Antirheumatic drug response signatures in human chondrocytes: potential molecular targets to stimulate cartilage regeneration (Q37207085)

18 August 2017

Antirheumatic drug response signatures in human chondrocytes: potential molecular targets to stimulate cartilage regeneration (English)

1 reference

18 August 2017

1 reference

ChEBI release 2020-05-28

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Kristin Andreas

1

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18 August 2017

Thomas Häupl

2

1 reference

18 August 2017

Carsten Lübke

3

1 reference

18 August 2017

Jochen Ringe

4

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18 August 2017

Lars Morawietz

5

1 reference

18 August 2017

Anja Wachtel

6

1 reference

18 August 2017

Michael Sittinger

7

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18 August 2017

Christian Kaps

8

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18 August 2017

3 February 2009

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Arthritis Research and Therapy

18 August 2017

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18 August 2017

11

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18 August 2017

1

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18 August 2017

R15

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https://scigraph.springernature.com/pub.10.1186/ar2605

18 August 2017

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Clinical pharmacology and pharmacogenetics of thiopurines

6 September 2017

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Key regulatory molecules of cartilage destruction in rheumatoid arthritis: an in vitro study

6 September 2017

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The burden of rheumatoid arthritis and access to treatment: a medical overview

6 September 2017

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6 September 2017

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Gene expression profiling of rheumatoid arthritis synovial cells treated with antirheumatic drugs

6 September 2017

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Chemokine inhibition in inflammatory arthritis

6 September 2017

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New cytokine targets in inflammatory rheumatic diseases

6 September 2017

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Contemporary concepts of inflammation, damage and repair in rheumatic diseases.

6 September 2017

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Mechanisms of disease: the molecular and cellular basis of joint destruction in rheumatoid arthritis

6 September 2017

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Molecular and cellular basis of rheumatoid joint destruction

6 September 2017

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Synovial fibroblasts: key players in rheumatoid arthritis

6 September 2017

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Matrix metalloproteinases: role in arthritis

6 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2688247

Rheumatoid arthritis: an overview of new and emerging therapies

6 September 2017

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DNA microarray allows molecular profiling of rheumatoid arthritis and identification of pathophysiological targets.

6 September 2017

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The regulation of chondrocyte function by proinflammatory mediators: prostaglandins and nitric oxide.

6 September 2017

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Perspectives and limitations of gene expression profiling in rheumatology: new molecular strategies

6 September 2017

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Methotrexate as the "anchor drug" for the treatment of early rheumatoid arthritis.

6 September 2017

1 reference

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Glucocorticoids in the treatment of early and late RA

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2688247

Rheumatoid arthritis in 2003: where are we now with treatment?

6 September 2017

1 reference

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High CXCR3 expression in synovial mast cells associated with CXCL9 and CXCL10 expression in inflammatory synovial tissues of patients with rheumatoid arthritis

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2688247

Pathogenesis of bone and cartilage destruction in rheumatoid arthritis

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2688247

Therapeutic strategies for rheumatoid arthritis

6 September 2017

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Summaries of Affymetrix GeneChip probe level data

6 September 2017

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Genesis: cluster analysis of microarray data

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2688247

Metabolic activation stimulates acid production in synovial fibroblasts

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2688247

A review of controlled clinical trials examining the effects of antimalarial compounds and gold compounds on radiographic progression in rheumatoid arthritis

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2688247

KEGG: kyoto encyclopedia of genes and genomes

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2688247

Glucocorticosteroids in the management of rheumatoid arthritis

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2688247

Cyr61, product of a growth factor-inducible immediate-early gene, regulates chondrogenesis in mouse limb bud mesenchymal cells

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2688247

The modular architecture of a new family of growth regulators related to connective tissue growth factor

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2688247

Impact of NSAID and steroids on cartilage destruction in murine antigen induced arthritis

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2688247

The anti-rheumatic gold salt aurothiomalate suppresses interleukin-1beta-induced hyaluronan accumulation by blocking HAS1 transcription and by acting as a COX-2 transcriptional repressor

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2688247

Prostaglandin E2 induces IL-23 production in bone marrow-derived dendritic cells

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2688247

Serum response elements activate and cAMP responsive elements inhibit expression of transcription factor Egr-1 in synovial fibroblasts of rheumatoid arthritis patients

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2688247

Characterization of SV40T antigen immortalized human synovial fibroblasts: maintained expression patterns of EGR-1, HLA-DR and some surface receptors

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2688247

CCN family 2/connective tissue growth factor modulates BMP signalling as a signal conductor, which action regulates the proliferation and differentiation of chondrocytes

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2688247

Modulation of cell recruitment by anti-inflammatory agents in antigen-induced arthritis

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2688247

Interleukin-17 promotes autoimmunity by triggering a positive-feedback loop via interleukin-6 induction.

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2688247

Aurothiomalate inhibits COX-2 expression in chondrocytes and in human cartilage possibly through its effects on COX-2 mRNA stability

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2688247

Connective tissue growth factor is a biomarker and mediator of kidney allograft fibrosis.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2688247

Gene expression profiling of human articular cartilage grafts generated by tissue engineering.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2688247

Serum levels of cartilage oligomeric matrix protein (COMP): a rapid decrease in patients with active rheumatoid arthritis undergoing intravenous steroid treatment

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2688247

Selective COX-2 inhibition prevents proinflammatory cytokine-induced cartilage damage

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2688247

Chondrocyte death induced by pathological concentration of chemokine stromal cell-derived factor-1

3 September 2018

1 reference

12 December 2020

Differential gene expression in synovium of rheumatoid arthritis and osteoarthritis

1 reference

12 December 2020

Stimulation of matrix metalloprotease 3 release from human chondrocytes by the interaction of stromal cell-derived factor 1 and CXC chemokine receptor 4

1 reference

12 December 2020

Sex steroid metabolism in the tibial growth plate of the rat

1 reference

12 December 2020

The Effect of Glucocorticoids on Joint Destruction in Rheumatoid Arthritis

1 reference

12 December 2020

Serum levels of connective tissue growth factor are elevated in patients with systemic sclerosis: association with extent of skin sclerosis and severity of pulmonary fibrosis

1 reference

12 December 2020

Identifiers

DOI

10.1186/AR2605

1 reference

Dimensions Publication ID

18 August 2017

0 references

1 reference

18 August 2017

1 reference