal drugs on cytochrome P450 (CYP) 2C9, CYP2C19, and CYP3A4 activities in human liver microsomes

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.5.561

Involvement of organic cation transporter 1 in hepatic and intestinal distribution of metformin

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.5.561

Substrate selectivity of human cytochrome P450 2C9: importance of residues 476, 365, and 114 in recognition of diclofenac and sulfaphenazole and in mechanism-based inactivation by tienilic acid

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.5.561

Mammalian microsomal cytochrome P450 monooxygenase: structural adaptations for membrane binding and functional diversity

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.5.561

Ketoconazole-induced conformational changes in the active site of cytochrome P450eryF

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.5.561

The amino acid residues affecting the activity and azole susceptibility of rat CYP51 (sterol 14-demethylase P450).

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.5.561

Comparative evaluation of the safety and efficacy of HMG-CoA reductase inhibitor monotherapy in the treatment of primary hypercholesterolemia

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.5.561

Structure-activity relationship: analyses of p-glycoprotein substrates and inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.5.561

Genetic polymorphisms of the human MDR1 drug transporter

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.5.561

Pattern-recognition techniques with haplotype analysis in pharmacogenomics

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.5.561

A haplotype map of the human genome

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.5.561

Replicating genotype-phenotype associations

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.5.561

Scanning the horizon: what is the future of genome-wide association studies in accelerating discoveries in cancer etiology and prevention?

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.5.561

Genome-wide association study identifies novel breast cancer susceptibility loci

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.5.561

A genome-wide association study identifies alleles in FGFR2 associated with risk of sporadic postmenopausal breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.5.561

Common variants on chromosomes 2q35 and 16q12 confer susceptibility to estrogen receptor-positive breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.5.561

Genome-wide association scan identifies a colorectal cancer susceptibility locus on chromosome 8q24.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.5.561

Genome-wide association study identifies a second prostate cancer susceptibility variant at 8q24.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.5.561

Genome-wide association study of prostate cancer identifies a second risk locus at 8q24

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.5.561

A common variant on chromosome 9p21 affects the risk of myocardial infarction

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.5.561

A common allele on chromosome 9 associated with coronary heart disease

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.5.561

Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.5.561

A genome-wide association study of type 2 diabetes in Finns detects multiple susceptibility variants

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.5.561

Robust associations of four new chromosome regions from genome-wide analyses of type 1 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.5.561

Replication of genome-wide association signals in UK samples reveals risk loci for type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.5.561

Sequence variants in the autophagy gene IRGM and multiple other replicating loci contribute to Crohn's disease susceptibility

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.5.561

A common genetic risk factor for colorectal and prostate cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.5.561

Multiple regions within 8q24 independently affect risk for prostate cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.5.561

Can personalized drug therapy be achieved? A closer look at pharmaco-metabonomics

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.5.561

21 January 2018

When good drugs go bad.

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.5.561

Potent cytochrome P450 2C19 genotype–related interaction between voriconazole and the cytochrome P450 3A4 inhibitor ritonavir

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.5.561

Role of Drug Disposition in Drug Hypersensitivity: A Chemical, Molecular, and Clinical Perspective

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.5.561

A genome-wide association scan of tag SNPs identifies a susceptibility variant for colorectal cancer at 8q24.21

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.5.561

Cytochrome P450 polymorphisms are associated with reduced warfarin dose

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.5.561

Identification of Residues within the Drug-binding Domain of the Human Multidrug Resistance P-glycoprotein by Cysteine-scanning Mutagenesis and Reaction with Dibromobimane

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.5.561

21 January 2018

Identifiers

DOI

10.2217/14622416.9.5.561

1 reference

18 August 2017

1 reference