MYB function in normal and cancer cells (Q37198576)

18 August 2017

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title

MYB function in normal and cancer cells (English)

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18 August 2017

Robert G Ramsay

1

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18 August 2017

Thomas J Gonda

series ordinal

2

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18 August 2017

language of work or name

English

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publication date

1 July 2008

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18 August 2017

Nature Reviews Cancer

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18 August 2017

8

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18 August 2017

7

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18 August 2017

523-534

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https://scigraph.springernature.com/pub.10.1038/nrc2439

18 August 2017

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cites work

Structure of the protein encoded by the chicken proto-oncogene c-myb

1 reference

Two modes of c-myb activation in virus-induced mouse myeloid tumors

21 January 2018

1 reference

C/EBP, c-Myb, and PU.1 cooperate to regulate the neutrophil elastase promoter

21 January 2018

1 reference

Interaction of C/EBPbeta and v-Myb is required for synergistic activation of the mim-1 gene

21 January 2018

1 reference

Myb and Ets proteins cooperate to transactivate an early myeloid gene

21 January 2018

1 reference

Distinct cellular factors regulate the c-myb promoter through its E2F element

21 January 2018

1 reference

Expression of a proto-oncogene (proto-myb) in hemopoietic tissues of mice

21 January 2018

1 reference

Constitutive expression of a c-myb cDNA blocks Friend murine erythroleukemia cell differentiation

21 January 2018

1 reference

Positive autoregulation of c-myb expression via Myb binding sites in the 5' flanking region of the human c-myb gene

21 January 2018

1 reference

c-Myb and Bcl-x overexpression predicts poor prognosis in colorectal cancer: clinical and experimental findings

21 January 2018

1 reference

Role of secondary structure in discrimination between constitutive and inducible activators

21 January 2018

1 reference

Protein truncation is required for the activation of the c-myb proto-oncogene

21 January 2018

1 reference

A putative second cell-derived oncogene of the avian leukaemia retrovirus E26.

21 January 2018

1 reference

Chicken hematopoietic cells transformed by seven strains of defective avian leukemia viruses display three distinct phenotypes of differentiation

31 March 2020

1 reference

Structural organization and nucleotide sequence of mouse c-myb oncogene: activation in ABPL tumors is due to viral integration in an intron which results in the deletion of the 5' coding sequences

31 March 2020

1 reference

Truncation of the c-myb gene by a retroviral integration in an interleukin 3-dependent myeloid leukemia cell line

31 March 2020

1 reference

Aberrant expression of an amplified c-myb oncogene in two cell lines from a colon carcinoma.

31 March 2020

1 reference

Suppressor screen in Mpl-/- mice: c-Myb mutation causes supraphysiological production of platelets in the absence of thrombopoietin signaling

31 March 2020

1 reference

Progression through key stages of haemopoiesis is dependent on distinct threshold levels of c-Myb.

31 March 2020

1 reference

c-Myb is required for progenitor cell homeostasis in colonic crypts.

31 March 2020

1 reference

c-Myb Is Required for Neural Progenitor Cell Proliferation and Maintenance of the Neural Stem Cell Niche in Adult Brain

31 March 2020

1 reference

c-Myb a stem-progenitor cell regulator in multiple tissue compartments.

31 March 2020

1 reference

c-Myb and p300 regulate hematopoietic stem cell proliferation and differentiation

31 March 2020

1 reference

Mutations in the MYB intron I regulatory sequence increase transcription in colon cancers

31 March 2020

1 reference

Microsatellite deletions in the c-myb transcriptional attenuator region associated with over-expression in colon tumour cell lines

31 March 2020

1 reference

Mechanism of and requirement for estrogen-regulated MYB expression in estrogen-receptor-positive breast cancer cells

31 March 2020

1 reference

The C-MYB locus is involved in chromosomal translocation and genomic duplications in human T-cell acute leukemia (T-ALL), the translocation defining a new T-ALL subtype in very young children.

31 March 2020

1 reference

Truncated c-Myb expression in the human leukemia cell line TK-6.

31 March 2020

1 reference

Isolation of human cDNA clones of myb-related genes, A-myb and B-myb

31 March 2020

1 reference

Functional evolution of the Myb oncogene family

31 March 2020

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Mouse A-myb encodes a trans-activator and is expressed in mitotically active cells of the developing central nervous system, adult testis and B lymphocytes

31 March 2020

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The T cell-dependent B cell immune response and germinal center reaction are intact in A-myb-deficient mice

31 March 2020

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Arrest of spermatogenesis and defective breast development in mice lacking A-myb

31 March 2020

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B-myb is required for inner cell mass formation at an early stage of development

31 March 2020

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A B-myb promoter corepressor site facilitates in vivo occupation of the adjacent E2F site by p107 x E2F and p130 x E2F complexes

31 March 2020

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E2F4-RB and E2F4-p107 complexes suppress gene expression by transforming growth factor beta through E2F binding sites

31 March 2020

1 reference

[Interaction of E2F/Rb family members with factor binding to co-repressor element on B-myb and E2F1 promoters]

31 March 2020

1 reference

Interaction of E2F-Rb family members with corepressors binding to the adjacent E2F site

31 March 2020

1 reference

Tissue-wide expression profiling using cDNA subtraction and microarrays to identify tumor-specific genes

31 March 2020

1 reference

Viral myb oncogene encodes a sequence-specific DNA-binding activity.

31 March 2020

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CBP as a transcriptional coactivator of c-Myb

31 March 2020

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Interaction of the co-activator CBP with Myb proteins: effects on Myb-specific transactivation and on the cooperativity with NF-M

31 March 2020

1 reference

v-Myb represses the transcription of Ets-2.

31 March 2020

1 reference

GATA-1 and c-myb crosstalk during red blood cell differentiation through GATA-1 binding sites in the c-myb promoter.

31 March 2020

1 reference

Inhibitory interaction of c-Myb and GATA-1 via transcriptional co-activator CBP

31 March 2020

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Tumorigenic N-terminal deletions of c-Myb modulate DNA binding, transactivation, and cooperativity with C/EBP

31 March 2020

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Oncogenic activation of c-Myb by carboxyl-terminal truncation leads to decreased proteolysis by the ubiquitin-26S proteasome pathway

31 March 2020

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Hyperphosphorylation and increased proteolytic breakdown of c-Myb induced by the inhibition of Ser/Thr protein phosphatases

31 March 2020

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Constitutive c-Myb amino-terminal phosphorylation and DNA binding activity uncoupled during entry and passage through the cell cycle

31 March 2020

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Myb DNA binding inhibited by phosphorylation at a site deleted during oncogenic activation

31 March 2020

1 reference

Differential regulation of c-Myb-induced transcription activation by a phosphorylation site in the negative regulatory domain

31 March 2020

1 reference

p38MAPK delta controls c-Myb degradation in response to stress

31 March 2020

1 reference

An inhibitor of Bcl-2 family proteins induces regression of solid tumours

31 March 2020

1 reference

Increased affinity of c-Myb for CREB-binding protein (CBP) after CBP-induced acetylation

31 March 2020

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c-Myb acetylation at the carboxyl-terminal conserved domain by transcriptional co-activator p300.

31 March 2020

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Covalent attachment of the SUMO-1 protein to the negative regulatory domain of the c-Myb transcription factor modifies its stability and transactivation capacity

31 March 2020

1 reference

Stress-induced inactivation of the c-Myb transcription factor through conjugation of SUMO-2/3 proteins

31 March 2020

1 reference

Myb: an old oncoprotein with new roles

31 March 2020

1 reference

c-Myb transcription is activated by protein kinase B (PKB) following interleukin 2 stimulation of Tcells and is required for PKB-mediated protection from apoptosis

31 March 2020

1 reference

Myb proteins in life, death and differentiation

31 March 2020

1 reference

Differential expression of c-myb mRNA in murine B lymphomas by a block to transcription elongation

31 March 2020

1 reference

Expression of myb, myc and fos proto-oncogenes during the differentiation of a murine myeloid leukaemia

31 March 2020

1 reference

Changes in gene expression associated with induced differentiation of erythroleukemia: protooncogenes, globin genes, and cell division

31 March 2020

1 reference

Colon epithelial cell differentiation is inhibited by constitutive c-myb expression or mutant APC plus activated RAS.

31 March 2020

1 reference

The beta-catenin/TCF-4 complex imposes a crypt progenitor phenotype on colorectal cancer cells

31 March 2020

1 reference

A class of hybrid polar inducers of transformed cell differentiation inhibits histone deacetylases.

31 March 2020

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Induction of transformed cells to terminal differentiation

31 March 2020

1 reference

c-myb intron I protein binding and association with transcriptional activity in leukemic cells

31 March 2020

1 reference

The interferon regulatory factors 1 and 2 bind to a segment of the human c-myb first intron: possible role in the regulation of c-myb expression.

31 March 2020

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Transcriptional elongation of c-myb is regulated by NF-kappaB (p50/RelB).

31 March 2020

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Members of the nuclear factor kappa B family transactivate the murine c-myb gene

31 March 2020

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31 March 2020

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Positive and negative determinants of target gene specificity in myb transcription factors.

31 March 2020

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Oncogenic mutations cause dramatic, qualitative changes in the transcriptional activity of c-Myb

31 March 2020

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Differential expression of the amv gene in human hematopoietic cells

31 March 2020

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A functional c-myb gene is required for normal murine fetal hepatic hematopoiesis

31 March 2020

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c-Myb is essential for early T cell development

31 March 2020

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Critical functions for c-Myb at three checkpoints during thymocyte development

31 March 2020

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c-Myb is critical for B cell development and maintenance of follicular B cells

31 March 2020

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Defective stem cell factor expression in c-myb null fetal liver stroma

31 March 2020

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Initiation of adult myelopoiesis can occur in the absence of c-Myb whereas subsequent development is strictly dependent on the transcription factor

31 March 2020

1 reference

Delineation of three functional domains of the transcriptional activator encoded by the c-myb protooncogene

31 March 2020

1 reference

Stem cells in gastrointestinal epithelium: numbers, characteristics and death

31 March 2020

1 reference

Differentiation and self-renewal in the mouse gastrointestinal epithelium

31 March 2020

1 reference

Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation

31 March 2020

1 reference

Neurogenesis in the adult brain

31 March 2020

1 reference

Genetics of human hydrocephalus.

31 March 2020

1 reference

The neurodevelopmental price of survival in children with malignant brain tumours

31 March 2020

1 reference

Neurophysiological findings in long-term survivors of acute lymphoblastic leukaemia in childhood treated with the BFM protocol 81 SR-A/B.

31 March 2020

1 reference

White matter anisotropy in post-treatment childhood cancer survivors: preliminary evidence of association with neurocognitive function.

31 March 2020

1 reference

A role for adult neurogenesis in spatial long-term memory.

31 March 2020

1 reference

Cognitive sequelae of brain tumor treatment

31 March 2020

1 reference

Increased c-myb mRNA expression in Barrett's esophagus and Barrett's-associated adenocarcinoma

31 March 2020

1 reference

Coding sequence and intron-exon junctions of the c-myb gene are intact in the chronic phase and blast crisis stages of chronic myeloid leukemia patients.

31 March 2020

1 reference

Mutation screening of the c-MYB negative regulatory domain in acute and chronic myeloid leukaemia

31 March 2020

1 reference

An oligomer complementary to c-myb-encoded mRNA inhibits proliferation of human myeloid leukemia cell lines

31 March 2020

1 reference

Normal and leukemic hematopoietic cells manifest differential sensitivity to inhibitory effects of c-myb antisense oligodeoxynucleotides: an in vitro study relevant to bone marrow purging

31 March 2020

1 reference

c-Myb is an essential downstream target for homeobox-mediated transformation of hematopoietic cells.

31 March 2020

1 reference

Requirement of c-Myb for p210(BCR/ABL)-dependent transformation of hematopoietic progenitors and leukemogenesis

31 March 2020

1 reference

Duplication of the MYB oncogene in T cell acute lymphoblastic leukemia

31 March 2020

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Alu elements mediate MYB gene tandem duplication in human T-ALL

31 March 2020

1 reference

Biological characterization and oncogene expression in human colorectal carcinoma cell lines

31 March 2020

1 reference

Oncogene alterations in rat colon tumors induced by N-methyl-N-nitrosourea

31 March 2020

1 reference

Mapping of amplified c-myb oncogene, sister chromatid exchanges, and karyotypic analysis of the COLO 205 colon carcinoma cell line

31 March 2020

1 reference

Targeting c-Myb expression in human disease

31 March 2020

1 reference

A gene-expression signature as a predictor of survival in breast cancer

31 March 2020

1 reference

Profiling of estrogen up- and down-regulated gene expression in human breast cancer cells: insights into gene networks and pathways underlying estrogenic control of proliferation and cell phenotype

31 March 2020

1 reference

Oligodeoxynucleotide-based therapeutics for human leukemias

31 March 2020

1 reference

Disruption of Rb/E2F pathway results in increased cyclooxygenase-2 expression and activity in prostate epithelial cells

31 March 2020

1 reference

Effect on tumor cells of blocking survival response to glucose deprivation

31 March 2020

1 reference

GRP78 induction in cancer: therapeutic and prognostic implications.

31 March 2020

1 reference

Mechanistic studies of a peptidic GRP78 ligand for cancer cell-specific drug delivery

31 March 2020

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Characterization of the c-Myb-responsive region and regulation of the human type I collagen alpha 2 chain gene by c-Myb.

31 March 2020

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Collagen loss and impaired wound healing is associated with c-Myb deficiency.

31 March 2020

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Distinct changes in gene expression induced by A-Myb, B-Myb and c-Myb proteins

31 March 2020

1 reference

MicroRNAs modulate hematopoietic lineage differentiation

31 March 2020

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Oncomirs - microRNAs with a role in cancer

31 March 2020

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MiR-150 controls B cell differentiation by targeting the transcription factor c-Myb

31 March 2020

1 reference

31 March 2020

Transformation by v-Myb

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Activation of c-myb by carboxy-terminal truncation: relationship to transformation of murine haemopoietic cells in vitro.

31 March 2020

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Transactivation and transformation by Myb are negatively regulated by a leucine-zipper structure

31 March 2020

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Alternative RNA splicing produces multiple forms of c-Myb with unique transcriptional activities

31 March 2020

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Molecular mechanisms associated with the regulation of apoptosis by the two alternatively spliced products of c-Myb

31 March 2020

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c-Myb function in fibroblasts

31 March 2020

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Expression of the c-myb proto-oncogene during cellular proliferation

31 March 2020

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Factors regulating the transcriptional elongation activity of RNA polymerase II

31 March 2020

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A chromatin landmark and transcription initiation at most promoters in human cells

31 March 2020

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Breaking barriers to transcription elongation

31 March 2020

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Neoplastic transformation by E26 leukemia virus is mediated by a single protein containing domains of gag and myb genes

31 March 2020

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inferred from DOI database lookup

7 January 2021

based on heuristic

1 reference

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/NRC2439

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Dimensions Publication ID

18 August 2017

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1 reference