Pro370Leu mutant myocilin impairs mitochondrial functions in human trabecular meshwork cells. (Q37166653)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19390644%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

title

Pro370Leu mutant myocilin impairs mitochondrial functions in human trabecular meshwork cells (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19390644%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

1 reference

Yuan He

1

1 reference

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26 January 2020

Kar Wah Leung

series ordinal

2

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26 January 2020

Ye-Hong Zhuo

series ordinal

3

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26 January 2020

Jian Ge

series ordinal

4

1 reference

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26 January 2020

publication date

23 April 2009

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26 January 2020

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26 January 2020

volume

15

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26 January 2020

page(s)

815-825

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Pro370Leu MYOC gene mutation in a large Chinese family with juvenile-onset open angle glaucoma: correlation between genotype and phenotype.

26 January 2020

cites work

1 reference

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Mitochondrial defects and dysfunction in calcium regulation in glaucomatous trabecular meshwork cells

6 September 2017

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In and Out of the ER: Protein Folding, Quality Control, Degradation, and Related Human Diseases

6 September 2017

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Mitochondrial association of myocilin, product of a glaucoma gene, in human trabecular meshwork cells

6 September 2017

1 reference

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Pro370Leu mutant myocilin disturbs the endoplasm reticulum stress response and mitochondrial membrane potential in human trabecular meshwork cells.

6 September 2017

1 reference

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Glaucomatous outflow pathway and oxidative stress.

6 September 2017

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Role of mitochondrial oxidative stress to explain the different longevity between genders: protective effect of estrogens

6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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Mitochondrial import and the twin-pore translocase

6 September 2017

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FAST is a BCL-X(L)-associated mitochondrial protein

6 September 2017

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Mmm2p, a mitochondrial outer membrane protein required for yeast mitochondrial shape and maintenance of mtDNA nucleoids.

6 September 2017

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The protein import machinery of mitochondria

6 September 2017

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Genetic dissection of myocilin glaucoma

6 September 2017

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Evaluation of optineurin sequence variations in 1,048 patients with open-angle glaucoma

6 September 2017

1 reference

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Constitutive protein secretion from the trans-Golgi network to the plasma membrane

6 September 2017

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The mystery of nonclassical protein secretion. A current view on cargo proteins and potential export routes

6 September 2017

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Mechanisms of protein import into mitochondria

6 September 2017

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Collaborative Initial Glaucoma Treatment Study: a summary of results to date

6 September 2017

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Common eye diseases of elderly people: identifying and treating causes of vision loss

6 September 2017

1 reference

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Myocilin and glaucoma: facts and ideas.

6 September 2017

1 reference

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Measuring mitochondrial reactive oxygen species.

6 September 2017

1 reference

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Glucocorticoid induction of the glaucoma gene MYOC in human and monkey trabecular meshwork cells and tissues

6 September 2017

1 reference

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Localization of myocilin to the golgi apparatus in Schlemm's canal cells

6 September 2017

1 reference

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The road taken: past and future foundations of membrane traffic

6 September 2017

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Vascular aspects in the pathophysiology of glaucomatous optic neuropathy.

6 September 2017

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Vascular dysregulation: a principal risk factor for glaucomatous damage?

6 September 2017

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6 September 2017

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6 September 2017

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Identification of a gene that causes primary open angle glaucoma.

6 September 2017

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Number of people with glaucoma worldwide

6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

Global data on blindness

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6 September 2017

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In vitro and in vivo study on the secretion of the Gly367Arg mutant myocilin protein.

6 September 2017

1 reference

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Combined modulation of the mitochondrial ATP-dependent potassium channel and the permeability transition pore causes prolongation of the biphasic calcium dynamics

14 September 2017

1 reference

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The apoptotic effect of brucine from the seed of Strychnos nux-vomica on human hepatoma cells is mediated via Bcl-2 and Ca2+ involved mitochondrial pathway

14 September 2017

1 reference

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Apoptosis driven by IP(3)-linked mitochondrial calcium signals

14 September 2017

1 reference

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GLC1A mutations point to regions of potential functional importance on the TIGR/MYOC protein.

27 June 2018

1 reference

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Proteins secreted by human trabecular cells. Glucocorticoid and other effects.

27 June 2018

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Mitochondrial complex I defect induces ROS release and degeneration in trabecular meshwork cells of POAG patients: protection by antioxidants

27 June 2018

1 reference

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Isolation, culture, and characterization of human fetal trabecular meshwork cells

3 September 2018

1 reference

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Dexamethasone inhibition of trabecular meshwork cell phagocytosis and its modulation by glucocorticoid receptor beta

3 September 2018

1 reference

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Genome-wide expression profile of human trabecular meshwork cultured cells, nonglaucomatous and primary open angle glaucoma tissue.

3 September 2018

1 reference

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A preliminary study on gene mutation and its function in a large family (GZ.1 pedigree) with open-angle glaucoma

3 September 2018

1 reference

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Oxidative DNA damage in the human trabecular meshwork: clinical correlation in patients with primary open-angle glaucoma.

3 September 2018

1 reference

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[Ca2+]i signaling between mitochondria and endoplasmic reticulum in neurons is regulated by microtubules. From mitochondrial permeability transition pore to Ca2+-induced Ca2+ release

3 September 2018

1 reference

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Evaluation and understanding of myocilin mutations in Indian primary open angle glaucoma patients.

3 September 2018

1 reference

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Distribution of myocilin, a glaucoma gene product, in human corneal fibroblasts

3 September 2018

1 reference

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Flow cytometric measurement of reactive oxygen species production by normal and thalassaemic red blood cells

3 September 2018

1 reference

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The Ocular Hypertension Treatment Study: baseline factors that predict the onset of primary open-angle glaucoma.

3 September 2018

1 reference

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Distribution of myocilin and extracellular matrix components in the juxtacanalicular tissue of human eyes.

3 September 2018

1 reference

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Gene transfer of dominant-negative RhoA increases outflow facility in perfused human anterior segment cultures.

3 September 2018

1 reference

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Gene mutation in patients with primary open-angle glaucoma in a pedigree in China.

3 September 2018

1 reference

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Genetic modification of human trabecular meshwork with lentiviral vectors

3 September 2018

1 reference

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Regulation of TIGR/MYOC gene expression in human trabecular meshwork cells

3 September 2018

1 reference

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mRNA in situ hybridization of TIGR/MYOC in human trabecular meshwork.

3 September 2018

1 reference

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Identification of the region in the N-terminal domain responsible for the cytoplasmic localization of Myoc/Tigr and its association with microtubules.

3 September 2018

1 reference

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Analysis of myocilin mutations in 1703 glaucoma patients from five different populations

3 September 2018

1 reference

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Localization of the stress proteins alpha B-crystallin and trabecular meshwork inducible glucocorticoid response protein in normal and glaucomatous trabecular meshwork.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2672150

Gene structure and properties of TIGR, an olfactomedin-related glycoprotein cloned from glucocorticoid-induced trabecular meshwork cells

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2672150

Recurrent mutations in a single exon encoding the evolutionarily conserved olfactomedin-homology domain of TIGR in familial open-angle glaucoma

3 September 2018

1 reference

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Protein import into mitochondria

3 September 2018

1 reference

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Distribution of Myocilin and Extracellular Matrix Components in the Corneoscleral Meshwork of Human Eyes

4 December 2018

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12 December 2020

Human trabecular meshwork cells in culture: morphology and extracellular matrix components

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12 December 2020

Cleavage-site motifs in mitochondrial targeting peptides

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12 December 2020

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12 December 2020

Mitochondrial modulation of Ca2+ -induced Ca2+ -release in rat sensory neurons

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12 December 2020

Ultrastructural localization of myocilin in human trabecular meshwork cells and tissues

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12 December 2020

The Advanced Glaucoma Intervention Study (AGIS): 7. The relationship between control of intraocular pressure and visual field deterioration.The AGIS Investigators

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12 December 2020

Expression of the glaucoma gene myocilin (MYOC) in the human optic nerve head

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12 December 2020

Myocilin is associated with mitochondria in human trabecular meshwork cells

1 reference

12 December 2020

Identifiers

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19390644%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

1 reference