Regulation of the brain isoprenoids farnesyl- and geranylgeranylpyrophosphate is altered in male Alzheimer patients. (Q37187284)

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28 January 2020

title

Regulation of the brain isoprenoids farnesyl- and geranylgeranylpyrophosphate is altered in male Alzheimer patients (English)

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28 January 2020

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0 references

5

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28 January 2020

author name string

Gunter P Eckert

1

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28 January 2020

Gero P Hooff

2

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28 January 2020

Dana M Strandjord

3

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28 January 2020

Urule Igbavboa

4

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28 January 2020

Walter E Müller

6

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28 January 2020

W Gibson Wood

7

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28 January 2020

publication date

21 May 2009

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28 January 2020

published in

Neurobiology of Disease

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28 January 2020

volume

35

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28 January 2020

issue

2

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28 January 2020

page(s)

251-257

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Isoprenoid quantitation in human brain tissue: a validated HPLC-fluorescence detection method for endogenous farnesyl- (FPP) and geranylgeranylpyrophosphate (GGPP).

28 January 2020

cites work

1 reference

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Statin therapy is associated with reduced neuropathologic changes of Alzheimer disease

6 September 2017

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6 September 2017

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Isoprenoids and Alzheimer's disease: a complex relationship

6 September 2017

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6 September 2017

Isoprenylated proteins

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Regulation of fatty acid synthesis by farnesyl pyrophosphate

6 September 2017

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Diverse compounds mimic Alzheimer disease-causing mutations by augmenting Abeta42 production

6 September 2017

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Protein prenylation: a pivotal posttranslational process

6 September 2017

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Proteolysis and sterol regulation

6 September 2017

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Rho proteins: linking signaling with membrane trafficking

6 September 2017

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Small GTP-binding proteins

6 September 2017

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Presenilins interact with Rab11, a small GTPase involved in the regulation of vesicular transport

6 September 2017

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Statins reduce amyloid-beta production through inhibition of protein isoprenylation

6 September 2017

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Statins cause intracellular accumulation of amyloid precursor protein, beta-secretase-cleaved fragments, and amyloid beta-peptide via an isoprenoid-dependent mechanism.

14 September 2017

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Association of active gamma-secretase complex with lipid rafts.

14 September 2017

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Chronic administration of statins alters multiple gene expression patterns in mouse cerebral cortex

14 September 2017

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Quantitative determination of farnesyl and geranylgeranyl diphosphate levels in mammalian tissue

14 September 2017

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Simultaneous determination of farnesyl and geranylgeranyl pyrophosphate levels in cultured cells

26 June 2018

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Implication of the small GTPase Rac1 in the generation of reactive oxygen species in response to beta-amyloid in C6 astroglioma cells

26 June 2018

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Reduced risk of incident AD with elective statin use in a clinical trial cohort

26 June 2018

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Neuroanatomical correlates of neuropsychiatric symptoms in Alzheimer's disease.

3 September 2018

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3 September 2018

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Rab6 is increased in Alzheimer's disease brain and correlates with endoplasmic reticulum stress.

3 September 2018

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3 September 2018

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Rab6 membrane association is dependent of Presenilin 1 and cellular phosphorylation events

3 September 2018

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Feedback inhibition of polyisoprenyl pyrophosphate synthesis from mevalonate in vitro. Implications for protein prenylation

3 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19464372

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.NBD.2009.05.005

1 reference

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28 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19464372%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

1 reference