Regulation of repertoire development through genetic control of DH reading frame preference (Q37186575)

18 August 2017

Regulation of repertoire development through genetic control of DH reading frame preference (English)

1 reference

18 August 2017

Gregory C Ippolito

3

0 references

Michael Zemlin

object named as

Michael Zemlin

1

0 references

Klaus Rajewsky

object named as

Klaus Rajewsky

9

0 references

author name string

Robert L Schelonka

2

1 reference

18 August 2017

Cosima Zemlin

4

1 reference

18 August 2017

Yingxin Zhuang

5

1 reference

18 August 2017

G Larry Gartland

6

1 reference

18 August 2017

Lars Nitschke

7

1 reference

18 August 2017

Jukka Pelkonen

8

1 reference

18 August 2017

Harry W Schroeder

10

1 reference

18 August 2017

language of work or name

English

0 references

publication date

1 December 2008

1 reference

18 August 2017

Journal of Immunology

1 reference

18 August 2017

181

1 reference

18 August 2017

12

1 reference

18 August 2017

8416-8424

1 reference

Preferential use of DH reading frame 2 alters B cell development and antigen-specific antibody production

18 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2680007

A hypothesis accounting for the paradoxical expression of the D gene segment in the BCR and the TCR.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2680007

Heterosubtypic immunity to influenza A virus infection requires a properly diversified antibody repertoire

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2680007

Forced usage of positively charged amino acids in immunoglobulin CDR-H3 impairs B cell development and antibody production

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2680007

B cell development pathways

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2680007

Anatomy of the antibody molecule

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2680007

Influence of coding-end sequence on coding-end processing in V(D)J recombination.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2680007

Organization, structure, and assembly of immunoglobulin heavy chain diversity DNA segments

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2680007

Three-dimensional structure of membrane and surface proteins

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2680007

Somatic generation of antibody diversity

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2680007

Joining of immunoglobulin heavy chain gene segments: implications from a chromosome with evidence of three D-JH fusions

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2680007

Sequence homologies, N sequence insertion and JH gene utilization in VHDJH joining: implications for the joining mechanism and the ontogenetic timing of Ly1 B cell and B-CLL progenitor generation

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2680007

Lack of N regions in fetal and neonatal mouse immunoglobulin V-D-J junctional sequences

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2680007

Recombination signal sequences restrict chromosomal V(D)J recombination beyond the 12/23 rule.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2680007

Predominance of VH-D-JH junctions occurring at sites of short sequence homology results in limited junctional diversity in neonatal antibodies.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2680007

Regulation of the antibody repertoire through control of HCDR3 diversity.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2680007

Extent to which homology can constrain coding exon junctional diversity in V(D)J recombination

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2680007

Coding end sequence can markedly affect the initiation of V(D)J recombination

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2680007

Structure and evolution of mammalian VH families

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2680007

B cell development regulated by gene rearrangement: arrest of maturation by membrane-bound D mu protein and selection of DH element reading frames

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2680007

The basis for the mechanistic bias for deletional over inversional V(D)J recombination

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2680007

Categorical selection of the antibody repertoire in splenic B cells.

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2680007

A single DH gene segment creates its own unique CDR-H3 repertoire and is sufficient for B cell development and immune function

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2680007

Development of the expressed Ig CDR-H3 repertoire is marked by focusing of constraints in length, amino acid use, and charge that are first established in early B cell progenitors

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2680007

Diversity in the CDR3 region of V(H) is sufficient for most antibody specificities

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2680007

IgM heavy chain complementarity-determining region 3 diversity is constrained by genetic and somatic mechanisms until two months after birth.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2680007

Deletion of the DQ52 element within the Ig heavy chain locus leads to a selective reduction in VDJ recombination and altered D gene usage

3 September 2018

1 reference

12 December 2020

Novel immunoglobulin heavy chains are produced from DJH gene segment rearrangements in lymphoid cells

1 reference

12 December 2020

Specific H chain junctional diversity may be required for non-T15 antibodies to bind phosphorylcholine

1 reference

12 December 2020

Only DFL16, DSP2, and DQ52 gene families exist in mouse immunoglobulin heavy chain diversity gene loci, of which DFL16 and DSP2 originate from the same primordial DH gene

1 reference

12 December 2020

Surrogate Light Chain Expression Is Required to Establish Immunoglobulin Heavy Chain Allelic Exclusion during Early B Cell Development

1 reference

12 December 2020

10.4049/JIMMUNOL.181.12.8416

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30 July 2022

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30 July 2022

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30 July 2022

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30 July 2022