PTPN2, a candidate gene for type 1 diabetes, modulates interferon-gamma-induced pancreatic beta-cell apoptosis (Q37193767)

18 August 2017

PTPN2, a candidate gene for type 1 diabetes, modulates interferon-gamma-induced pancreatic beta-cell apoptosis (English)

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18 August 2017

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Alessandra K. Cardozo

object named as

Alessandra K Cardozo

5

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Miriam Cnop

object named as

Miriam Cnop

3

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Piero Marchetti

object named as

Piero Marchetti

8

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author name string

Fabrice Moore

1

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18 August 2017

Maikel L Colli

2

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18 August 2017

Mariana Igoillo Esteve

4

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18 August 2017

Daniel A Cunha

6

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18 August 2017

Marco Bugliani

7

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18 August 2017

Décio L Eizirik

9

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18 August 2017

language of work or name

English

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publication date

31 March 2009

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18 August 2017

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18 August 2017

58

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18 August 2017

1283-1291

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18 August 2017

6

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Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported

18 August 2017

start time

27 August 2021

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April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

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Newly identified loci highlight beta cell dysfunction as a key cause of type 2 diabetes: where are the insulin resistance genes?

6 September 2017

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Use of a systems biology approach to understand pancreatic beta-cell death in Type 1 diabetes

6 September 2017

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6 September 2017

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The CVB and etiology of type 1 diabetes

6 September 2017

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PTP1B and TC-PTP: regulators of transformation and tumorigenesis

6 September 2017

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STAT3 as a target for inducing apoptosis in solid and hematological tumors

6 September 2017

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6 September 2017

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6 September 2017

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Robust associations of four new chromosome regions from genome-wide analyses of type 1 diabetes

6 September 2017

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T-cell protein tyrosine phosphatase, distinctively expressed in activated-B-cell-like diffuse large B-cell lymphomas, is the nuclear phosphatase of STAT6

6 September 2017

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T1DBase: integration and presentation of complex data for type 1 diabetes research

6 September 2017

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Selective inhibition of eukaryotic translation initiation factor 2 alpha dephosphorylation potentiates fatty acid-induced endoplasmic reticulum stress and causes pancreatic beta-cell dysfunction and apoptosis

6 September 2017

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PTP1B and TC-PTP: novel roles in immune-cell signaling

6 September 2017

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T-cell protein tyrosine phosphatase (Tcptp) is a negative regulator of colony-stimulating factor 1 signaling and macrophage differentiation

6 September 2017

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Role of PTPN22 in type 1 diabetes and other autoimmune diseases

6 September 2017

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Regulation of gene-activation pathways by PIAS proteins in the immune system

6 September 2017

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Toll-like receptor 3 and STAT-1 contribute to double-stranded RNA+ interferon-gamma-induced apoptosis in primary pancreatic beta-cells

6 September 2017

1 reference

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Cytoplasmic protein tyrosine phosphatases, regulation and function: the roles of PTP1B and TC-PTP.

6 September 2017

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Genome-wide association studies: theoretical and practical concerns

6 September 2017

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T-cell protein tyrosine phosphatase deletion results in progressive systemic inflammatory disease

6 September 2017

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Regulation of insulin receptor signaling by the protein tyrosine phosphatase TCPTP

6 September 2017

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A nuclear protein tyrosine phosphatase activates p53 and induces caspase-1-dependent apoptosis

6 September 2017

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Identification of a nuclear Stat1 protein tyrosine phosphatase

6 September 2017

1 reference

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A choice of death--the signal-transduction of immune-mediated beta-cell apoptosis

6 September 2017

1 reference

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A comprehensive analysis of cytokine-induced and nuclear factor-kappa B-dependent genes in primary rat pancreatic beta-cells

6 September 2017

1 reference

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Structural and evolutionary relationships among protein tyrosine phosphatase domains

6 September 2017

1 reference

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Epidermal growth factor receptor and the adaptor protein p52Shc are specific substrates of T-cell protein tyrosine phosphatase

6 September 2017

1 reference

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Glucose promotes survival of rat pancreatic beta cells by activating synthesis of proteins which suppress a constitutive apoptotic program

6 September 2017

1 reference

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Analysis of nitrate, nitrite, and [15N]nitrate in biological fluids

6 September 2017

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cDNA isolated from a human T-cell library encodes a member of the protein-tyrosine-phosphatase family

6 September 2017

1 reference

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Cloning and characterization of a mouse cDNA encoding a cytoplasmic protein-tyrosine-phosphatase

6 September 2017

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Establishment of 2-mercaptoethanol-dependent differentiated insulin-secreting cell lines

6 September 2017

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Toll-like receptor 4 suppression leads to islet allograft survival

6 September 2017

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Discovery of Gene Networks Regulating Cytokine-Induced Dysfunction and Apoptosis in Insulin-Producing INS-1 Cells

14 September 2017

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Insulin receptor signaling in the beta-cell influences insulin gene expression and insulin content: evidence for autocrine beta-cell regulation

14 September 2017

1 reference

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Replication of signals from recent studies of Crohn's disease identifies previously unknown disease loci for ulcerative colitis

28 September 2017

1 reference

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Disruption of the gamma-interferon signaling pathway at the level of signal transducer and activator of transcription-1 prevents immune destruction of beta-cells

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2682688

The transcription factor Stat3 is dispensable for pancreatic beta-cell development and function.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2682688

Diabetogenic potential of human pathogens uncovered in experimentally permissive beta-cells.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2682688

IL-1beta and IFN-gamma induce the expression of diverse chemokines and IL-15 in human and rat pancreatic islet cells, and in islets from pre-diabetic NOD mice.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2682688

Prolonged exposure to free fatty acids has cytostatic and pro-apoptotic effects on human pancreatic islets: evidence that beta-cell death is caspase mediated, partially dependent on ceramide pathway, and Bcl-2 regulated.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2682688

Monocyte chemoattractant protein-1 is expressed in pancreatic islets from prediabetic NOD mice and in interleukin-1 beta-exposed human and rat islet cells

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2682688

Double-stranded RNA cooperates with interferon-gamma and IL-1 beta to induce both chemokine expression and nuclear factor-kappa B-dependent apoptosis in pancreatic beta-cells: potential mechanisms for viral-induced insulitis and beta-cell death in ty

3 September 2018

1 reference

12 December 2020

Global profiling of double stranded RNA- and IFN-?-induced genes in rat pancreatic beta cells

1 reference

12 December 2020

A new in vitro model for the study of pancreatic A and B cells

1 reference

12 December 2020

Effect of nutrients, hormones and serum on survival of rat islet beta cells in culture

1 reference

12 December 2020

Quantification of murine cytokine mRNAs using real time quantitative reverse transcriptase PCR

1 reference

12 December 2020

Identification of tyrosine phosphatases that dephosphorylate the insulin receptor. A brute force approach based on "substrate-trapping" mutants

1 reference

12 December 2020

Global profiling of coxsackievirus- and cytokine-induced gene expression in human pancreatic islets

1 reference

12 December 2020

Cytokine-induced proapoptotic gene expression in insulin-producing cells is related to rapid, sustained, and nonoscillatory nuclear factor-kappaB activation

1 reference

12 December 2020

TC-PTP-deficient bone marrow stromal cells fail to support normal B lymphopoiesis due to abnormal secretion of interferon-{gamma}

1 reference

12 December 2020

Deletion of STAT-1 pancreatic islets protects against streptozotocin-induced diabetes and early graft failure but not against late rejection

1 reference

12 December 2020

Islet beta-cell death - fuel to sustain autoimmunity?

1 reference

12 December 2020

Essential Role for Signal Transducer and Activator of Transcription-1 in Pancreatic -Cell Death and Autoimmune Type 1 Diabetes of Nonobese Diabetic Mice

1 reference

12 December 2020

Identification of novel cytokine-induced genes in pancreatic beta-cells by high-density oligonucleotide arrays

1 reference

12 December 2020

Identifiers

DOI

10.2337/DB08-1510

1 reference

18 August 2017

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18 August 2017

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