Pulmonary hypertension: therapeutic targets within the serotonin system. (Q37184405)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18536742%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

review article

3 references

26 October 2020

21 April 2021

Pulmonary hypertension: therapeutic targets within the serotonin system (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18536742%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

main subject

arterial hypertension

0 references

1 reference

21 April 2021

pulmonary hypertension

5 references

22 March 2019

25 June 2019

7 November 2019

1 June 2020

26 October 2020

1 reference

7 November 2019

1 reference

26 October 2020

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18536742%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

author name string

M R MacLean

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18536742%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

language of work or name

English

0 references

publication date

9 June 2008

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18536742%20AND%20SRC:MED&resulttype=core&format=json

British Journal of Pharmacology

8 January 2020

1 October 2008

2 references

26 October 2020

21 April 2021

6 references

22 March 2019

25 June 2019

7 November 2019

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18536742%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

26 October 2020

21 April 2021

155

1 reference

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8 January 2020

issue

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18536742%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

page(s)

455-462

1 reference

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Recent progress in the treatment of pulmonary arterial hypertension: expectation for rho-kinase inhibitors

8 January 2020

cites work

1 reference

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Serotonin transporter overexpression is responsible for pulmonary artery smooth muscle hyperplasia in primary pulmonary hypertension

6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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Attenuated hypoxic pulmonary hypertension in mice lacking the 5-hydroxytryptamine transporter gene.

6 September 2017

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26 June 2018

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26 June 2018

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3 September 2018

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3 September 2018

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3 September 2018

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3 September 2018

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3 September 2018

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3 September 2018

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3 September 2018

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3 September 2018

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3 September 2018

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3 September 2018

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Long-term treatment with a Rho-kinase inhibitor improves monocrotaline-induced fatal pulmonary hypertension in rats

3 September 2018

1 reference

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Serotonin receptor antagonist inhibits monocrotaline-induced pulmonary hypertension and prolongs survival in rats

3 September 2018

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Polymorphism of the Serotonin Transporter Gene and Pulmonary Hypertension in Chronic Obstructive Pulmonary Disease

3 September 2018

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3 September 2018

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Serotonin transporter inhibitors protect against hypoxic pulmonary hypertension

3 September 2018

1 reference

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Activation of GATA-4 by serotonin in pulmonary artery smooth muscle cells

3 September 2018

1 reference

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Dexfenfluramine protects against pulmonary hypertension in rats

3 September 2018

1 reference

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BMPR2 germline mutations in pulmonary hypertension associated with fenfluramine derivatives.

3 September 2018

1 reference

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5-HT1B receptor augmented 5-HT vasoconstrictor response of pulmonary artery in monocrotaline-induced pulmonary hypertensive rats

3 September 2018

1 reference

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Contribution of the 5-HT(1B) receptor to hypoxia-induced pulmonary hypertension: converging evidence using 5-HT(1B)-receptor knockout mice and the 5-HT(1B/1D)-receptor antagonist GR127935.

3 September 2018

1 reference

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H(2)O(2) signals 5-HT-induced ERK MAP kinase activation and mitogenesis of smooth muscle cells

3 September 2018

1 reference

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Heterozygous germline mutations in BMPR2, encoding a TGF-beta receptor, cause familial primary pulmonary hypertension

3 September 2018

1 reference

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3 September 2018

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Aminorex, fenfluramine, and chlorphentermine are serotonin transporter substrates. Implications for primary pulmonary hypertension

3 September 2018

1 reference

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Effects of chronic treatment with dexfenfluramine on serotonin in rat blood, brain and lung tissue

3 September 2018

1 reference

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The role of d-norfenfluramine in the indole-depleting effect of d-fenfluramine in the rat

3 September 2018

1 reference

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Increased plasma serotonin in primary pulmonary hypertension

3 September 2018

1 reference

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Effect of Tryptophan Hydroxylase 1 Deficiency on the Development of Hypoxia-Induced Pulmonary Hypertension

3 September 2018

1 reference

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Transgenic Mice Overexpressing the 5-Hydroxytryptamine Transporter Gene in Smooth Muscle Develop Pulmonary Hypertension

4 December 2018

1 reference

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Dysfunctional Smad Signaling Contributes to Abnormal Smooth Muscle Cell Proliferation in Familial Pulmonary Arterial Hypertension

4 December 2018

1 reference

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Dexfenfluramine does not worsen but moderates progression of chronic hypoxia-induced pulmonary hypertension

4 December 2018

1 reference

12 December 2020

Long-term inhibition of Rho kinase with fasudil attenuates high flow induced pulmonary artery remodeling in rats

1 reference

12 December 2020

Regression of chronic hypoxic pulmonary hypertension by simvastatin

1 reference

12 December 2020

Inhibition of serotonin-induced mitogenesis, migration, and ERK MAPK nuclear translocation in vascular smooth muscle cells by atorvastatin

1 reference

12 December 2020

Effects of combined therapy with a Rho-kinase inhibitor and prostacyclin on monocrotaline-induced pulmonary hypertension in rats

1 reference

12 December 2020

Serotonin transporter protein in pulmonary hypertensive rats treated with atorvastatin

1 reference

12 December 2020

Tryptophan hydroxylase 1 knockout and tryptophan hydroxylase 2 polymorphism: effects on hypoxic pulmonary hypertension in mice

1 reference

12 December 2020

p38 MAP kinase: essential role in hypoxia-mediated human pulmonary artery fibroblast proliferation

1 reference

12 December 2020

Mutations in the Gene Encoding Bone Morphogenetic Protein Receptor 2 in Patients With Idiopathic Pulmonary Arterial Hypertension

1 reference

12 December 2020

Regulation of serotonin-induced DNA synthesis of bovine pulmonary artery smooth muscle cells

1 reference

12 December 2020

Genetic anticipation and abnormal gender ratio at birth in familial primary pulmonary hypertension

1 reference

12 December 2020

Anorexic agents aminorex, fenfluramine, and dexfenfluramine inhibit potassium current in rat pulmonary vascular smooth muscle and cause pulmonary vasoconstriction

1 reference

12 December 2020

Treatment with 5-HT potentiates development of pulmonary hypertension in chronically hypoxic rats

1 reference

12 December 2020

Superoxide as an intermediate signal for serotonin-induced mitogenesis

1 reference

12 December 2020

Inhibition of serotonin-induced vascular smooth muscle cell proliferation by sarpogrelate

1 reference

12 December 2020

Dexfenfluramine increases pulmonary artery smooth muscle intracellular Ca2+, independent of membrane potential

1 reference

12 December 2020

Dexfenfluramine-induced contraction of human and rat isolated pulmonary arteries

1 reference

12 December 2020

Chronic hypoxia induces constitutive p38 mitogen-activated protein kinase activity that correlates with enhanced cellular proliferation in fibroblasts from rat pulmonary but not systemic arteries

1 reference

12 December 2020

Mutaciones en el gen que codifica BMPR2 en pacientes con hipertensión arterial pulmonar esporádica

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FBJP.2008.241

7 January 2021

inferred from DOI database lookup

Identifiers

DOI

10.1038/BJP.2008.241

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18536742%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18536742%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

PubMed publication ID

18536742

1 reference