A two-step binding model proposed for the electrostatic interactions of ricin a chain with ribosomes. (Q37180842)

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23 January 2020

title

A two-step binding model proposed for the electrostatic interactions of ricin a chain with ribosomes (English)

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23 January 2020

2

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23 January 2020

author name string

Xiao-Ping Li

1

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23 January 2020

Miguel Remacha

3

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23 January 2020

Juan P G Ballesta

4

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23 January 2020

Nilgun E Tumer

5

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language of work or name

English

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publication date

1 May 2009

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23 January 2020

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23 January 2020

volume

48

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23 January 2020

issue

18

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23 January 2020

page(s)

3853-3863

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The C-terminal fragment of the ribosomal P protein complexed to trichosanthin reveals the interaction between the ribosome-inactivating protein and the ribosome

23 January 2020

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The ribosomal stalk is required for ribosome binding, depurination of the rRNA and cytotoxicity of ricin A chain in Saccharomyces cerevisiae

6 September 2017

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The electrostatic character of the ribosomal surface enables extraordinarily rapid target location by ribotoxins

6 September 2017

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Structures of the bacterial ribosome at 3.5 A resolution

6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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Trichosanthin interacts with acidic ribosomal proteins P0 and P1 and mitotic checkpoint protein MAD2B

6 September 2017

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The two faces of the Escherichia coli 23 S rRNA sarcin/ricin domain: the structure at 1.11 A resolution

6 September 2017

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6 September 2017

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X-ray structure of recombinant ricin A-chain at 1.8 A resolution

6 September 2017

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Mechanism of action of the toxic lectins abrin and ricin

6 September 2017

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Different biological properties of the two constituent peptide chains of ricin a toxic protein inhibiting protein synthesis

6 September 2017

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The cytotoxins alpha-sarcin and ricin retain their specificity when tested on a synthetic oligoribonucleotide (35-mer) that mimics a region of 28 S ribosomal ribonucleic acid.

6 September 2017

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The RNA N-glycosidase activity of ricin A-chain. The characteristics of the enzymatic activity of ricin A-chain with ribosomes and with rRNA.

6 September 2017

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Interaction of elongation factors EF-G and EF-Tu with a conserved loop in 23S RNA.

6 September 2017

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Crystallographic refinement of ricin to 2.5 A

6 September 2017

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Stable binding of the eukaryotic acidic phosphoproteins to the ribosome is not an absolute requirement for in vivo protein synthesis

6 September 2017

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Ribotoxin recognition of ribosomal RNA and a proposal for the mechanism of translocation

6 September 2017

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Ribosomal acidic phosphoproteins P1 and P2 are not required for cell viability but regulate the pattern of protein expression in Saccharomyces cerevisiae

6 September 2017

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The catalytic subunit of shiga-like toxin 1 interacts with ribosomal stalk proteins and is inhibited by their conserved C-terminal domain

14 September 2017

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Evidence for the importance of electrostatics in the function of two distinct families of ribosome inactivating toxins

26 June 2018

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Interaction between trichosanthin, a ribosome-inactivating protein, and the ribosomal stalk protein P2 by chemical shift perturbation and mutagenesis analyses

26 June 2018

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Control of phosphate release from elongation factor G by ribosomal protein L7/12.

26 June 2018

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Structural basis for the function of the ribosomal L7/12 stalk in factor binding and GTPase activation

26 June 2018

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Deletion of C-terminal residues of Escherichia coli ribosomal protein L10 causes the loss of binding of one L7/L12 dimer: ribosomes with one L7/L12 dimer are active

26 June 2018

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26 June 2018

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26 June 2018

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26 June 2018

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Pokeweed antiviral protein regulates the stability of its own mRNA by a mechanism that requires depurination but can be separated from depurination of the alpha-sarcin/ricin loop of rRNA.

26 June 2018

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Real-time kinetic analyses of the interaction of ricin toxin A-chain with ribosomes prove a conformational change involved in complex formation

3 September 2018

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Active center cleft residues of pokeweed antiviral protein mediate its high-affinity binding to the ribosomal protein L3.

3 September 2018

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3 September 2018

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The action of pokeweed antiviral protein and ricin A-chain on mutants in the alpha-sarcin loop of Escherichia coli 23S ribosomal RNA.

3 September 2018

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Effects of chemical modification of arginine residues outside the active site cleft of ricin A-chain on its RNA N-glycosidase activity for ribosomes

3 September 2018

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12 December 2020

Ricin A chain can be chemically cross-linked to the mammalian ribosomal proteins L9 and L10e

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12 December 2020

Interaction of elongation factor eEF-2 with ribosomal P proteins

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12 December 2020

Treatment of abrin and ricin with -mercaptoethanol opposite effects on their toxicity in mice and their ability to inhibit protein synthesis in a cell-free system

1 reference

12 December 2020

Ribosome inactivation by the toxic lectins abrin and ricin. Kinetics of the enzymic activity of the toxin A-chains

1 reference

12 December 2020

The Binding of Tritiated Elongation-Factors 1 and 2 to Ribosomes from Krebs II Mouse Ascites-Tumor Cells. The Influence of Various Antibiotics and Toxins

1 reference

12 December 2020

Protective Effect of Elongation Factor 2 on the Inactivation of Ribosomes by the Toxic Lectins Abrin and Ricin

1 reference

12 December 2020

Role of different regions of ribosomal proteins L7 and L10 in their complex formation and in the interaction with the ribosomal 50 S subunit

1 reference

12 December 2020

Involvement of arginine residues in inhibition of protein synthesis by ricin A-chain

1 reference

12 December 2020

Identifiers

DOI

10.1021/BI802371H

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19292477%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19292477%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

PubMed publication ID

19292477

1 reference